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Related papers: Optimizing OOD Detection in Molecular Graphs: A No…

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A well-known limitation of existing molecular generative models is that the generated molecules highly resemble those in the training set. To generate truly novel molecules that may have even better properties for de novo drug discovery,…

Biomolecules · Quantitative Biology 2023-06-06 Seul Lee , Jaehyeong Jo , Sung Ju Hwang

Out-of-distribution (OOD) detection plays a crucial role in ensuring the safety and reliability of deep neural networks in various applications. While there has been a growing focus on OOD detection in visual data, the field of textual OOD…

Computation and Language · Computer Science 2024-04-10 Li-Ming Zhan , Bo Liu , Xiao-Ming Wu

Deep Learning (DL) models tend to perform poorly when the data comes from a distribution different from the training one. In critical applications such as medical imaging, out-of-distribution (OOD) detection helps to identify such data…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Daria Frolova , Anton Vasiliuk , Mikhail Belyaev , Boris Shirokikh

Out-of-distribution (OOD) detection is critical for the safe deployment of machine learning systems in safety-sensitive domains. Diffusion models have recently emerged as powerful generative models, capable of capturing complex data…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Shirin Shoushtari , Yi Wang , Xiao Shi , M. Salman Asif , Ulugbek S. Kamilov

Out-of-distribution (OOD) detection is essential for model trustworthiness which aims to sensitively identify semantic OOD samples and robustly generalize for covariate-shifted OOD samples. However, we discover that the superior OOD…

Machine Learning · Computer Science 2024-10-16 Qingyang Zhang , Qiuxuan Feng , Joey Tianyi Zhou , Yatao Bian , Qinghua Hu , Changqing Zhang

In medical imaging, unsupervised out-of-distribution (OOD) detection offers an attractive approach for identifying pathological cases with extremely low incidence rates. In contrast to supervised methods, OOD-based approaches function…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Lemar Abdi , Francisco Caetano , Amaan Valiuddin , Christiaan Viviers , Hamdi Joudeh , Fons van der Sommen

Detecting deepfakes has become a critical challenge in Computer Vision and Artificial Intelligence. Despite significant progress in detection techniques, generalizing them to open-set scenarios continues to be a persistent difficulty.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-04 Luca Maiano , Fabrizio Casadei , Irene Amerini

Generative information retrieval methods retrieve documents by directly generating their identifiers. Much effort has been devoted to developing effective generative IR models. Less attention has been paid to the robustness of these models.…

Information Retrieval · Computer Science 2024-12-30 Yu-An Liu , Ruqing Zhang , Jiafeng Guo , Changjiang Zhou , Maarten de Rijke , Xueqi Cheng

Out-of-distribution (OOD) detection is critical to ensure the safe deployment of deep learning models in critical applications. Deep learning models can often misidentify OOD samples as in-distribution (ID) samples. This vulnerability…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Sudarshan Regmi

The complex and dynamic real-world clinical environment demands reliable deep learning (DL) systems. Out-of-distribution (OOD) detection plays a critical role in enhancing the reliability and generalizability of DL models when encountering…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Jiangbei Yue , Darren Treanor , Venkataraman Subramanian , Sharib Ali

Recently, we have witnessed generative retrieval increasingly gaining attention in the information retrieval (IR) field, which retrieves documents by directly generating their identifiers. So far, much effort has been devoted to developing…

Information Retrieval · Computer Science 2023-06-23 Yu-An Liu , Ruqing Zhang , Jiafeng Guo , Wei Chen , Xueqi Cheng

Detecting Out-of-Distribution (OOD) sensory data and covariate distribution shift aims to identify new test examples with different high-level image statistics to the captured, normal and In-Distribution (ID) set. Existing OOD detection…

Computer Vision and Pattern Recognition · Computer Science 2024-10-10 Christiaan Viviers , Amaan Valiuddin , Francisco Caetano , Lemar Abdi , Lena Filatova , Peter de With , Fons van der Sommen

Deep neural networks (DNNs) have the potential to power many biomedical workflows, but training them on truly representative, IID datasets is often infeasible. Most models instead rely on biased or incomplete data, making them prone to…

Machine Learning · Computer Science 2025-10-16 Yasith Jayawardana , Dineth Jayakody , Sampath Jayarathna , Dushan N. Wadduwage

Recent object detectors have achieved impressive accuracy in identifying objects seen during training. However, real-world deployment often introduces novel and unexpected objects, referred to as out-of-distribution (OOD) objects, posing…

Machine Learning · Computer Science 2025-11-20 Quang-Huy Nguyen , Jin Peng Zhou , Zhenzhen Liu , Khanh-Huyen Bui , Kilian Q. Weinberger , Wei-Lun Chao , Dung D. Le

This work introduces MiDi, a novel diffusion model for jointly generating molecular graphs and their corresponding 3D arrangement of atoms. Unlike existing methods that rely on predefined rules to determine molecular bonds based on the 3D…

Machine Learning · Computer Science 2023-06-06 Clement Vignac , Nagham Osman , Laura Toni , Pascal Frossard

Graph neural networks (GNNs) have been demonstrated to perform well in graph representation learning, but always lacking in generalization capability when tackling out-of-distribution (OOD) data. Graph invariant learning methods, backed by…

Machine Learning · Computer Science 2023-12-19 Tianrui Jia , Haoyang Li , Cheng Yang , Tao Tao , Chuan Shi

Out-of-distribution (OOD) detection is essential for the reliability of ML models. Most existing methods for OOD detection learn a fixed decision criterion from a given in-distribution dataset and apply it universally to decide if a data…

Machine Learning · Computer Science 2023-11-29 YiFan Zhang , Xue Wang , Tian Zhou , Kun Yuan , Zhang Zhang , Liang Wang , Rong Jin , Tieniu Tan

The crux of effective out-of-distribution (OOD) detection lies in acquiring a robust in-distribution (ID) representation, distinct from OOD samples. While previous methods predominantly leaned on recognition-based techniques for this…

Computer Vision and Pattern Recognition · Computer Science 2024-01-08 Jingyao Li , Pengguang Chen , Shaozuo Yu , Shu Liu , Jiaya Jia

Out-of-distribution (OOD) detection is crucial for enhancing the generalization of AI models used in mammogram screening. Given the challenge of limited prior knowledge about OOD samples in external datasets, unsupervised generative…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Zhemin Zhang , Bhavika Patel , Bhavik Patel , Imon Banerjee

Encouraging progress has been made towards Visual Question Answering (VQA) in recent years, but it is still challenging to enable VQA models to adaptively generalize to out-of-distribution (OOD) samples. Intuitively, recompositions of…

Computer Vision and Pattern Recognition · Computer Science 2021-10-05 Jingjing Jiang , Ziyi Liu , Yifan Liu , Zhixiong Nan , Nanning Zheng
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