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The Susceptible-Infectious-Recovered (SIR) equations and their extensions comprise a commonly utilized set of models for understanding and predicting the course of an epidemic. In practice, it is of substantial interest to estimate the…

Applications · Statistics 2025-05-07 Omar Melikechi , Alexander L. Young , Tao Tang , Trevor Bowman , David Dunson , James Johndrow

The Time Since Infection (TSI) models, which use disease surveillance data to model infectious diseases, have become increasingly popular due to their flexibility and capacity to address complex disease control questions. However, a notable…

Methodology · Statistics 2025-01-10 Jiasheng Shi , Yizhao Zhou , Jing Huang

The mathematical interpretation of interventions for the mitigation of epidemics and pandemics in the literature often involves finding the optimal time to initiate an intervention and/or the use of infections to manage impact. Whilst these…

Populations and Evolution · Quantitative Biology 2023-05-17 James Van Yperen , Eduard Campillo-Funollet , Rebecca Inkpen , Anjum Memon , Anotida Madzvamuse

The integration of empirical data in computational frameworks to model the spread of infectious diseases poses challenges that are becoming pressing with the increasing availability of high-resolution information on human mobility and…

Populations and Evolution · Quantitative Biology 2013-04-24 Anna Machens , Francesco Gesualdo , Caterina Rizzo , Alberto E Tozzi , Alain Barrat , Ciro Cattuto

A standard model for epidemics is the SIR model on a graph. We introduce a simple algorithm that uses the early infection times from a sample path of the SIR model to estimate the parameters this model, and we provide a performance…

Information Theory · Computer Science 2020-08-11 Charles Clum , Dustin G. Mixon

In this work, we review the figures used to characterize an epidemic outbreak most. Particular attention is drawn to epidemic spreading at time-varying transition rates. A time-varying SIR-like model is used to describe the epidemic…

Populations and Evolution · Quantitative Biology 2020-11-06 Hernán De Battista , José García-Clúa , Sebastián Nuñez , Fernando Inthamoussou , Fabricio Garelli

We propose an extension of the classical susceptible infectious recovered (SIR) model that incorporates the effects of spatial propagation of an epidemic through a small number of additional compartments. The model is designed to capture…

Numerical Analysis · Mathematics 2026-03-02 M. Soledad Aronna , Mariana Bergonzi , Ernesto Kofman

Susceptible-Exposed-Infectious-Recovered (SEIR) models with inter-individual variation in susceptibility or exposure to infection were proposed early in the COVID-19 pandemic as a potential element of the mathematical/statistical toolset…

Applications · Statistics 2025-10-28 Ibrahim Mohammed , Chris Robertson , M. Gabriela M. Gomes

Many disease models focus on characterizing the underlying transmission mechanism but make simple, possibly naive assumptions about how infections are reported. In this note, we use a simple deterministic Susceptible-Infected-Removed (SIR)…

Populations and Evolution · Quantitative Biology 2019-11-28 Sang Woo Park , Benjamin M. Bolker

As global living standards improve and medical technology advances, many infectious diseases have been effectively controlled. However, certain diseases, such as the recent COVID-19 pandemic, continue to pose significant threats to public…

Numerical Analysis · Mathematics 2025-02-24 Ayesha Baig , Li Zhouxin

Infectious disease epidemiologists routinely fit stochastic epidemic models to time series data to elucidate infectious disease dynamics, evaluate interventions, and forecast epidemic trajectories. To improve computational tractability,…

Modeling epidemic dynamics plays an important role in studying how diseases spread, predicting their future course, and designing strategies to control them. In this letter, we introduce a model of SIR (susceptible-infected-removed) type…

Populations and Evolution · Quantitative Biology 2013-12-17 Li Chen , Fakhteh Ghanbarnejad , Weiran Cai , Peter Grassberger

Using the classical Susceptible-Infected-Recovered epidemiological model, an analytical formula is derived for the number of beds occupied by Covid-19 patients. The analytical curve is fitted to data in Belgium, France, New York City and…

Populations and Evolution · Quantitative Biology 2021-02-22 Gregory Kozyreff

The last decade saw the advent of increasingly realistic epidemic models that leverage on the availability of highly detailed census and human mobility data. Data-driven models aim at a granularity down to the level of households or single…

Populations and Evolution · Quantitative Biology 2011-08-10 Nicola Perra , Duygu Balcan , Bruno Gonçalves , Alessandro Vespignani

We propose an SIR epidemic model coupled with opinion dynamics to study an epidemic and opinions spreading in a network of communities. Our model couples networked SIR epidemic dynamics with opinions towards the severity of the epidemic,…

Systems and Control · Electrical Eng. & Systems 2025-06-23 Baike She , Humphrey C. H. Leung , Shreyas Sundaram , Philip E. Paré

Accurate epidemic forecasting is critical for informing public health decisions and timely interventions. While Physics-Informed Neural Networks have shown promise in various scientific domains, their potential application to real-time…

Physics and Society · Physics 2026-05-20 Martina Rama , Gabriele Santin , Giulia Cencetti , Michele Tizzoni , Bruno Lepri

Accurate forecasts of the number of newly infected people during an epidemic are critical for making effective timely decisions. This paper addresses this challenge using the SIMLR model, which incorporates machine learning (ML) into the…

Machine Learning · Computer Science 2021-06-04 Roberto Vega , Leonardo Flores , Russell Greiner

We develop a multiple compartment Susceptible-Infected-Recovered (SIR) model to analyze the spread of several infectious diseases through different geographic areas. Additionally, we propose a data-quality sensitive optimization framework…

Populations and Evolution · Quantitative Biology 2019-06-21 Inbar Seroussi , Nir Levy , Daniela Paolotti , Nir Sochen , Elad Yom-Tov

Understanding infectious disease spread remains a critical public health challenge, particularly given the interplay between household dynamics and community transmission patterns. Traditional epidemiological models often oversimplify these…

Populations and Evolution · Quantitative Biology 2026-01-21 Houda Yaqine , Christiane Fuchs

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

Methodology · Statistics 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang
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