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In clinical applications, the utility of segmentation models is often based on the accuracy of derived downstream metrics such as organ size, rather than by the pixel-level accuracy of the segmentation masks themselves. Thus, uncertainty…

Image and Video Processing · Electrical Eng. & Systems 2026-03-03 Matt Y. Cheung , Ashok Veeraraghavan , Guha Balakrishnan

Image restoration problems are often ill-posed, leading to significant uncertainty in reconstructed images. Accurately quantifying this uncertainty is essential for the reliable interpretation of reconstructed images. However, image…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Bernardin Tamo Amougou , Marcelo Pereyra , Barbara Pascal

Most image restoration problems are ill-conditioned or ill-posed and hence involve significant uncertainty. Quantifying this uncertainty is crucial for reliably interpreting experimental results, particularly when reconstructed images…

Computer Vision and Pattern Recognition · Computer Science 2025-02-10 Jasper M. Everink , Bernardin Tamo Amougou , Marcelo Pereyra

The reconstruction of an unknown quantity from noisy measurements is a mathematical problem relevant in most applied sciences, for example, in medical imaging, radar inverse scattering, or astronomy. This underlying mathematical problem is…

Optimization and Control · Mathematics 2025-10-14 Nina M. Gottschling , David Iagaru , Jakob Gawlikowski , Ioannis Sgouralis

We develop confidence sets which provide spatial uncertainty guarantees for the output of a black-box machine learning model designed for image segmentation. To do so we adapt conformal inference to the imaging setting, obtaining thresholds…

Machine Learning · Statistics 2024-10-10 Samuel Davenport

In critical decision support systems based on medical imaging, the reliability of AI-assisted decision-making is as relevant as predictive accuracy. Although deep learning models have demonstrated significant accuracy, they frequently…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Hua Xu , Julián D. Arias-Londoño , Juan I. Godino-Llorente

Deep learning algorithms have recently shown to be a successful tool in estimating parameters of statistical models for which simulation is easy, but likelihood computation is challenging. But the success of these approaches depends on…

Machine Learning · Statistics 2024-02-20 Amanda Lenzi , Haavard Rue

We present a principled framework for confidence estimation in computed tomography (CT) reconstruction. Based on the sequential likelihood mixing framework (Kirschner et al., 2025), we establish confidence regions with theoretical coverage…

Machine Learning · Computer Science 2026-02-06 Matteo Gätzner , Johannes Kirschner

The increasing use of generative ML foundation models for image restoration tasks such as super-resolution calls for robust and interpretable uncertainty quantification methods. We address this need by presenting a novel approach based on…

Computer Vision and Pattern Recognition · Computer Science 2025-11-05 Eduardo Adame , Daniel Csillag , Guilherme Tegoni Goedert

This work focuses on assessing the information-theoretic limits of scene parameter estimation in plenoptic imaging systems. A general framework to compute lower bounds on the parameter estimation error from noisy plenoptic observations is…

Image and Video Processing · Electrical Eng. & Systems 2026-02-03 Abhinav V. Sambasivan , Liam J. Coulter , Richard G. Paxman , Jarvis D. Haupt

Inverse problems, such as accelerated MRI reconstruction, are ill-posed and an infinite amount of possible and plausible solutions exist. This may not only lead to uncertainty in the reconstructed image but also in downstream tasks such as…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 Jan Nikolas Morshuis , Matthias Hein , Christian F. Baumgartner

Uncertainty quantification plays an important role in achieving trustworthy and reliable learning-based computational imaging. Recent advances in generative modeling and Bayesian neural networks have enabled the development of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-07 Canberk Ekmekci , Mujdat Cetin

Deep learning has the potential to automate many clinically useful tasks in medical imaging. However translation of deep learning into clinical practice has been hindered by issues such as lack of the transparency and interpretability in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-04 Charles Lu , Andreanne Lemay , Ken Chang , Katharina Hoebel , Jayashree Kalpathy-Cramer

Image segmentation is a challenging task influenced by multiple sources of uncertainty, such as the data labeling process or the sampling of training data. In this paper we focus on binary segmentation and address these challenges using…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Luca Mossina , Corentin Friedrich

The need for tomographic reconstruction from sparse measurements arises when the measurement process is potentially harmful, needs to be rapid, or is uneconomical. In such cases, prior information from previous longitudinal scans of the…

Computer Vision and Pattern Recognition · Computer Science 2018-12-31 Preeti Gopal , Sharat Chandran , Imants Svalbe , Ajit Rajwade

Magnetic Resonance Imaging (MRI) offers unparalleled soft-tissue contrast but is fundamentally limited by long acquisition times. While deep learning-based accelerated MRI can dramatically shorten scan times, the reconstruction from…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Paul Fischer , Jan Nikolas Morshuis , Thomas Küstner , Christian Baumgartner

Reliable confidence measures of metrics derived from medical imaging reconstruction pipelines would improve the standard of decision-making in many clinical workflows. Conformal Prediction (CP) provides a robust framework for producing…

Computational image reconstruction algorithms generally produce a single image without any measure of uncertainty or confidence. Regularized Maximum Likelihood (RML) and feed-forward deep learning approaches for inverse problems typically…

Machine Learning · Computer Science 2020-12-18 He Sun , Katherine L. Bouman

Black-box machine learning models are now routinely used in high-risk settings, like medical diagnostics, which demand uncertainty quantification to avoid consequential model failures. Conformal prediction is a user-friendly paradigm for…

Machine Learning · Computer Science 2022-12-08 Anastasios N. Angelopoulos , Stephen Bates

Deep unrolling is an emerging deep learning-based image reconstruction methodology that bridges the gap between model-based and purely deep learning-based image reconstruction methods. Although deep unrolling methods achieve…

Image and Video Processing · Electrical Eng. & Systems 2022-12-21 Canberk Ekmekci , Mujdat Cetin
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