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Related papers: Towards Large-Scale Training of Pathology Foundati…

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Foundation models, first introduced in 2021, refer to large-scale pretrained models (e.g., large language models (LLMs) and vision-language models (VLMs)) that learn from extensive unlabeled datasets through unsupervised methods, enabling…

Pathological diagnosis remains the definitive standard for identifying tumors. The rise of multimodal large models has simplified the process of integrating image analysis with textual descriptions. Despite this advancement, the substantial…

Computer Vision and Pattern Recognition · Computer Science 2024-08-14 Xiaomin Wu , Rui Xu , Pengchen Wei , Wenkang Qin , Peixiang Huang , Ziheng Li , Lin Luo

Inevitable domain and task discrepancies in real-world scenarios can impair the generalization performance of the pre-trained deep models for medical data. Therefore, we audaciously propose that we should build a general-purpose medical AI…

Computer Vision and Pattern Recognition · Computer Science 2023-03-14 Huahui Yi , Ziyuan Qin , Qicheng Lao , Wei Xu , Zekun Jiang , Dequan Wang , Shaoting Zhang , Kang Li

Despite their successes in vision and language, foundation models have stumbled in pathology, revealing low accuracy, instability, and heavy computational demands. These shortcomings stem not from tuning problems but from deeper conceptual…

Artificial Intelligence · Computer Science 2026-04-21 Hamid R. Tizhoosh

Foundation Models (FMs) serve as a general class for the development of artificial intelligence systems, offering broad potential for generalization across a spectrum of downstream tasks. Despite extensive research into self-supervised…

Machine Learning · Computer Science 2024-06-17 Yuhao Xu , Xinqi Liu , Keyu Duan , Yi Fang , Yu-Neng Chuang , Daochen Zha , Qiaoyu Tan

Personalized diagnoses have not been possible due to sear amount of data pathologists have to bear during the day-to-day routine. This lead to the current generalized standards that are being continuously updated as new findings are…

Computer Vision and Pattern Recognition · Computer Science 2021-10-27 Jialun Wu , Zeyu Gao , Haichuan Zhang , Ruonan Zhang , Tieliang Gong , Chunbao Wang , Chen Li

To handle the large scale of whole slide images in computational pathology, most approaches first tessellate the images into smaller patches, extract features from these patches, and finally aggregate the feature vectors with…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Benedikt Roth , Valentin Koch , Sophia J. Wagner , Julia A. Schnabel , Carsten Marr , Tingying Peng

Foundation models (FM) have demonstrated remarkable performance across a wide range of tasks (especially in the fields of natural language processing and computer vision), primarily attributed to their ability to comprehend instructions and…

Artificial Intelligence · Computer Science 2025-02-11 Hongling Zheng , Li Shen , Anke Tang , Yong Luo , Han Hu , Bo Du , Yonggang Wen , Dacheng Tao

Large pre-trained models with their numerous model parameters and extensive training datasets have shown excellent performance in various tasks. Many publicly available medical image datasets do not have a sufficient amount of data so there…

Image and Video Processing · Electrical Eng. & Systems 2024-03-12 Jianhao Xie , Ziang Zhang , Guibo Luo , Yuesheng Zhu

The growing demand for accurate and equitable AI models in digital dermatology faces a significant challenge: the lack of diverse, high-quality labeled data. In this work, we investigate the potential of domain-specific foundation models…

Following its success for vision and text, the "foundation model" (FM) paradigm -- pretraining large models on massive data, then fine-tuning on target tasks -- has rapidly expanded to domains in the sciences, engineering, healthcare, and…

Machine Learning · Computer Science 2025-03-24 Zongzhe Xu , Ritvik Gupta , Wenduo Cheng , Alexander Shen , Junhong Shen , Ameet Talwalkar , Mikhail Khodak

Computational pathology (CPath) has shown great potential in mining actionable insights from Whole Slide Images (WSIs). Deep Learning (DL) has been at the center of modern CPath, and while it delivers unprecedented performance, it is also…

Quantitative Methods · Quantitative Biology 2025-07-31 Gianluca Carloni , Biagio Brattoli , Seongho Keum , Jongchan Park , Taebum Lee , Chang Ho Ahn , Sergio Pereira

Whole slide image (WSI) analysis has emerged as an increasingly essential technique in computational pathology. Recent advances in the pathology foundation models (FMs) have demonstrated significant advantages in deriving meaningful…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Zhidong Yang , Xiuhui Shi , Wei Ba , Zhigang Song , Haijing Luan , Taiyuan Hu , Senlin Lin , Jiguang Wang , Shaohua Kevin Zhou , Rui Yan

Deep learning-based computer-aided diagnosis is gradually deployed to review and analyze medical images. However, this paradigm is restricted in real-world clinical applications due to the poor robustness and generalization. The issue is…

Computer Vision and Pattern Recognition · Computer Science 2022-03-22 Yurong Chen

Foundation models are rapidly being developed for computational pathology applications. However, it remains an open question which factors are most important for downstream performance with data scale and diversity, model size, and training…

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

As the rapid development of computer vision and the emergence of powerful network backbones and architectures, the application of deep learning in medical imaging has become increasingly significant. Unlike natural images, medical images…

Image and Video Processing · Electrical Eng. & Systems 2026-04-10 Guoqing Zhang , Jingyun Yang , Yang Li

Foundation models are widely employed in medical image analysis, due to their high adaptability and generalizability for downstream tasks. With the increasing number of foundation models being released, model selection has become an…

Image and Video Processing · Electrical Eng. & Systems 2025-01-27 Fuping Wu , Bartlomiej W. Papiez

Histopathological images are widely used for the analysis of diseased (tumor) tissues and patient treatment selection. While the majority of microscopy image processing was previously done manually by pathologists, recent advances in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-12 Andrey Ignatov , Josephine Yates , Valentina Boeva

Histopathology tissue analysis is considered the gold standard in cancer diagnosis and prognosis. Given the large size of these images and the increase in the number of potential cancer cases, an automated solution as an aid to…

Image and Video Processing · Electrical Eng. & Systems 2020-11-19 Mahendra Khened , Avinash Kori , Haran Rajkumar , Balaji Srinivasan , Ganapathy Krishnamurthi