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A common solution to the semantic heterogeneity problem is to perform knowledge graph (KG) extension exploiting the information encoded in one or more candidate KGs, where the alignment between the reference KG and candidate KGs is…

Artificial Intelligence · Computer Science 2024-07-09 Daqian Shi , Xiaoyue Li , Fausto Giunchiglia

Identification of disease genes, which are a set of genes associated with a disease, plays an important role in understanding and curing diseases. In this paper, we present a biomedical knowledge graph designed specifically for this…

Cancer remains one of the most challenging diseases to treat in the medical field. Machine learning has enabled in-depth analysis of rich multi-omics profiles and medical imaging for cancer diagnosis and prognosis. Despite these…

Machine Learning · Computer Science 2024-01-15 Lingchao Mao , Hairong Wang , Leland S. Hu , Nhan L Tran , Peter D Canoll , Kristin R Swanson , Jing Li

Numeric values associated to edges of a knowledge graph have been used to represent uncertainty, edge importance, and even out-of-band knowledge in a growing number of scenarios, ranging from genetic data to social networks. Nevertheless,…

Artificial Intelligence · Computer Science 2021-05-19 Sumit Pai , Luca Costabello

Knowledge graph (KG) plays an increasingly important role to improve the recommendation performance and interpretability. A recent technical trend is to design end-to-end models based on information propagation schemes. However, existing…

Information Retrieval · Computer Science 2022-04-12 Yuntao Du , Xinjun Zhu , Lu Chen , Baihua Zheng , Yunjun Gao

Large-scale population-based studies in medicine are a key resource towards better diagnosis, monitoring, and treatment of diseases. They also serve as enablers of clinical decision support systems, in particular Computer Aided Diagnosis…

Machine Learning · Computer Science 2022-03-01 Gerome Vivar , Anees Kazi , Hendrik Burwinkel , Andreas Zwergal , Nassir Navab , Seyed-Ahmad Ahmadi

Knowledge graph (KG) entity typing aims at inferring possible missing entity type instances in KG, which is a very significant but still under-explored subtask of knowledge graph completion. In this paper, we propose a novel approach for KG…

Computation and Language · Computer Science 2020-07-22 Yu Zhao , Anxiang Zhang , Ruobing Xie , Kang Liu , Xiaojie Wang

Predicting genetic mutations from whole slide images is indispensable for cancer diagnosis. However, existing work training multiple binary classification models faces two challenges: (a) Training multiple binary classifiers is inefficient…

Computer Vision and Pattern Recognition · Computer Science 2024-06-06 Gexin Huang , Chenfei Wu , Mingjie Li , Xiaojun Chang , Ling Chen , Ying Sun , Shen Zhao , Xiaodan Liang , Liang Lin

Knowledge graph embeddings are now a widely adopted approach to knowledge representation in which entities and relationships are embedded in vector spaces. In this chapter, we introduce the reader to the concept of knowledge graph…

Artificial Intelligence · Computer Science 2020-05-01 Federico Bianchi , Gaetano Rossiello , Luca Costabello , Matteo Palmonari , Pasquale Minervini

Knowledge graph-based dialogue systems can narrow down knowledge candidates for generating informative and diverse responses with the use of prior information, e.g., triple attributes or graph paths. However, most current knowledge graph…

Computation and Language · Computer Science 2020-04-21 Hongcai Xu , Junpeng Bao , Junqing Wang

Learning low-dimensional embeddings of knowledge graphs is a powerful approach used to predict unobserved or missing edges between entities. However, an open challenge in this area is developing techniques that can go beyond simple edge…

Social and Information Networks · Computer Science 2019-10-30 William L. Hamilton , Payal Bajaj , Marinka Zitnik , Dan Jurafsky , Jure Leskovec

Existing data-centric methods for protein science generally cannot sufficiently capture and leverage biology knowledge, which may be crucial for many protein tasks. To facilitate research in this field, we create ProteinKG65, a knowledge…

Quantitative Methods · Quantitative Biology 2022-11-15 Siyuan Cheng , Xiaozhuan Liang , Zhen Bi , Huajun Chen , Ningyu Zhang

Motivation: Biomedical knowledge graphs (KGs) are crucial for drug discovery and disease understanding, yet their completion and reasoning are challenging. Knowledge Embedding (KE) methods capture global semantics but struggle with dynamic…

Artificial Intelligence · Computer Science 2025-07-23 Yitong Lin , Jiaying He , Jiahe Chen , Xinnan Zhu , Jianwei Zheng , Tao Bo

Graph neural networks (GNNs) are powerful machine learning models designed to handle irregularly structured data. However, their generic design often proves inadequate for analyzing brain connectomes in Alzheimer's Disease (AD),…

Machine Learning · Computer Science 2024-12-10 Zhepeng Wang , Runxue Bao , Yawen Wu , Guodong Liu , Lei Yang , Liang Zhan , Feng Zheng , Weiwen Jiang , Yanfu Zhang

Vector representations have been pivotal in advancing natural language processing (NLP), with prior research focusing on embedding techniques for mathematical expressions using mathematically equivalent formulations. While effective, these…

Machine Learning · Computer Science 2025-03-11 Hongbo Zheng , Suyuan Wang , Neeraj Gangwar , Nickvash Kani

Knowledge graphs (KGs) play a vital role in enhancing search results and recommendation systems. With the rapid increase in the size of the KGs, they are becoming inaccuracy and incomplete. This problem can be solved by the knowledge graph…

Machine Learning · Computer Science 2024-08-06 Wanxu Wei , Yitong Song , Bin Yao

In this paper, we consider the problem of disease diagnosis. Unlike the conventional learning paradigm that treats labels independently, we propose a knowledge-enhanced framework, that enables training visual representation with the…

Computer Vision and Pattern Recognition · Computer Science 2023-02-28 Chaoyi Wu , Xiaoman Zhang , Yanfeng Wang , Ya Zhang , Weidi Xie

International initiatives such as METABRIC (Molecular Taxonomy of Breast Cancer International Consortium) have collected several multigenomic and clinical data sets to identify the undergoing molecular processes taking place throughout the…

Machine Learning · Computer Science 2022-11-29 Teodora Reu

Knowledge Graph Embeddings (KGE) have become a quite popular class of models specifically devised to deal with ontologies and graph structure data, as they can implicitly encode statistical dependencies between entities and relations in a…

Artificial Intelligence · Computer Science 2023-03-27 Michelangelo Diligenti , Francesco Giannini , Stefano Fioravanti , Caterina Graziani , Moreno Falaschi , Giuseppe Marra

Knowledge Graphs (KGs) and their machine learning counterpart, Knowledge Graph Embedding Models (KGEMs), have seen ever-increasing use in a wide variety of academic and applied settings. In particular, KGEMs are typically applied to KGs to…

Machine Learning · Computer Science 2024-12-16 Jeffrey Sardina , John D. Kelleher , Declan O'Sullivan