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Despite their improved capabilities in generation and reasoning, adapting large language models (LLMs) to the biomedical domain remains challenging due to their immense size and corporate privacy. In this work, we propose MedAdapter, a…

Computation and Language · Computer Science 2024-10-07 Wenqi Shi , Ran Xu , Yuchen Zhuang , Yue Yu , Haotian Sun , Hang Wu , Carl Yang , May D. Wang

The advent of Large Language Models (LLM) has reformed the Automatic Speech Recognition (ASR). Prompting LLM with audio embeddings to generate transcriptions becomes the new state-of-the-art ASR. Despite LLMs being trained with an extensive…

Computation and Language · Computer Science 2024-12-11 Yingyi Ma , Zhe Liu , Ozlem Kalinli

Protein language models (PLMs) have shown promise in improving the understanding of protein sequences, contributing to advances in areas such as function prediction and protein engineering. However, training these models from scratch…

Machine Learning · Computer Science 2024-12-19 Shivasankaran Vanaja Pandi , Bharath Ramsundar

Prompt engineering, as an efficient and effective way to leverage Large Language Models (LLM), has drawn a lot of attention from the research community. The existing research primarily emphasizes the importance of adapting prompts to…

Computation and Language · Computer Science 2024-07-08 Yuyan Chen , Zhihao Wen , Ge Fan , Zhengyu Chen , Wei Wu , Dayiheng Liu , Zhixu Li , Bang Liu , Yanghua Xiao

Parameter-efficient fine-tuning (PEFT) of powerful pre-trained models for complex downstream tasks has proven effective in vision and language processing, yet this paradigm remains unexplored in scientific machine learning, where the…

Machine Learning · Computer Science 2025-10-20 Hangwei Zhang , Chun Kang , Yan Wang , Difan Zou

Pre-trained language models (PTLMs) acquire domain-independent linguistic knowledge through pre-training with massive textual resources. Additional pre-training is effective in adapting PTLMs to domains that are not well covered by the…

Computation and Language · Computer Science 2021-09-20 Kosuke Nishida , Kyosuke Nishida , Sen Yoshida

Automatic Speech Recognition (ASR) systems have found their use in numerous industrial applications in very diverse domains creating a need to adapt to new domains with small memory and deployment overhead. In this work, we introduce…

Computation and Language · Computer Science 2022-07-25 Saket Dingliwal , Ashish Shenoy , Sravan Bodapati , Ankur Gandhe , Ravi Teja Gadde , Katrin Kirchhoff

Large language models (LMs) are typically adapted to improve performance on new contexts (\eg text prompts that define new tasks or domains) through fine-tuning or prompting. However, there is an accuracy compute tradeoff -- fine-tuning…

Machine Learning · Computer Science 2024-11-12 Tong Chen , Hao Fang , Patrick Xia , Xiaodong Liu , Benjamin Van Durme , Luke Zettlemoyer , Jianfeng Gao , Hao Cheng

Parameter-efficient tuning (PET) methods fit pre-trained language models (PLMs) to downstream tasks by either computing a small compressed update for a subset of model parameters, or appending and fine-tuning a small number of new model…

Computation and Language · Computer Science 2023-05-29 Neal Lawton , Anoop Kumar , Govind Thattai , Aram Galstyan , Greg Ver Steeg

Pretrained language models (PLMs) are today the primary model for natural language processing. Despite their impressive downstream performance, it can be difficult to apply PLMs to new languages, a barrier to making their capabilities…

Computation and Language · Computer Science 2024-01-15 Yihong Chen , Kelly Marchisio , Roberta Raileanu , David Ifeoluwa Adelani , Pontus Stenetorp , Sebastian Riedel , Mikel Artetxe

Adapting Large Language Models (LLMs) to a continuous stream of tasks is a critical yet challenging endeavor. While Parameter-Efficient Fine-Tuning (PEFT) methods have become a standard for this, they face a fundamental dilemma in continual…

Machine Learning · Computer Science 2025-11-11 Haeyong Kang

Alignment of Large Language Models (LLMs) typically relies on Reinforcement Learning from Human Feedback (RLHF) with gradient-based optimizers such as Proximal Policy Optimization (PPO) or Group Relative Policy Optimization (GRPO). While…

Large Language Models (LLMs) have demonstrated remarkable efficacy in text embedding, yet current adaptation methods like LoRA face significant bottlenecks in computational efficiency and cross-architecture transferability. Whenever a new…

Computation and Language · Computer Science 2026-05-28 Yu-Che Tsai , Kuan-Yu Chen , Yuan-Hao Chen , Yu-Han Chang , Ching-Yu Tsai , Yu-Hsiang Chuang , Shou-De Lin

In the arena of language model fine-tuning, the traditional approaches, such as Domain-Adaptive Pretraining (DAPT) and Task-Adaptive Pretraining (TAPT), although effective, but computational intensive. This research introduces a novel…

Computation and Language · Computer Science 2024-05-10 Keyu Chen , Yuan Pang , Zi Yang

Large pre-trained vision-language (VL) models have shown significant promise in adapting to various downstream tasks. However, fine-tuning the entire network is challenging due to the massive number of model parameters. To address this…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Jingchen Sun , Jiayu Qin , Zihao Lin , Changyou Chen

Pre-trained LLMs have demonstrated substantial capabilities across a range of conventional natural language processing (NLP) tasks, such as summarization and entity recognition. In this paper, we explore the application of LLMs in the…

Quantitative Methods · Quantitative Biology 2024-08-14 Kamyar Zeinalipour , Neda Jamshidi , Monica Bianchini , Marco Maggini , Marco Gori

Large Language Models (LLMs) have shown high capabilities in several software development-related tasks such as program repair, documentation, code refactoring, debugging, and testing. However, training these models requires massive amount…

Software Engineering · Computer Science 2025-06-10 Meghdad Dehghan , Jie JW Wu , Fatemeh H. Fard , Ali Ouni

Large Language Models (LLMs) have demonstrated exceptional abilities across a broad range of language-related tasks, including generating solutions to complex reasoning problems. An effective technique to enhance LLM performance is…

Computation and Language · Computer Science 2024-12-25 Shuzhang Cai , Twumasi Mensah-Boateng , Xander Kuksov , Jing Yuan , Shaojie Tang

Protein structure prediction often hinges on multiple sequence alignments (MSAs), which underperform on low-homology and orphan proteins. We introduce PLAME, a lightweight MSA design framework that leverages evolutionary embeddings from…

Machine Learning · Computer Science 2025-09-29 Hanqun Cao , Xinyi Zhou , Zijun Gao , Chenyu Wang , Xin Gao , Zhi Zhang , Cesar de la Fuente-Nunez , Chunbin Gu , Ge Liu , Pheng-Ann Heng

Different languages have distinct phonetic systems and vary in their prosodic features making it challenging to develop a Text-to-Speech (TTS) model that can effectively synthesise speech in multilingual settings. Furthermore, TTS…

Computation and Language · Computer Science 2024-06-26 Yingting Li , Ambuj Mehrish , Bryan Chew , Bo Cheng , Soujanya Poria