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Software Engineering (SE) Pre-trained Language Models (PLMs), such as CodeBERT, are pre-trained on large code corpora, and their learned knowledge has shown success in transferring into downstream tasks (e.g., code clone detection) through…

Software Engineering · Computer Science 2024-02-07 Iman Saberi , Fatemeh Fard , Fuxiang Chen

Small language models (SLMs) have attracted considerable attention from both academia and industry due to their broad range of applications in edge devices. To obtain SLMs with strong performance, conventional approaches either pre-train…

Machine Learning · Computer Science 2025-11-17 Rui Pan , Shivanshu Shekhar , Boyao Wang , Shizhe Diao , Jipeng Zhang , Xingyuan Pan , Renjie Pi , Tong Zhang

Self-supervised learning has emerged as a key approach for learning generic representations from speech data. Despite promising results in downstream tasks such as speech recognition, speaker verification, and emotion recognition, a…

Computation and Language · Computer Science 2024-08-01 Nakamasa Inoue , Shinta Otake , Takumi Hirose , Masanari Ohi , Rei Kawakami

Protein language models (pLMs) pre-trained on vast protein sequence databases excel at various downstream tasks but often lack the structural knowledge essential for some biological applications. To address this, we introduce a method to…

Cross-lingual speech adaptation aims to solve the problem of leveraging multiple rich-resource languages to build models for a low-resource target language. Since the low-resource language has limited training data, speech recognition…

Computation and Language · Computer Science 2021-12-21 Wenxin Hou , Han Zhu , Yidong Wang , Jindong Wang , Tao Qin , Renjun Xu , Takahiro Shinozaki

Fine-tuning of self-supervised models is a powerful transfer learning method in a variety of fields, including speech processing, since it can utilize generic feature representations obtained from large amounts of unlabeled data.…

Multimedia · Computer Science 2022-12-07 Shinta Otake , Rei Kawakami , Nakamasa Inoue

The success of large language models (LLMs), like GPT-4 and ChatGPT, has led to the development of numerous cost-effective and accessible alternatives that are created by finetuning open-access LLMs with task-specific data (e.g.,…

Computation and Language · Computer Science 2023-10-10 Zhiqiang Hu , Lei Wang , Yihuai Lan , Wanyu Xu , Ee-Peng Lim , Lidong Bing , Xing Xu , Soujanya Poria , Roy Ka-Wei Lee

In this study, we aim to explore efficient tuning methods for speech self-supervised learning. Recent studies show that self-supervised learning (SSL) can learn powerful representations for different speech tasks. However, fine-tuning…

Audio and Speech Processing · Electrical Eng. & Systems 2023-01-31 Zih-Ching Chen , Chin-Lun Fu , Chih-Ying Liu , Shang-Wen Li , Hung-yi Lee

Supervised fine-tuning (SFT) is a standard approach for adapting large language models to specialized domains, yet its application to protein sequence modeling and protein language models (PLMs) remains ad hoc. This is in part because…

Machine Learning · Computer Science 2025-12-11 Amin Tavakoli , Raswanth Murugan , Ozan Gokdemir , Arvind Ramanathan , Frances Arnold , Anima Anandkumar

Proteins, as essential biomolecules, play a central role in biological processes, including metabolic reactions and DNA replication. Accurate prediction of their properties and functions is crucial in biological applications. Recent…

Computation and Language · Computer Science 2025-05-30 Wei Wu , Chao Wang , Liyi Chen , Mingze Yin , Yiheng Zhu , Kun Fu , Jieping Ye , Hui Xiong , Zheng Wang

Proteins adopt multiple structural conformations to perform their diverse biological functions, and understanding these conformations is crucial for advancing drug discovery. Traditional physics-based simulation methods often struggle with…

Biomolecules · Quantitative Biology 2025-03-14 Jiarui Lu , Xiaoyin Chen , Stephen Zhewen Lu , Chence Shi , Hongyu Guo , Yoshua Bengio , Jian Tang

Protein language models (PLMs) have revolutionised computational biology through their ability to generate powerful sequence representations for diverse prediction tasks. However, their black-box nature limits biological interpretation and…

Biomolecules · Quantitative Biology 2025-04-11 Jan van Eck , Dea Gogishvili , Wilson Silva , Sanne Abeln

While integrating speech encoder with LLM requires substantial data and resources, use cases face limitations due to insufficient availability. To address this, we propose a solution with a parameter-efficient adapter that converts speech…

Computation and Language · Computer Science 2025-09-08 Jaekwon Yoo , Kunal Chandiramani , Divya Tadimeti , Abenezer Girma , Chandra Dhir

Protein language models (PLMs) have demonstrated remarkable success in protein modeling and design, yet their internal mechanisms for predicting structure and function remain poorly understood. Here we present a systematic approach to…

Biomolecules · Quantitative Biology 2024-12-18 Elana Simon , James Zou

Protein language models (pLMs) produce per-residue representations that capture evolutionary and structural information, yet their mean-pooled sequence embeddings are not explicitly trained to reflect functional, evolutionary or structural…

Machine Learning · Computer Science 2026-05-11 Dan Ofer , Oriel Perets , Michal Linial , Nadav Rappoport

Parameter-Efficient Fine-Tuning (PEFT) is widely used for adapting Large Language Models (LLMs) for various tasks. Recently, there has been an increasing demand for fine-tuning a single LLM for multiple tasks because it requires overall…

Computation and Language · Computer Science 2026-05-15 Anjir Ahmed Chowdhury , Syed Zawad , Xiaolong Ma , Xu Dong , Feng Yan

Modern Protein Language Models (PLMs) apply transformer-based model architectures from natural language processing to biological sequences, predicting a variety of protein functions and properties. However, protein language has key…

Machine Learning · Computer Science 2026-02-25 Anna Hart , Chi Han , Jeonghwan Kim , Huimin Zhao , Heng Ji

Parameter-efficient (PE) methods (like Prompts or Adapters) for adapting pre-trained language models (PLM) to downstream tasks have been popular recently. However, hindrances still prevent these methods from reaching their full potential.…

Computation and Language · Computer Science 2024-05-31 Shih-Cheng Huang , Shih-Heng Wang , Min-Han Shih , Saurav Sahay , Hung-yi Lee

Adapter Tuning, which freezes the pretrained language models (PLMs) and only fine-tunes a few extra modules, becomes an appealing efficient alternative to the full model fine-tuning. Although computationally efficient, the recent Adapters…

Computation and Language · Computer Science 2022-11-11 Shwai He , Liang Ding , Daize Dong , Miao Zhang , Dacheng Tao

Large pretrained language models (PLMs) are often domain- or task-adapted via fine-tuning or prompting. Finetuning requires modifying all of the parameters and having enough data to avoid overfitting while prompting requires no training and…

Computation and Language · Computer Science 2022-07-11 Zejiang Hou , Julian Salazar , George Polovets
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