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A new model for generating survival trajectories and data based on applying an autoencoder of a specific structure is proposed. It solves three tasks. First, it provides predictions in the form of the expected event time and the survival…

Machine Learning · Computer Science 2024-02-20 Andrei V. Konstantinov , Stanislav R. Kirpichenko , Lev V. Utkin

The field of health informatics has been profoundly influenced by the development of random forest models, which have led to significant advances in the interpretability of feature interactions. These models are characterized by their…

Machine Learning · Computer Science 2025-06-04 Akshat Dubey , Aleksandar Anžel , Georges Hattab

Machine learning algorithms often assume that training samples are independent. When data points are connected by a network, the induced dependency between samples is both a challenge, reducing effective sample size, and an opportunity to…

Machine Learning · Statistics 2025-09-22 Tiffany M. Tang , Elizaveta Levina , Ji Zhu

We propose a novel approach that integrates machine learning into compartmental disease modeling to predict the progression of COVID-19. Our model is explainable by design as it explicitly shows how different compartments evolve and it uses…

Explaining recommendations enables users to understand whether recommended items are relevant to their needs and has been shown to increase their trust in the system. More generally, if designing explainable machine learning models is key…

Machine Learning · Computer Science 2020-08-27 Darius Afchar , Romain Hennequin

Machine learning (ML) research has yielded powerful tools for training accurate prediction models despite complex multivariate associations (e.g. interactions and heterogeneity). In fields such as medicine, improved interpretability of ML…

Machine Learning · Computer Science 2021-04-28 Robert Zhang , Rachael Stolzenberg-Solomon , Shannon M. Lynch , Ryan J. Urbanowicz

The successful application of epidemic models hinges on our ability to estimate model parameters from limited observations reliably. An often-overlooked step before estimating model parameters consists of ensuring that the model parameters…

Quantitative Methods · Quantitative Biology 2023-09-29 Gerardo Chowell , Sushma Dahal , Yuganthi R. Liyanage , Amna Tariq , Necibe Tuncer

Distal myopathy represents a genetically heterogeneous group of skeletal muscle disorders with broad clinical manifestations, posing diagnostic challenges in radiology. To address this, we propose a novel multimodal attention-aware fusion…

This paper explores interpretability techniques for two of the most successful learning algorithms in medical decision-making literature: deep neural networks and random forests. We applied these algorithms in a real-world medical dataset…

Machine Learning · Computer Science 2020-02-24 Catarina Moreira , Renuka Sindhgatta , Chun Ouyang , Peter Bruza , Andreas Wichert

Symbolic regression searches for analytic expressions that accurately describe studied phenomena. The main attraction of this approach is that it returns an interpretable model that can be insightful to users. Historically, the majority of…

It is becoming increasingly important for machine learning methods to make predictions that are interpretable as well as accurate. In many practical applications, it is of interest which features and feature interactions are relevant to the…

Machine Learning · Statistics 2016-02-09 Viktoriya Krakovna , Jiong Du , Jun S. Liu

With the rise in the employment of deep learning methods in safety-critical scenarios, interpretability is more essential than ever before. Although many different directions regarding interpretability have been explored for visual…

Machine Learning · Computer Science 2020-04-08 Shoaib Ahmed Siddiqui , Dominique Mercier , Andreas Dengel , Sheraz Ahmed

Predicting high-dimensional or extreme multilabels, such as in medical coding, requires both accuracy and interpretability. Existing works often rely on local interpretability methods, failing to provide comprehensive explanations of the…

Computation and Language · Computer Science 2025-03-25 John Wu , David Wu , Jimeng Sun

Supervised learning of time series data has been extensively studied for the case of a categorical target variable. In some application domains, e.g., energy, environment and health monitoring, it occurs that the target variable is…

Machine Learning · Computer Science 2021-05-11 Dominique Gay , Alexis Bondu , Vincent Lemaire , Marc Boullé

Deep neural networks exhibit remarkable performance, yet their black-box nature limits their utility in fields like healthcare where interpretability is crucial. Existing explainability approaches often sacrifice accuracy and lack…

Machine Learning · Computer Science 2025-04-08 Linhui Huang , Sayeri Lala , Niraj K. Jha

Interpretability of a predictive model is a powerful feature that gains the trust of users in the correctness of the predictions. In word sense disambiguation (WSD), knowledge-based systems tend to be much more interpretable than…

Computation and Language · Computer Science 2018-05-21 Alexander Panchenko , Fide Marten , Eugen Ruppert , Stefano Faralli , Dmitry Ustalov , Simone Paolo Ponzetto , Chris Biemann

Interpretability research often aims to predict how a model will respond to targeted interventions on specific mechanisms. However, it rarely predicts how a model will respond to unseen input data. This paper explores the promises and…

Machine Learning · Computer Science 2025-07-10 Victoria R. Li , Jenny Kaufmann , Martin Wattenberg , David Alvarez-Melis , Naomi Saphra

Machine learning systems show significant promise for forecasting patient adverse events via risk scores. However, these risk scores implicitly encode assumptions about future interventions that the patient is likely to receive, based on…

Exponential growth in Electronic Healthcare Records (EHR) has resulted in new opportunities and urgent needs for discovery of meaningful data-driven representations and patterns of diseases in Computational Phenotyping research. Deep…

Machine Learning · Statistics 2015-12-14 Zhengping Che , Sanjay Purushotham , Robinder Khemani , Yan Liu

This work presents a new classifier that is specifically designed to be fully interpretable. This technique determines the probability of a class outcome, based directly on probability assignments measured from the training data. The…

Machine Learning · Statistics 2017-10-31 Sapan Agarwal , Corey M. Hudson