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Retinal degenerative diseases cause profound visual impairment in more than 10 million people worldwide, and retinal prostheses are being developed to restore vision to these individuals. Analogous to cochlear implants, these devices…

Computer Vision and Pattern Recognition · Computer Science 2021-02-02 Nicole Han , Sudhanshu Srivastava , Aiwen Xu , Devi Klein , Michael Beyeler

This study proposes a retinal prosthetic simulation framework driven by visual fixations, inspired by the saccade mechanism, and assesses performance improvements through end-to-end optimization in a classification task. Salient patches are…

Computer Vision and Pattern Recognition · Computer Science 2026-02-23 Yuli Wu , Do Dinh Tan Nguyen , Henning Konermann , Rüveyda Yilmaz , Peter Walter , Johannes Stegmaier

Prosthetic vision is being applied to partially recover the retinal stimulation of visually impaired people. However, the phosphenic images produced by the implants have very limited information bandwidth due to the poor resolution and lack…

Computer Vision and Pattern Recognition · Computer Science 2025-01-30 Melani Sanchez-Garcia , Ruben Martinez-Cantin , Jose J. Guerrero

Current visual implants still provide very low resolution and limited field of view, thus limiting visual acuity in implanted patients. Developments of new strategies of artificial vision simulation systems by harnessing new advancements in…

Computer Vision and Pattern Recognition · Computer Science 2022-05-24 Melani Sanchez-Garcia , Roberto Morollon-Ruiz , Ruben Martinez-Cantin , Jose J. Guerrero , Eduardo Fernandez-Jover

Visual impairments present significant challenges to individuals worldwide, impacting daily activities and quality of life. Visual neuroprosthetics offer a promising solution, leveraging advancements in technology to provide a simplified…

Human-Computer Interaction · Computer Science 2025-09-25 Eleftherios Papadopoulos , Yagmur Güçlütürk

Three critical improvements for present day and future retinal vision implants are proposed and discussed: (1) A time profile for the stimulation current that leads predominantly to transverse stimulation of nerve cells; (2) auxiliary…

Neurons and Cognition · Quantitative Biology 2012-10-22 Erich W. Schmid , Wolfgang Fink

Challenges in the field of retinal prostheses motivate the development of retinal models to accurately simulate Retinal Ganglion Cells (RGCs) responses. The goal of retinal prostheses is to enable blind individuals to solve complex,…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Nikolas Papadopoulos , Nikos Melanitis , Antonio Lozano , Cristina Soto-Sanchez , Eduardo Fernandez , Konstantina S Nikita

Implantable retinal prostheses offer a promising solution to restore partial vision by circumventing damaged photoreceptor cells in the retina and directly stimulating the remaining functional retinal cells. However, the information…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Yuli Wu , Julian Wittmann , Peter Walter , Johannes Stegmaier

Retinal prostheses restore limited visual perception, but low spatial resolution and temporal persistence make reading difficult. In sequential letter presentation, the afterimage of one symbol can interfere with perception of the next,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Jasmine Lesner , Michael Beyeler

The performance of autonomous systems heavily relies on their ability to generate a robust representation of the environment. Deep neural networks have greatly improved vision-based perception systems but still fail in challenging…

Computer Vision and Pattern Recognition · Computer Science 2018-10-16 Jörg Wagner , Volker Fischer , Michael Herman , Sven Behnke

Spatial scheduling of electrode activation ("rastering") is essential for safely operating high-density retinal implants, yet its perceptual consequences remain poorly understood. This study systematically evaluates the impact of raster…

Human-Computer Interaction · Computer Science 2025-06-25 Justin M. Kasowski , Apurv Varshney , Roksana Sadeghi , Michael Beyeler

Time series foundation models excel at diverse time series forecasting tasks, but their capacity for continuous improvement through incremental learning remains unexplored. We present the first comprehensive study investigating these…

Machine Learning · Computer Science 2025-04-22 Jia Liu , Cheng Jinguo , Xia Fang , Zhenyuan Ma , Yuankai Wu

We investigate numerically the dynamics of three different spin models in the aging regime. Each of these models is meant to be representative of a distinct class of aging behavior: coarsening systems, discontinuous spin glasses, and…

Disordered Systems and Neural Networks · Physics 2009-11-10 Andrea Montanari , Federico Ricci-Tersenghi

Understanding the time evolution of physical systems is crucial to revealing fundamental characteristics that are hidden in frequency domain. In optical science, high-quality resonance cavities and enhanced interactions with matters are at…

Optics · Physics 2021-09-22 Yingheng Tang , Jichao Fan , Xinwei Li , Jianzhu Ma , Minghao Qi , Cunxi Yu , Weilu Gao

Prognostic models aim to predict the future course of a disease or condition and are a vital component of personalized medicine. Statistical models make use of longitudinal data to capture the temporal aspect of disease progression;…

Machine Learning · Computer Science 2020-07-13 Joshua Bridge , Simon P. Harding , Yalin Zheng

Diffusion models have emerged as powerful priors for single-image restoration, but their application to zero-shot video restoration suffers from temporal inconsistencies due to the stochastic nature of sampling and complexity of…

Image and Video Processing · Electrical Eng. & Systems 2025-10-30 Nasrin Rahimi , A. Murat Tekalp

The retinal pigment epithelium (RPE) is a key site of pathogenesis for many retina diseases. The formation of drusen in the retina is characteristic of retinal degeneration. We investigate morphological changes in the RPE in the presence of…

Tissues and Organs · Quantitative Biology 2017-03-03 K. I. Mazzitello , Q. Zhang , M. A. Chrenek , F. Family , H. E. Grossniklaus , J. M. Nickerson , Y. Jiang

While deep learning surpasses human-level performance in narrow and specific vision tasks, it is fragile and over-confident in classification. For example, minor transformations in perspective, illumination, or object deformation in the…

Computer Vision and Pattern Recognition · Computer Science 2022-03-15 Maryam Daniali , Edward Kim

Predicting disease progression from longitudinal imaging is useful for clinical decision making and trial design. Recent methods have moved toward increasing generative complexity, but the conditions under which this complexity is necessary…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Liyin Chen , Nazlee Zebardast , Mengyu Wang , Tobias Elze , Jason I. Comander

Ophthalmic images may contain identical-looking pathologies that can cause failure in automated techniques to distinguish different retinal degenerative diseases. Additionally, reliance on large annotated datasets and lack of knowledge…

Image and Video Processing · Electrical Eng. & Systems 2022-08-02 Sharif Amit Kamran , Khondker Fariha Hossain , Alireza Tavakkoli , Stewart Lee Zuckerbrod , Salah A. Baker
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