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Prompt engineering has emerged as an indispensable technique for extending the capabilities of large language models (LLMs) and vision-language models (VLMs). This approach leverages task-specific instructions, known as prompts, to enhance…

Artificial Intelligence · Computer Science 2025-03-18 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Vinija Jain , Samrat Mondal , Aman Chadha

This paper explores the application of prompt engineering to enhance the performance of large language models (LLMs) in the domain of Traditional Chinese Medicine (TCM). We propose TCM-Prompt, a framework that integrates various pre-trained…

Computation and Language · Computer Science 2024-10-28 Yirui Chen , Qinyu Xiao , Jia Yi , Jing Chen , Mengyang Wang

Prompt engineering has emerged as a critical component in optimizing large language models (LLMs) for domain-specific tasks. However, the role of prompt specificity, especially in domains like STEM (physics, chemistry, biology, computer…

Computation and Language · Computer Science 2025-05-26 Dimitri Schreiter

Large Language Models (LLMs) have demonstrated remarkable success in various tasks such as natural language understanding, text summarization, and machine translation. However, their general-purpose nature often limits their effectiveness…

Computation and Language · Computer Science 2025-09-03 Zirui Song , Bin Yan , Yuhan Liu , Miao Fang , Mingzhe Li , Rui Yan , Xiuying Chen

Large Language models (LLMs) have emerged as powerful tools for addressing challenges across diverse domains. Notably, recent studies have demonstrated that large language models significantly enhance the efficiency of biomolecular analysis…

Computation and Language · Computer Science 2025-03-07 Jiyue Jiang , Zikang Wang , Yuheng Shan , Heyan Chai , Jiayi Li , Zixian Ma , Xinrui Zhang , Yu Li

Large language models (LLMs) have shown remarkable performance on many different Natural Language Processing (NLP) tasks. Prompt engineering plays a key role in adding more to the already existing abilities of LLMs to achieve significant…

Computation and Language · Computer Science 2024-07-25 Shubham Vatsal , Harsh Dubey

Multimodal Large Language Models (MLLMs) are set to transform how machines process and generate human-like responses by integrating diverse modalities such as text, images, and code. Yet, effectively harnessing their capabilities hinges on…

Artificial Intelligence · Computer Science 2025-04-15 Anwesha Mohanty , Venkatesh Balavadhani Parthasarathy , Arsalan Shahid

This comprehensive review delves into the pivotal role of prompt engineering in unleashing the capabilities of Large Language Models (LLMs). The development of Artificial Intelligence (AI), from its inception in the 1950s to the emergence…

Computation and Language · Computer Science 2025-06-18 Banghao Chen , Zhaofeng Zhang , Nicolas Langrené , Shengxin Zhu

Large language models (LLMs) have demonstrated rapid progress across a wide array of domains. Owing to the very large number of parameters and training data in LLMs, these models inherently encompass an expansive and comprehensive materials…

Materials Science · Physics 2024-11-20 Siyu Liu , Tongqi Wen , A. S. L. Subrahmanyam Pattamatta , David J. Srolovitz

Large language models (LLMs) have shown remarkable capabilities in Natural Language Processing (NLP), especially in domains where labeled data is scarce or expensive, such as clinical domain. However, to unlock the clinical knowledge hidden…

Computation and Language · Computer Science 2023-09-18 Sonish Sivarajkumar , Mark Kelley , Alyssa Samolyk-Mazzanti , Shyam Visweswaran , Yanshan Wang

This work presents an ontology-integrated large language model (LLM) framework for chemical engineering that unites structured domain knowledge with generative reasoning. The proposed pipeline aligns model training and inference with the…

Machine Learning · Computer Science 2025-12-15 Crystal Su , Kuai Yu , Jingrui Zhang , Mingyuan Shao , Daniel Bauer

The introduction of large language models (LLMs) has enhanced automation in software engineering tasks, including in Model Driven Engineering (MDE). However, using general-purpose LLMs for domain modeling has its limitations. One approach…

Software Engineering · Computer Science 2025-07-22 Vladyslav Bulhakov , Giordano d'Aloisio , Claudio Di Sipio , Antinisca Di Marco , Davide Di Ruscio

The rise of large language models (LLMs) has highlighted the importance of prompt engineering as a crucial technique for optimizing model outputs. While experimentation with various prompting methods, such as Few-shot, Chain-of-Thought, and…

Artificial Intelligence · Computer Science 2026-03-27 Michael Hewing , Vincent Leinhos

While Large Language Models (LLMs) are being quickly adapted to many domains, including healthcare, their strengths and pitfalls remain under-explored. In our study, we examine the effects of prompt engineering to guide Large Language…

Computation and Language · Computer Science 2024-09-04 Daniil Filienko , Yinzhou Wang , Caroline El Jazmi , Serena Xie , Trevor Cohen , Martine De Cock , Weichao Yuwen

Predicting molecular properties is a critical component of drug discovery. Recent advances in deep learning, particularly Graph Neural Networks (GNNs), have enabled end-to-end learning from molecular structures, reducing reliance on manual…

Computation and Language · Computer Science 2025-09-26 Peng Zhou , Lai Hou Tim , Zhixiang Cheng , Kun Xie , Chaoyi Li , Wei Liu , Xiangxiang Zeng

Prompt engineering is an increasingly important skill set needed to converse effectively with large language models (LLMs), such as ChatGPT. Prompts are instructions given to an LLM to enforce rules, automate processes, and ensure specific…

Prompt engineering is crucial for harnessing the potential of large language models (LLMs), especially in the medical domain where specialized terminology and phrasing is used. However, the efficacy of prompt engineering in the medical…

Computation and Language · Computer Science 2025-07-22 Jamil Zaghir , Marco Naguib , Mina Bjelogrlic , Aurélie Névéol , Xavier Tannier , Christian Lovis

Process discovery aims to derive process models from event logs, providing insights into operational behavior and forming a foundation for conformance checking and process improvement. However, models derived solely from event data may not…

Artificial Intelligence · Computer Science 2025-10-09 Ali Norouzifar , Humam Kourani , Marcus Dees , Wil van der Aalst

Prompt engineering has rapidly emerged as a critical skill for effective interaction with large language models (LLMs). However, the cognitive and neural underpinnings of this expertise remain largely unexplored. This paper presents…

The rapid emergence of generative AI models like Large Language Models (LLMs) has demonstrated its utility across various activities, including within Requirements Engineering (RE). Ensuring the quality and accuracy of LLM-generated output…

Software Engineering · Computer Science 2025-07-08 Krishna Ronanki , Simon Arvidsson , Johan Axell
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