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Fault-tolerant protocols enable large and precise quantum algorithms. Many such protocols rely on a feed-forward processing of data, enabled by a hybrid of quantum and classical logic. Representing the control structure of such programs can…

Quantum computing is performed on Noisy Intermediate-Scale Quantum (NISQ) hardware in the short term. Only small circuits can be executed reliably on a quantum machine due to the unavoidable noisy quantum operations on NISQ devices, leading…

Hardware Architecture · Computer Science 2021-12-02 Siyuan Niu , Aida Todri-Sanial

Quantum machine learning (QML) has emerged as an innovative framework with the potential to uncover complex patterns by leveraging quantum systems ability to simulate and exploit high-dimensional latent spaces, particularly in learning…

Quantum Physics · Physics 2025-04-08 Ziqing Guo , Alex Khan , Victor S. Sheng , Shabnam Jabeen , Ziwen Pan

High-Performance Computing (HPC) systems are the most powerful tools that we currently have to solve complex scientific simulations. Quantum computing (QC) has the potential to enhance HPC systems by accelerating the execution of specific…

We define some of the programming and system-level challenges facing the application of quantum processing to high-performance computing. Alongside barriers to physical integration, prominent differences in the execution of quantum and…

Quantum Physics · Physics 2017-12-06 Keith A. Britt , Fahd A. Mohiyaddin , Travis S. Humble

Quantum circuit execution is the central task in quantum computation. Due to inherent quantum-mechanical constraints, quantum computing workflows often involve a considerable number of independent measurements over a large set of slightly…

Quantum Physics · Physics 2024-06-06 Daniel Claudino , Dmitry I. Lyakh , Alexander J. McCaskey

We introduce isQ, a new software stack for quantum programming in an imperative programming language, also named isQ. The aim of isQ is to make the programmers write quantum programs as conveniently as possible. In particular: 1) The isQ…

Quantum Physics · Physics 2023-11-22 Jingzhe Guo , Huazhe Lou , Riling Li , Wang Fang , Junyi Liu , Peixun Long , Shenggang Ying , Mingsheng Ying

As customized accelerator design has become increasingly popular to keep up with the demand for high performance computing, it poses challenges for modern simulator design to adapt to such a large variety of accelerators. Existing…

Programming Languages · Computer Science 2022-02-03 Zhijing Li , Yuwei Ye , Stephen Neuendorffer , Adrian Sampso

Hybrid quantum-high performance computing (Q-HPC) workflows are emerging as a key strategy for running quantum applications at scale in current noisy intermediate-scale quantum (NISQ) devices. These workflows must operate seamlessly across…

We present qcor - a language extension to C++ and compiler implementation that enables heterogeneous quantum-classical programming, compilation, and execution in a single-source context. Our work provides a first-of-its-kind C++ compiler…

With the potential of quantum algorithms to solve intractable classical problems, quantum computing is rapidly evolving and more algorithms are being developed and optimized. Expressing these quantum algorithms using a high-level language…

Quantum Physics · Physics 2020-05-28 N. Khammassi , I. Ashraf , J. v. Someren , R. Nane , A. M. Krol , M. A. Rol , L. Lao , K. Bertels , C. G. Almudever

NISQ devices have several physical limitations and unavoidable noisy quantum operations, and only small circuits can be executed on a quantum machine to get reliable results. This leads to the quantum hardware under-utilization issue. Here,…

Hardware Architecture · Computer Science 2023-02-22 Siyuan Niu , Aida Todri-Sanial

To address the growing needs for scalable High Performance Computing (HPC) and Quantum Computing (QC) integration, we present our HPC-QC full stack framework and its hybrid workload development capability with modular…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-24 Xin Zhan , K. Grace Johnson , Aniello Esposito , Barbara Chapman , Marco Fiorentino , Kirk M. Bresniker , Raymond G. Beausoleil , Masoud Mohseni

Quantum computers are available via a variety of different quantum cloud offerings. These offerings are heterogeneous and differ in features, such as pricing models or types of access to quantum computers. Furthermore, quantum circuits can…

As more applications utilize virtualization and emulation to run mission-critical tasks, the performance requirements of emulated and virtualized platforms continue to rise. Hardware virtualization is not universally available for all…

Performance · Computer Science 2025-01-08 Amy Iris Parker

We present the Quantum Virtual Machine (QVM), an end-to-end generic system for scalable execution of large quantum circuits with high fidelity on noisy and small quantum processors (QPUs) by leveraging gate virtualization. QVM exposes a…

Quantum Physics · Physics 2024-07-01 Nathaniel Tornow , Emmanouil Giortamis , Pramod Bhatotia

Embedded quantum machine learning (EQML) seeks to bring quantum machine learning (QML) capabilities to resource-constrained edge platforms such as IoT nodes, wearables, drones, and cyber-physical controllers. In 2026, EQML is technically…

Machine Learning · Computer Science 2026-03-16 Somdip Dey , Syed Muhammad Raza

We present a composable design scheme for the development of hybrid quantum/classical algorithms and workflows for applications of quantum simulation. Our object-oriented approach is based on constructing an expressive set of common data…

We present sqire, a low-level language for quantum computing and verification. sqire uses a global register of quantum bits, allowing easy compilation to and from existing `quantum assembly' languages and simplifying the verification…

Logic in Computer Science · Computer Science 2019-12-09 Kesha Hietala , Robert Rand , Shih-Han Hung , Xiaodi Wu , Michael Hicks

This paper introduces a vision for Quantum Software Development lifecycle, proposing a hybrid full-stack iterative model that integrates quantum and classical computing. Addressing the current challenges in Quantum Computing (QC) such as…

Software Engineering · Computer Science 2025-04-09 Arif Ali Khan , Davide Taibi , Muhammad Azeem Akbar