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We propose a modified expectation-maximization algorithm by introducing the concept of quantum annealing, which we call the deterministic quantum annealing expectation-maximization (DQAEM) algorithm. The expectation-maximization (EM)…

Machine Learning · Statistics 2017-01-13 Hideyuki Miyahara , Koji Tsumura , Yuki Sughiyama

Quantum computing is a computational paradigm with the potential to outperform classical methods for a variety of problems. Proposed recently, the Quantum Approximate Optimization Algorithm (QAOA) is considered as one of the leading…

Machine Learning · Computer Science 2022-06-16 Sami Khairy , Ruslan Shaydulin , Lukasz Cincio , Yuri Alexeev , Prasanna Balaprakash

The recent advent of commercially available quantum annealing hardware (QAH) has expanded opportunities for research into quantum annealing-based algorithms. In the domain of power systems, this advancement has driven increased interest in…

Optimization and Control · Mathematics 2025-03-26 Rosemary Barrass , Harsha Nagarajan , Carleton Coffrin

Molecular docking plays a pivotal role in drug discovery and precision medicine, enabling us to understand protein functions and advance novel therapeutics. Here, we introduce a potential alternative solution to this problem, the…

Quantum Physics · Physics 2024-05-17 Qi-Ming Ding , Yi-Ming Huang , Xiao Yuan

Quantum annealers provide an effective framework for solving large-scale combinatorial optimization problems. This work presents a novel methodology for training Variational Quantum Algorithms (VQAs) by reformulating the parameter…

Quantum Physics · Physics 2025-09-03 Ernesto Acosta , Guillermo Botella , Carlos Cano

We present Quafu-Qcover, an open-source cloud-based software package designed for combinatorial optimization problems that support both quantum simulators and hardware backends. Quafu-Qcover provides a standardized and complete workflow for…

Quantum Physics · Physics 2023-05-30 BAQIS Quafu Group

The Quantum Approximate Optimization Algorithm (QAOA) by Farhi et al. is a quantum computational framework for solving quantum or classical optimization tasks. Here, we explore using QAOA for Binary Linear Least Squares (BLLS); a problem…

Quantum Physics · Physics 2021-04-27 Ajinkya Borle , Vincent E. Elfving , Samuel J. Lomonaco

Quantum computers are expected to offer significant advantages in solving complex optimization problems that are challenging for classical computers. Quadratic Unconstrained Binary Optimization (QUBO) problems represent an important class…

Quantum Physics · Physics 2025-10-15 Teemu Pihkakoski , Aravind Plathanam Babu , Pauli Taipale , Petri Liimatta , Matti Silveri

An important task in multi-objective optimization is generating the Pareto front -- the set of all Pareto-optimal compromises among multiple objective functions applied to the same set of variables. Since this task can be computationally…

Quantum Physics · Physics 2025-11-04 Andrew D. King

We present a comparison between the Quantum Approximate Optimization Algorithm (QAOA) and two widely studied competing methods, Quantum Annealing (QA) and Simulated Annealing (SA). To achieve this, we define a class of optimization problems…

Quantum Physics · Physics 2019-01-08 Michael Streif , Martin Leib

Quantum annealing (QA) is a hardware-based heuristic optimization and sampling method applicable to discrete undirected graphical models. While similar to simulated annealing, QA relies on quantum, rather than thermal, effects to explore…

Quantum Annealing (QA) uses quantum fluctuations to search for a global minimum of an optimization-type problem faster than classical computers. To meet the demand for future internet traffic and mitigate the spectrum scarcity, this work…

Information Theory · Computer Science 2023-01-11 Eldar Gabdulsattarov , Khaled Rabie , Xingwang Li , Galymzhan Nauryzbayev

The Quantum Approximate Optimization Algorithm (QAOA) is a hybrid quantum-classical variational algorithm designed to tackle combinatorial optimization problems. Despite its promise for near-term quantum applications, not much is currently…

Quantum Physics · Physics 2020-06-26 Leo Zhou , Sheng-Tao Wang , Soonwon Choi , Hannes Pichler , Mikhail D. Lukin

Quantum annealing (QA) has attracted research interest as a sampler and combinatorial optimization problem (COP) solver. A recently proposed sampling-based solver for QA significantly reduces the required number of qubits, being capable of…

Quantum Physics · Physics 2025-07-31 Ryo Hagiwara , Shunta Arai , Satoshi Takabe

Optimization problems are ubiquitous in various industrial settings, and multi-knapsack optimization is one recurrent task faced daily by several industries. The advent of quantum computing has opened a new paradigm for computationally…

Practical applications of quantum computing depend on fault-tolerant devices with error correction. Today, the most promising approach is a class of error-correcting codes called surface codes. We study the problem of compiling quantum…

Quantum Physics · Physics 2025-04-29 Abtin Molavi , Amanda Xu , Swamit Tannu , Aws Albarghouthi

We introduce the reinforcement quantum annealing (RQA) scheme in which an intelligent agent interacts with a quantum annealer that plays the stochastic environment role of learning automata and tries to iteratively find better Ising…

Quantum Physics · Physics 2020-01-03 Ramin Ayanzadeh , Milton Halem , Tim Finin

Constrained combinatorial optimization with strict linear constraints underpins applications in drug discovery, power grids, logistics, and finance, yet remains computationally demanding for classical algorithms, especially at large scales.…

Quantum Physics · Physics 2026-04-07 Yajie Hao , Qiming Ding , Xiao Yuan , Xiaoting Wang

Quantum-classical hybrid algorithms offer a promising strategy for tackling computationally challenging problems, such as the maximum independent set (MIS) problem that plays a crucial role in areas like network design and data analysis.…

Quantum Physics · Physics 2025-06-17 Seokho Jeong , Juyoung Park , Jaewook Ahn

High-energy physics is replete with hard computational problems and it is one of the areas where quantum computing could be used to speed up calculations. We present an implementation of likelihood-based regularized unfolding on a quantum…

Data Analysis, Statistics and Probability · Physics 2020-10-09 Kyle Cormier , Riccardo Di Sipio , Peter Wittek
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