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Stochastic systems in biology often exhibit substantial variability within and between cells. This variability, as well as having dramatic functional consequences, provides information about the underlying details of the system's behaviour.…

Quantitative Methods · Quantitative Biology 2015-11-09 Iain G. Johnston

The cellular automaton is a widely known model of both reversible and irreversible computations. The family of reversible second-order cellular automata considered in this work is appropriate both for construction of logic gates and…

Cellular Automata and Lattice Gases · Physics 2024-05-10 Alexander Yu. Vlasov

Stochastic dynamical systems arise naturally across nearly all areas of science and engineering. Typically, a dynamical system model is based on some prior knowledge about the underlying dynamics of interest in which probabilistic features…

Computational Engineering, Finance, and Science · Computer Science 2021-09-03 Chao Yin , Xihaier Luo , Ahsan Kareem

The theory of cellular automata in operational probabilistic theories is developed. We start introducing the composition of infinitely many elementary systems, and then use this notion to define update rules for such infinite composite…

Quantum Physics · Physics 2021-07-09 Paolo Perinotti

We explore probability modelling of discretization uncertainty for system states defined implicitly by ordinary or partial differential equations. Accounting for this uncertainty can avoid posterior under-coverage when likelihoods are…

Methodology · Statistics 2016-10-25 Oksana A. Chkrebtii , David A. Campbell , Ben Calderhead , Mark A. Girolami

We study the predictability of emergent phenomena in complex systems. Using nearest neighbor, one-dimensional Cellular Automata (CA) as an example, we show how to construct local coarse-grained descriptions of CA in all classes of Wolfram's…

Cellular Automata and Lattice Gases · Physics 2015-06-26 Navot Israeli , Nigel Goldenfeld

A general mathematical method is presented for the systematic construction of coupled map lattices (CMLs) out of deterministic cellular automata (CAs). The entire CA rule space is addressed by means of a universal map for CAs that we have…

Cellular Automata and Lattice Gases · Physics 2016-06-09 Vladimir García-Morales

Deep learning techniques have recently demonstrated broad success in predicting complex dynamical systems ranging from turbulence to human speech, motivating broader questions about how neural networks encode and represent dynamical rules.…

Cellular Automata and Lattice Gases · Physics 2020-01-20 William Gilpin

We extend Cellular Automata to time-varying discrete geometries. In other words we formalize, and prove theorems about, the intuitive idea of a discrete manifold which evolves in time, subject to two natural constraints: the evolution does…

Discrete Mathematics · Computer Science 2018-07-17 Pablo Arrighi , Clément Chouteau , Stefano Facchini , Simon Martiel

Continuum models for the spatial dynamics of growing cell populations have been widely used to investigate the mechanisms underpinning tissue development and tumour invasion. These models consist of nonlinear partial differential equations…

Tissues and Organs · Quantitative Biology 2019-07-15 Mark AJ Chaplain , Tommaso Lorenzi , Fiona R Macfarlane

We consider random boolean cellular automata on the integer lattice, i.e., the cells are identified with the integers from 1 to $N$. The behaviour of the automaton is mainly determined by the support of the random variable that selects one…

Probability · Mathematics 2011-01-07 F. M. Dekking , L. van Driel , A. Fey

We study distributed principal component analysis (PCA) in high-dimensional settings under the spiked model. In such regimes, sample eigenvectors can deviate significantly from population ones, introducing a persistent bias. Existing…

Methodology · Statistics 2025-05-29 Weiming Li , Zeng Li , Siyu Wang , Yanqing Yin , Junpeng Zhu

We consider transformations between attractor basins of binary cylindrical cellular automata resulting from mutations. A t-point mutation of a state consists in toggling t sites in that state. Results of such mutations are described by a…

Cellular Automata and Lattice Gases · Physics 2007-05-23 Burton Voorhees , Catherine Beauchemin

Lyophilization, aka freeze drying, is a process commonly used to increase the stability of various drug products in biotherapeutics manufacturing, e.g., mRNA vaccines, allowing for higher storage temperature. While the current trends in the…

Computational Engineering, Finance, and Science · Computer Science 2025-02-20 Prakitr Srisuma , George Barbastathis , Richard D. Braatz

Cellular automata (CA) are fully discrete alternatives to partial differential equations (PDE). For PDEs, one often considers the Cauchy problem, or initial value problem: find the solution of the PDE satisfying a given initial condition.…

Cellular Automata and Lattice Gases · Physics 2020-02-24 Henryk Fukś

Probabilistic deterministic finite automata (PDFA) are discrete event systems modeling conditional probabilities over languages: Given an already seen sequence of tokens they return the probability of tokens of interest to appear next.…

Formal Languages and Automata Theory · Computer Science 2024-07-01 Robert Baumgartner , Sicco Verwer

Recent evidence suggests that nongenetic (epigenetic) mechanisms play an important role at all stages of cancer evolution. In many cancers, these mechanisms have been observed to induce dynamic switching between two or more cell states,…

Quantitative Methods · Quantitative Biology 2023-06-16 Einar Bjarki Gunnarsson , Jasmine Foo , Kevin Leder

In this paper, we study the probabilistic stability analysis of a subclass of stochastic hybrid systems, called the Planar Probabilistic Piecewise Constant Derivative Systems (Planar PPCD), where the continuous dynamics is deterministic,…

Robotics · Computer Science 2022-09-07 Spandan Das , Pavithra Prabhakar

Mathematical models are vital interpretive and predictive tools used to assist in the understanding of cell migration. There are typically two approaches to modelling cell migration: either micro-scale, discrete or macro-scale, continuum.…

Cell Behavior · Quantitative Biology 2018-08-16 Enrico Gavagnin , Christian A. Yates

A classical approach to formal policy synthesis in stochastic dynamical systems is to construct a finite-state abstraction, often represented as a Markov decision process (MDP). The correctness of these approaches hinges on a behavioural…

Systems and Control · Electrical Eng. & Systems 2025-08-08 Thom Badings , Alessandro Abate
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