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This paper introduces MAD-MIL, a Multi-head Attention-based Deep Multiple Instance Learning model, designed for weakly supervised Whole Slide Images (WSIs) classification in digital pathology. Inspired by the multi-head attention mechanism…

Weak supervision learning on classification labels has demonstrated high performance in various tasks, while a few pixel-level fine annotations are also affordable. Naturally a question comes to us that whether the combination of…

Multimodal medical image fusion integrates complementary information from different imaging modalities to enhance diagnostic accuracy and treatment planning. While deep learning methods have advanced performance, existing approaches face…

Recent advancements in State Space Models, notably Mamba, have demonstrated superior performance over the dominant Transformer models, particularly in reducing the computational complexity from quadratic to linear. Yet, difficulties in…

State Space Models (SSMs), especially Mamba, have shown great promise in medical image segmentation due to their ability to model long-range dependencies with linear computational complexity. However, accurate medical image segmentation…

We present an approach to efficiently and effectively adapt a masked image modeling (MIM) pre-trained vanilla Vision Transformer (ViT) for object detection, which is based on our two novel observations: (i) A MIM pre-trained vanilla ViT…

Medicine is inherently a multimodal discipline. Medical images can reflect the pathological changes of cancer and tumors, while the expression of specific genes can influence their morphological characteristics. However, most deep learning…

Deep learning has shown strong potential in cancer classification from whole-slide images (WSIs), but the need for extensive expert annotations often limits its success. Annotation-free approaches, such as multiple instance learning (MIL)…

Medical image segmentation plays an important role in computer-aided diagnosis. Traditional convolution-based U-shape segmentation architectures are usually limited by the local receptive field. Existing vision transformers have been widely…

Multiple instance learning (MIL) has emerged as a powerful framework for weakly supervised whole slide image (WSI) classification, enabling slide-level predictions without requiring detailed patch-level annotations. Despite its success, a…

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Compared to single view medical image classification, using multiple views can significantly enhance predictive accuracy as it can account for the complementarity of each view while leveraging correlations between views. Existing multi-view…

The significant molecular and pathological heterogeneity of glioblastoma, an aggressive brain tumor, complicates diagnosis and patient stratification. While traditional histopathological assessment remains the standard, deep learning offers…

Hyperspectral Imaging (HSI) has proven to be a powerful tool for capturing detailed spectral and spatial information across diverse applications. Despite the advancements in Deep Learning (DL) and Transformer architectures for HSI…

Self-supervised learning (SSL) has been successful in building patch embeddings of small histology images (e.g., 224x224 pixels), but scaling these models to learn slide embeddings from the entirety of giga-pixel whole-slide images (WSIs)…

Classifying 3D MRI images for early detection of Alzheimer's disease is a critical task in medical imaging. Traditional approaches using Convolutional Neural Networks (CNNs) and Transformers face significant challenges in this domain. CNNs,…

In digital pathology, whole-slide images (WSIs) are often difficult to handle due to their gigapixel scale, so most approaches train patch encoders via self-supervised learning (SSL) and then aggregate the patch-level embeddings via…

Deep learning has been effective for histology image analysis in digital pathology. However, many current deep learning approaches require large, strongly- or weakly-labeled images and regions of interest, which can be time-consuming and…

Digital pathology involves converting physical tissue slides into high-resolution Whole Slide Images (WSIs), which pathologists analyze for disease-affected tissues. However, large histology slides with numerous microscopic fields pose…

Semantic segmentation of remote sensing imagery is a fundamental task in computer vision, supporting a wide range of applications such as land use classification, urban planning, and environmental monitoring. However, this task is often…