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Hyperspectral image (HSI) classification presents inherent challenges due to high spectral dimensionality, significant domain shifts, and limited availability of labeled data. To address these issues, we propose a novel Active Transfer…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Muhammad Ahmad , Francesco Mauro , Manuel Mazzara , Salvatore Distefano , Adil Mehmood Khan , Silvia Liberata Ullo

Understanding how cellular morphology, gene expression, and spatial context jointly shape tissue function is a central challenge in biology. Image-based spatial transcriptomics technologies now provide high-resolution measurements of cell…

Quantitative Methods · Quantitative Biology 2026-02-17 Zhenglun Kong , Mufan Qiu , John Boesen , Xiang Lin , Sukwon Yun , Tianlong Chen , Manolis Kellis , Marinka Zitnik

Spatial transcriptomics (ST) technologies enable gene expression profiling with spatial resolution, offering unprecedented insights into tissue organization and disease heterogeneity. However, current analysis methods often struggle with…

Recent advancements in spatial transcriptomics technologies allow researchers to simultaneously measure RNA expression levels for hundreds to thousands of genes while preserving spatial information within tissues, providing critical…

Methodology · Statistics 2025-07-31 Catherine Higgins , Jingyi Jessica Li , Michelle Carey

Diffusion-based image translation guided by semantic texts or a single target image has enabled flexible style transfer which is not limited to the specific domains. Unfortunately, due to the stochastic nature of diffusion models, it is…

Computer Vision and Pattern Recognition · Computer Science 2023-02-02 Gihyun Kwon , Jong Chul Ye

Diffusion models with continuous stochastic differential equations (SDEs) have shown superior performances in image generation. It can serve as a deep generative prior to solving the inverse problem in magnetic resonance (MR)…

Image and Video Processing · Electrical Eng. & Systems 2024-01-23 Chentao Cao , Zhuo-Xu Cui , Yue Wang , Shaonan Liu , Taijin Chen , Hairong Zheng , Dong Liang , Yanjie Zhu

Non-contrast CT (NCCT) imaging may reduce image contrast and anatomical visibility, potentially increasing diagnostic uncertainty. In contrast, contrast-enhanced CT (CECT) facilitates the observation of regions of interest (ROI). Leading…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Tingyi Lin , Pengju Lyu , Jie Zhang , Yuqing Wang , Cheng Wang , Jianjun Zhu

Spatial transcriptomics data analysis integrates cellular transcriptional activity with spatial coordinates to identify spatial domains, infer cell-type dynamics, and characterize gene expression patterns within tissues. Despite recent…

Quantitative Methods · Quantitative Biology 2026-03-25 Sean Cottrell , Guo-Wei Wei , Longxiu Huang

Spatial transcriptomic (ST) clustering employs spatial and transcription information to group spots spatially coherent and transcriptionally similar together into the same spatial domain. Graph convolution network (GCN) and graph attention…

Quantitative Methods · Quantitative Biology 2023-10-24 Chen Zhang , Junhui Gao , Lingxin Kong , Guangshuo cao , Xiangyu Guo , Wei Liu

Multimodal pathology-genomic analysis has become increasingly prominent in cancer survival prediction. However, existing studies mainly utilize multi-instance learning to aggregate patch-level features, neglecting the information loss of…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Mingcheng Qu , Guang Yang , Donglin Di , Tonghua Su , Yue Gao , Yang Song , Lei Fan

Performing super-resolution of a depth image using the guidance from an RGB image is a problem that concerns several fields, such as robotics, medical imaging, and remote sensing. While deep learning methods have achieved good results in…

Computer Vision and Pattern Recognition · Computer Science 2023-03-29 Nando Metzger , Rodrigo Caye Daudt , Konrad Schindler

Score-based diffusion modeling is a generative machine learning algorithm that can be used to sample from complex distributions. They achieve this by learning a score function, i.e., the gradient of the log-probability density of the data,…

Machine Learning · Computer Science 2025-12-17 Dibyajyoti Chakraborty , Haiwen Guan , Jason Stock , Troy Arcomano , Guido Cervone , Romit Maulik

Artistic image stylization aims to render the content provided by text or image with the target style, where content and style decoupling is the key to achieve satisfactory results. However, current methods for content and style…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Ma Zhuoqi , Zhang Yixuan , You Zejun , Tian Long , Liu Xiyang

Diffusion models, such as Stable Diffusion, have shown incredible performance on text-to-image generation. Since text-to-image generation often requires models to generate visual concepts with fine-grained details and attributes specified…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Xuehai He , Weixi Feng , Tsu-Jui Fu , Varun Jampani , Arjun Akula , Pradyumna Narayana , Sugato Basu , William Yang Wang , Xin Eric Wang

Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

Diffusion model-based approaches recently achieved re-markable success in MRI reconstruction, but integration into clinical routine remains challenging due to its time-consuming convergence. This phenomenon is partic-ularly notable when…

Image and Video Processing · Electrical Eng. & Systems 2024-11-07 Yu Guan , Qinrong Cai , Wei Li , Qiuyun Fan , Dong Liang , Qiegen Liu

Diffusion models have been used extensively for high quality image and video generation tasks. In this paper, we propose a novel conditional diffusion model with spatial attention and latent embedding (cDAL) for medical image segmentation.…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Behzad Hejrati , Soumyanil Banerjee , Carri Glide-Hurst , Ming Dong

Spatio-temporal processes often exhibit highly heterogeneous and non-intuitive responses to localized disruptions, limiting the effectiveness of conventional message passing approaches in modeling local heterogeneity. We reformulate…

Machine Learning · Computer Science 2026-04-21 Abeer Mostafa , Raneen Younis , Zahra Ahmadi

Advances in spatially-resolved transcriptomics (SRT) technologies have propelled the development of new computational analysis methods to unlock biological insights. As the cost of generating these data decreases, these technologies provide…

Genomics · Quantitative Biology 2024-08-02 Boyi Guo , Wodan Ling , Sang Ho Kwon , Pratibha Panwar , Shila Ghazanfar , Keri Martinowich , Stephanie C. Hicks

Consistency models have emerged as a promising alternative to diffusion models, offering high-quality generative capabilities through single-step sample generation. However, their application to multi-domain image translation tasks, such as…

Computer Vision and Pattern Recognition · Computer Science 2025-01-06 Amil Bhagat , Milind Jain , A. V. Subramanyam