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To explain the appearance of heterogeneities in the plasma membrane, I propose a hypothesis which begins with the observation that fluctuations in the membrane curvature are coupled to the difference between compositions in one leaf and the…

Soft Condensed Matter · Physics 2017-08-23 M. Schick

We construct a coarse-grained effective two-dimensional (2d) hydrodynamic theory as a theoretical model for a coupled system of a fluid membrane and a thin layer of a polar active fluid in its ordered state that is anchored to the membrane.…

Soft Condensed Matter · Physics 2012-11-15 Niladri Sarkar , Abhik Basu

Cell membranes are anchored to the cytoskeleton via immobile inclusions. We investigate the effect of such anchors on the in-plane dynamics of a fluid membrane and mobile inclusions (proteins) embedded in it. The immobile particles lead to…

Soft Condensed Matter · Physics 2012-02-02 Naomi Oppenheimer , Haim Diamant

Using numerical simulations, we characterized the behavior of an elastic membrane immersed in an active fluid. Our findings reveal a nontrivial folding and re-expansion of the membrane that is controlled by the interplay of its resistance…

Soft Condensed Matter · Physics 2015-07-24 S. A. Mallory , C. Valeriani , A. Cacciuto

We study, using dissipative particle dynamics simulations, the effect of active lipid flip-flop on model fluid bilayer membranes. We consider both cases of symmetric as well as asymmetric flip-flops. Symmetric flip-flop leads to a steady…

Soft Condensed Matter · Physics 2009-11-13 Sanoop Ramachandran , P. B. Sunil Kumar , Mohamed Laradji

Diffusion rates through a membrane can be asymmetric, if the diffusing particles are spatially extended and the pores in the membrane have asymmetric structure. This phenomenon is demonstrated here via a deterministic simulation of a…

Statistical Mechanics · Physics 2007-05-23 Norman Packard , Rob Shaw

The transport of individual entities through interconnected structures is a process of practical relevance both in biology and technology. Examples are given by diffusive dynamics of molecules in porous structures. In soft environments,…

Soft Condensed Matter · Physics 2026-02-09 Jakob Mihatsch , Andreas M. Menzel

Thermal fluctuations strongly modify the large length-scale elastic behavior of crosslinked membranes, giving rise to scale-dependent elastic moduli. While thermal effects in flat membranes are well understood, many natural and artificial…

Soft Condensed Matter · Physics 2013-02-19 Jayson Paulose , Gerard A. Vliegenthart , Gerhard Gompper , David R. Nelson

Cellular membranes are elastic lipid bilayers that contain a variety of proteins, including ion channels, receptors, and scaffolding proteins. These proteins are known to diffuse in the plane of the membrane and to influence the bending of…

Soft Condensed Matter · Physics 2020-10-28 Arijit Mahapatra , David Saintillan , Padmini Rangamani

Using a continuum bead-spring Monte Carlo model, we study the anomalous diffusion dynamics of a self-avoiding tethered membrane by means of extensive computer simulations. We focus on the subdiffusive stochastic motion of the membrane's…

Soft Condensed Matter · Physics 2008-05-14 Hristina Popova , Andrey Milchev

The elastic properties of two-component bilayer membranes are studied using a coarse grain model for amphiphilic molecules. The two species of amphiphiles considered here differ only in their length. Molecular Dynamics simulations are…

Soft Condensed Matter · Physics 2007-05-23 Alberto Imparato , Julian C. Shillcock , Reinhard Lipowsky

We set up the statistical mechanics for a nearly flat, thermally equilibrated fluid membrane, attached to an elastic network through one of its sides. We predict that the resulting structural (inversion) asymmetry of the membrane, notably…

Soft Condensed Matter · Physics 2016-10-07 Tirthankar Banerjee , Niladri Sarkar , Abhik Basu

Biological membranes mainly consist of lipids and proteins. While the proteins have many functions as single molecules, the membrane as a whole displays physical properties that cannot be explained on the single molecule level. For example,…

Biological Physics · Physics 2009-06-09 Thomas Heimburg

We investigate the lateral dynamics in a purely viscous lipid membrane surrounded by viscoelastic media such as polymeric solutions. We first obtain the generalized frequency-dependent mobility tensor and focus on the case when the solvent…

Soft Condensed Matter · Physics 2015-06-04 S. Komura , S. Ramachandran , K. Seki

We investigate how an externally imposed curvature influences lipid segregation on two-phase-coexistent membranes. We show that the bending-modulus contrast of the two phases and the curvature act together to yield a reduced effective line…

Soft Condensed Matter · Physics 2018-06-21 Fangfu Ye , Robin L. B. Selinger , Jonathan V. Selinger

We explore how thermal fluctuations affect the mechanics of thin amorphous spherical shells. In flat membranes with a shear modulus, thermal fluctuations increase the bending rigidity and reduce the in-plane elastic moduli in a…

Soft Condensed Matter · Physics 2017-01-18 Andrej Kosmrlj , David R. Nelson

Thermal fluctuations are important for amphiphilic bilayer membranes since typical bending stiffnesses can be a few $k_B T$. The rod-like constituent molecules are generically tilted with respect to the local normal for packing reasons. We…

Condensed Matter · Physics 2009-10-28 Thomas Powers , Philip Nelson

The dynamical response of a lipid membrane to a local perturbation of its molecular symmetry is investigated theoretically. A density asymmetry between the two membrane leaflets is predominantly released by in-plane lipid diffusion or…

Soft Condensed Matter · Physics 2009-11-10 Pierre Sens

One of the most widely used methods for determination of the bending elasticity modulus of model lipid membranes is the analysis of the shape fluctuations of nearly spherical lipid vesicles. The theoretical basis of this analysis is given…

Soft Condensed Matter · Physics 2019-09-04 Isak Bivas , Nicholay S. Tonchev

We introduce and study the behavior of a tethered membrane of non-zero thickness embedded in three dimensions subject to an effective self-attraction induced by hydrophobicity arising from the tendency to minimize the area exposed to a…

Soft Condensed Matter · Physics 2012-06-12 Trinh X. Hoang , Jayanth R. Banavar , Amos Maritan