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Active learning (AL) has shown promise for being a particularly data-efficient machine learning approach. Yet, its performance depends on the application and it is not clear when AL practitioners can expect computational savings. Here, we…

Machine Learning · Computer Science 2024-08-22 Kunal Ghosh , Milica Todorović , Aki Vehtari , Patrick Rinke

Structure determination workloads in neutron diffractometry are computationally expensive and routinely require several hours to many days to determine the structure of a material from its neutron diffraction patterns. The potential for…

Machine Learning · Computer Science 2025-06-16 Tianle Wang , Jorge Ramirez , Cristina Garcia-Cardona , Thomas Proffen , Shantenu Jha , Sudip K. Seal

Abstract Interatomic potentials constitute the key component of large-scale atomistic simulations of materials. The recently proposed physically-informed neural network (PINN) method combines a high-dimensional regression implemented by an…

Computational Physics · Physics 2020-11-25 G. P. Purja Pun , V. Yamakov , J. Hickman , E. H. Glaessgen , Y. Mishin

Machine learned interatomic potentials (MLIPs) have emerged as powerful tools for molecular dynamics (MD) simulations with their competitive accuracy and computational efficiency. However, MLIPs are often observed to exhibit un-physical…

Materials Science · Physics 2026-02-24 Qianyu Zheng , Victor Fung

The convergence of statistical learning and molecular physics is transforming our approach to modeling biomolecular systems. Physics-informed machine learning (PIML) offers a systematic framework that integrates data-driven inference with…

Biomolecules · Quantitative Biology 2025-11-11 Aaryesh Deshpande

Machine-learning force fields enable an accurate and universal description of the potential energy surface of molecules and materials on the basis of a training set of ab initio data. However, large-scale applications of these methods rest…

Computational Physics · Physics 2023-07-25 Valerio Briganti , Alessandro Lunghi

Infrared (IR) spectroscopy is a pivotal analytical tool as it provides real-time molecular insight into material structures and enables the observation of reaction intermediates in situ. However, interpreting IR spectra often requires…

Chemical Physics · Physics 2025-06-17 Nitik Bhatia , Patrick Rinke , Ondrej Krejci

Building a question answering (QA) model with less annotation costs can be achieved by utilizing active learning (AL) training strategy. It selects the most informative unlabeled training data to update the model effectively. Acquisition…

Computation and Language · Computer Science 2023-11-07 Fan Luo , Mihai Surdeanu

The simulation of chemical reactions is an anticipated application of quantum computers. Using a Diels-Alder reaction as a test case, in this study we explore the potential applications of quantum algorithms and hardware in investigating…

Active learning (AL) is a human-and-model-in-the-loop paradigm that iteratively selects informative unlabeled data for human annotation, aiming to improve over random sampling. However, performing AL experiments with human annotations…

Machine Learning · Computer Science 2023-05-24 Katerina Margatina , Nikolaos Aletras

Computational chemistry tools are widely used to study the behaviour of chemical phenomena. Yet, the complexity of these tools can make them inaccessible to non-specialists and challenging even for experts. In this work, we introduce El…

Increasing demand for algorithms that can learn quickly and efficiently has led to a surge of development within the field of artificial intelligence (AI). An important paradigm within AI is reinforcement learning (RL), where agents…

Machine learning plays an increasingly important role in computational chemistry and materials science, complementing computationally intensive ab initio and first-principles methods. Despite their utility, machine-learning models often…

Chemical Physics · Physics 2025-05-06 Makoto Takamoto , Viktor Zaverkin , Mathias Niepert

Photo-induced processes are fundamental in nature, but accurate simulations are seriously limited by the cost of the underlying quantum chemical calculations, hampering their application for long time scales. Here we introduce a method…

Quantum information science and technology is a rapidly growing interdisciplinary field drawing researchers from science and engineering fields. Traditional instruction in quantum mechanics is insufficient to prepare students for research…

Physics Education · Physics 2016-02-23 Chandralekha Singh

The subject of this paper is the technology (the "how") of constructing machine-learning interatomic potentials, rather than science (the "what" and "why") of atomistic simulations using machine-learning potentials. Namely, we illustrate…

Computational Physics · Physics 2020-07-20 Ivan S. Novikov , Konstantin Gubaev , Evgeny V. Podryabinkin , Alexander V. Shapeev

High-fidelity physics simulations are powerful tools in the design and optimization of charged particle accelerators. However, the computational burden of these simulations often limits their use in practice for design optimization and…

Accelerator Physics · Physics 2020-04-15 Auralee Edelen , Nicole Neveu , Yannick Huber , Mattias Frey , Christopher Mayes , Andreas Adelmann

Kernel-based machine learning regression algorithms (MLRAs) are potentially powerful methods for being implemented into operational biophysical variable retrieval schemes. However, they face difficulties in coping with large training…

Signal Processing · Electrical Eng. & Systems 2020-12-16 ochem Verrelst , Sara Dethier , Juan Pablo Rivera , Jordi Muñoz-Marí , Gustau Camps-Valls , José Moreno

Machine learning potentials have revolutionised the field of atomistic simulations in recent years and are becoming a mainstay in the toolbox of computational scientists. This paper aims to provide an overview and introduction into machine…

Chemical Physics · Physics 2024-10-02 Fabian L. Thiemann , Niamh O'Neill , Venkat Kapil , Angelos Michaelides , Christoph Schran

Computational chemistry allows researchers to experiment in sillico: by running a computer simulations of a biological or chemical processes of interest. Molecular dynamics with molecular mechanics model of interactions simulates N-body…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-03-03 Jana Pazúriková