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Artificial intelligence (AI) systems utilizing deep neural networks (DNNs) and machine learning (ML) algorithms are widely used for solving important problems in bioinformatics, biomedical informatics, and precision medicine. However,…

Quantitative Methods · Quantitative Biology 2023-02-24 Md. Rezaul Karim , Tanhim Islam , Oya Beyan , Christoph Lange , Michael Cochez , Dietrich Rebholz-Schuhmann , Stefan Decker

We are used to the availability of big data generated in nearly all fields of science as a consequence of technological progress. However, the analysis of such data possess vast challenges. One of these relates to the explainability of…

Artificial Intelligence · Computer Science 2022-09-14 Frank Emmert-Streib , Olli Yli-Harja , Matthias Dehmer

Artificial Intelligence (AI) has become essential for analyzing complex data and solving highly-challenging tasks. It is being applied across numerous disciplines beyond computer science, including Food Engineering, where there is a growing…

Many ML models are opaque to humans, producing decisions too complex for humans to easily understand. In response, explainable artificial intelligence (XAI) tools that analyze the inner workings of a model have been created. Despite these…

Computers and Society · Computer Science 2021-06-17 Kiana Alikhademi , Brianna Richardson , Emma Drobina , Juan E. Gilbert

Explainable Artificial Intelligence (XAI) has experienced a significant growth over the last few years. This is due to the widespread application of machine learning, particularly deep learning, that has led to the development of highly…

Artificial Intelligence · Computer Science 2020-10-13 Giulia Vilone , Luca Longo

Explainable Artificial Intelligence (XAI) is an emerging research field bringing transparency to highly complex and opaque machine learning (ML) models. Despite the development of a multitude of methods to explain the decisions of black-box…

Machine Learning · Computer Science 2022-03-16 Leander Weber , Sebastian Lapuschkin , Alexander Binder , Wojciech Samek

Explainable Artificial Intelligence (XAI) techniques are frequently required by users in many AI systems with the goal of understanding complex models, their associated predictions, and gaining trust. While suitable for some specific tasks…

Human-Computer Interaction · Computer Science 2023-03-22 Savio Rozario , George Čevora

The integration of artificial intelligence (AI) into medicine is remarkable, offering advanced diagnostic and therapeutic possibilities. However, the inherent opacity of complex AI models presents significant challenges to their clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Binbin Wen , Yihang Wu , Tareef Daqqaq , Ahmad Chaddad

As systems based on opaque Artificial Intelligence (AI) continue to flourish in diverse real-world applications, understanding these black box models has become paramount. In response, Explainable AI (XAI) has emerged as a field of research…

With the availability of large databases and recent improvements in deep learning methodology, the performance of AI systems is reaching or even exceeding the human level on an increasing number of complex tasks. Impressive examples of this…

Artificial Intelligence · Computer Science 2017-08-29 Wojciech Samek , Thomas Wiegand , Klaus-Robert Müller

Artificial intelligence (AI) enables machines to learn from human experience, adjust to new inputs, and perform human-like tasks. AI is progressing rapidly and is transforming the way businesses operate, from process automation to cognitive…

Machine Learning · Computer Science 2021-12-17 Ambreen Hanif

The field of "explainable artificial intelligence" (XAI) seemingly addresses the desire that decisions of machine learning systems should be human-understandable. However, in its current state, XAI itself needs scrutiny. Popular methods…

Machine Learning · Computer Science 2026-04-09 Stefan Haufe , Rick Wilming , Benedict Clark , Rustam Zhumagambetov , Ahcène Boubekki , Jörg Martin , Danny Panknin

Explainable Artificial Intelligence (XAI) is essential for building advanced machine learning-powered applications, especially in critical domains such as medical diagnostics or autonomous driving. Legal, business, and ethical requirements…

Human-Computer Interaction · Computer Science 2024-10-17 Tobias Labarta , Elizaveta Kulicheva , Ronja Froelian , Christian Geißler , Xenia Melman , Julian von Klitzing

Recent applications of autonomous agents and robots, such as self-driving cars, scenario-based trainers, exploration robots, and service robots have brought attention to crucial trust-related challenges associated with the current…

Robotics · Computer Science 2022-09-26 Fatai Sado , Chu Kiong Loo , Wei Shiung Liew , Matthias Kerzel , Stefan Wermter

Modern AI systems frequently rely on opaque black-box models, most notably Deep Neural Networks, whose performance stems from complex architectures with millions of learned parameters. While powerful, their complexity poses a major…

Machine Learning · Computer Science 2026-02-23 David Dembinsky , Adriano Lucieri , Stanislav Frolov , Hiba Najjar , Ko Watanabe , Andreas Dengel

In the last years, Artificial Intelligence (AI) has achieved a notable momentum that may deliver the best of expectations over many application sectors across the field. For this to occur, the entire community stands in front of the barrier…

The adoption of intelligent systems creates opportunities as well as challenges for medical work. On the positive side, intelligent systems have the potential to compute complex data from patients and generate automated diagnosis…

Human-Computer Interaction · Computer Science 2019-02-19 Yao Xie , Ge Gao , Xiang 'Anthony' Chen

The advancements in deep learning-based methods for visual perception tasks have seen astounding growth in the last decade, with widespread adoption in a plethora of application areas from autonomous driving to clinical decision support…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Kumar Abhishek , Deeksha Kamath

The remarkable success of deep learning has prompted interest in its application to medical imaging diagnosis. Even though state-of-the-art deep learning models have achieved human-level accuracy on the classification of different types of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Cristiano Patrício , João C. Neves , Luís F. Teixeira