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Building accurate and interpretable Machine Learning (ML) models for heterogeneous/mixed data is a long-standing challenge for algorithms designed for numeric data. This work focuses on developing numeric coding schemes for non-numeric…

Machine Learning · Computer Science 2023-11-27 Boris Kovalerchuk , Elijah McCoy

Accurate modeling of the solvent environment for biological molecules is crucial for computational biology and drug design. A popular approach to achieve long simulation time scales for large system sizes is to incorporate the effect of the…

Computational Physics · Physics 2021-08-27 Yaoyi Chen , Andreas Krämer , Nicholas E. Charron , Brooke E. Husic , Cecilia Clementi , Frank Noé

Surface elasticity is central to understanding the mechanics and stability of surfaces and interfaces. It is characterized by quantities such as surface tension, residual surface stress, and surface stiffness, however their analytical…

Materials Science · Physics 2025-12-03 Saaketh Desai , Prasad P. Iyer , Remi Dingreville

Motivated by the remarkable success of artificial intelligence (AI) across diverse fields, the application of AI to solve scientific problems, often formulated as partial differential equations (PDEs), has garnered increasing attention.…

Machine Learning · Computer Science 2025-10-21 Rohan Bhatnagar , Ling Liang , Krish Patel , Haizhao Yang

A central question in machine learning is how reliable the predictions of a trained model are. Reliability includes the identification of instances for which a model is likely not to be trusted based on an analysis of the learning system…

Quantum Physics · Physics 2026-01-21 Marie Kempkes , Jakob Spiegelberg , Evert van Nieuwenburg , Vedran Dunjko

Many machine learning strategies designed to automate mathematical tasks leverage neural networks to search large combinatorial spaces of mathematical symbols. In contrast to traditional evolutionary approaches, using a neural network at…

Many risk-sensitive applications require Machine Learning (ML) models to be interpretable. Attempts to obtain interpretable models typically rely on tuning, by trial-and-error, hyper-parameters of model complexity that are only loosely…

Machine Learning · Computer Science 2020-05-29 Marco Virgolin , Andrea De Lorenzo , Eric Medvet , Francesca Randone

Machine learning approaches have become popular for molecular modeling tasks, including molecular force fields and properties prediction. Traditional supervised learning methods suffer from scarcity of labeled data for particular tasks,…

Chemical Physics · Physics 2022-11-29 Xiang Gao , Weihao Gao , Wenzhi Xiao , Zhirui Wang , Chong Wang , Liang Xiang

Symbolic regression is a powerful system identification technique in industrial scenarios where no prior knowledge on model structure is available. Such scenarios often require specific model properties such as interpretability, robustness,…

We consider the problem of retraining machine learning (ML) models when new batches of data become available. Existing approaches greedily optimize for predictive power independently at each batch, without considering the stability of the…

Machine Learning · Computer Science 2025-02-05 Dimitris Bertsimas , Vassilis Digalakis , Yu Ma , Phevos Paschalidis

Symbolic indefinite integration in Computer Algebra Systems such as Maple involves selecting the most effective algorithm from multiple available methods. Not all methods will succeed for a given problem, and when several do, the results,…

Symbolic Computation · Computer Science 2025-08-11 Rashid Barket , Matthew England , Jürgen Gerhard

In this paper, we present a machine learning method for the discovery of analytic solutions to differential equations. The method utilizes an inherently interpretable algorithm, genetic programming based symbolic regression. Unlike…

Machine Learning · Computer Science 2023-02-08 Hongsup Oh , Roman Amici , Geoffrey Bomarito , Shandian Zhe , Robert Kirby , Jacob Hochhalter

Machine learning (ML) has been leveraged to tackle a diverse range of tasks in almost all branches of nuclear engineering. Many of the successes in ML applications can be attributed to the recent performance breakthroughs in deep learning,…

Systems and Control · Electrical Eng. & Systems 2025-03-25 Xu Wu , Lesego E. Moloko , Pavel M. Bokov , Gregory K. Delipei , Joshua Kaizer , Kostadin N. Ivanov

Meta learning is a promising solution to few-shot learning problems. However, existing meta learning methods are restricted to the scenarios where training and application tasks share the same out-put structure. To obtain a meta model…

Machine Learning · Computer Science 2019-04-22 Yingtian Zou , Jiashi Feng

Most atomistic machine learning (ML) models rely on a locality ansatz, and decompose the energy into a sum of short-ranged, atom-centered contributions. This leads to clear limitations when trying to describe problems that are dominated by…

Symbolic regression automates the process of learning closed-form mathematical models from data. Standard approaches to symbolic regression, as well as newer deep learning approaches, rely on heuristic model selection criteria, heuristic…

Machine Learning · Statistics 2025-07-29 Roger Guimera , Marta Sales-Pardo

The ``black-box'' nature of deep learning models presents a significant barrier to their adoption for scientific discovery, where interpretability is paramount. This challenge is especially pronounced in discovering the governing equations…

Machine Learning · Computer Science 2025-08-26 Riccardo Cappi , Paolo Frazzetto , Nicolò Navarin , Alessandro Sperduti

Amorphous materials are coming within reach of realistic computer simulations, but new approaches are needed to fully understand their intricate atomic structures. Here, we show how machine-learning (ML)-based techniques can give new,…

Machine learning (ML) has emerged as a powerful tool for accelerating the computational design and production of materials. In materials science, ML has primarily supported large-scale discovery of novel compounds using first-principles…

Chemists in search of structure-property relationships face great challenges due to limited high quality, concordant datasets. Machine learning (ML) has significantly advanced predictive capabilities in chemical sciences, but these modern…

Machine Learning · Computer Science 2025-09-18 Yulia Pimonova , Michael G. Taylor , Alice Allen , Ping Yang , Nicholas Lubbers
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