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Recent advancements in AI applications to healthcare have shown incredible promise in surpassing human performance in diagnosis and disease prognosis. With the increasing complexity of AI models, however, concerns regarding their opacity,…
Most pregnancies and births result in a good outcome, but complications are not uncommon and when they do occur, they can be associated with serious implications for mothers and babies. Predictive modeling has the potential to improve…
Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…
Computer-aided diagnosis (CAD), a vibrant medical imaging research field, is expanding quickly. Because errors in medical diagnostic systems might lead to seriously misleading medical treatments, major efforts have been made in recent years…
Artificial Intelligence (AI) has demonstrated potential in healthcare, particularly in enhancing diagnostic accuracy and decision-making through Clinical Decision Support Systems (CDSSs). However, the successful implementation of these…
Although data-driven artificial intelligence (AI) in medical image diagnosis has shown impressive performance in silico, the lack of interpretability makes it difficult to incorporate the "black box" into clinicians' workflows. To make the…
Objective. Type 2 diabetes mellitus (T2DM) is a highly prevalent non-communicable chronic disease that substantially reduces life expectancy. Accurate estimation of all-cause mortality risk in T2DM patients is crucial for personalizing and…
Understanding and inferencing Heterogeneous Treatment Effects (HTE) and Conditional Average Treatment Effects (CATE) are vital for developing personalized treatment recommendations. Many state-of-the-art approaches achieve inspiring…
The healthcare industry generates enormous amounts of complex clinical data that make the prediction of disease detection a complicated process. In medical informatics, making effective and efficient decisions is very important. Data Mining…
Cardiovascular diseases state as one of the greatest risks of death for the general population. Late detection in heart diseases highly conditions the chances of survival for patients. Age, sex, cholesterol level, sugar level, heart rate,…
Survival modeling in healthcare relies on explainable statistical models; yet, their underlying assumptions are often simplistic and, thus, unrealistic. Machine learning models can estimate more complex relationships and lead to more…
Background and Objective: Incomplete Kawasaki disease (KD) has often been misdiagnosed due to a lack of the clinical manifestations of classic KD. However, it is associated with a markedly higher prevalence of coronary artery lesions.…
Jayasinghe et al. [Science of the Total Environment, 705 (2020) 135766] propose a 'dynamical' model of Chronic Kidney Disease of Unknown etiology (CKDu) wherein CKDu arises as an emergent property of a complex system where they claim that…
Worldwide, many millions of people die suddenly and unexpectedly each year, either with or without a prior history of cardiovascular disease. Such events are sparse (once in a lifetime), many victims will not have had prior investigations…
Cardiovascular diseases remain the leading global cause of mortality. Age is an important covariate whose effect is most easily investigated in a healthy cohort to properly distinguish the former from disease-related changes. Traditionally,…
Incurable diseases continue to pose major challenges to global healthcare systems, with their prevalence shaped by lifestyle, economic, social, and genetic factors. Among these, kidney disease remains a critical global health issue,…
Background: Several studies indicate that the anterior visual pathway provides information about the dynamics of axonal degeneration in Multiple Sclerosis (MS). Current research in the field is focused on the quest for the most…
Globally, Coronary Heart Disease (CHD) is one of the main causes of death. Early detection of CHD can improve patient outcomes and reduce mortality rates. We propose a novel framework for predicting the presence of CHD using a combination…
Cardiovascular diseases (CVDs) encompass a group of disorders affecting the heart and blood vessels, including conditions such as coronary artery disease, heart failure, stroke, and hypertension. In cardiovascular diseases, heart failure is…
Biomedical research has revealed the crucial role of miRNAs in the progression of many diseases, and computational prediction methods are increasingly proposed for assisting biological experiments to verify miRNA-disease associations…