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Understanding how genetic variants influence cellular-level processes is an important step towards understanding how they influence important organismal-level traits, or "phenotypes", including human disease susceptibility. To this end…

Methodology · Statistics 2013-07-30 Heejung Shim , Matthew Stephens

In recent years, considerable progress has been made in the visual quality of Generative Adversarial Networks (GANs). Even so, these networks still suffer from degradation in quality for high-frequency content, stemming from a spectrally…

Computer Vision and Pattern Recognition · Computer Science 2021-02-12 Rinon Gal , Dana Cohen , Amit Bermano , Daniel Cohen-Or

Large language models (LLMs) have achieved remarkable progress, yet their internal mechanisms remain largely opaque, posing a significant challenge to their safe and reliable deployment. Sparse autoencoders (SAEs) have emerged as a…

Computation and Language · Computer Science 2026-02-11 Jiaojiao Han , Wujiang Xu , Mingyu Jin , Mengnan Du

Computational biology has increasingly turned to agent-based modeling to explore complex biological systems. Biological diffusion (diffusion, decay, secretion, and uptake) is a key driver of biological tissues. GPU computing can vastly…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-10-27 Matt Stack , Paul Macklin , Robert Searles , Sunita Chandrasekaran

The recent surge in AI agents that autonomously communicate, collaborate with humans and use diverse tools has unlocked promising opportunities in various real-world settings. However, a vital aspect remains underexplored: how agents handle…

Machine Learning · Computer Science 2025-11-04 Nabeel Seedat , Jiashuo Liu , Mihaela van der Schaar

The arrival of large language models (LLMs) capable of multi-step reasoning, tool use, and long-horizon planning has produced a qualitative shift in software engineering. Where earlier code-completion tools such as GitHub Copilot operated…

Software Engineering · Computer Science 2026-04-30 Happy Bhati

End-to-end GUI agents for real desktop environments require large amounts of high-quality interaction data, yet collecting human demonstrations is expensive and existing synthetic pipelines often suffer from limited task diversity or noisy,…

Artificial Intelligence · Computer Science 2026-04-14 Jinbiao Wei , Yilun Zhao , Kangqi Ni , Arman Cohan

Computer use agents (CUAs) can operate real-world digital interfaces but remain difficult to train due to the high cost of graphical user interface (GUI) interaction and the scarcity of high-quality trajectory data. Existing datasets rely…

Machine Learning · Computer Science 2026-02-06 Yifei He , Pranit Chawla , Yaser Souri , Subhojit Som , Xia Song

Emerging AI accelerators increasingly adopt wafer-scale manufacturing technologies, integrating hundreds of thousands of AI cores in a mesh architecture with large distributed on-chip memory (tens of GB in total) and ultra-high on-chip…

Machine Learning · Computer Science 2025-06-02 Congjie He , Yeqi Huang , Pei Mu , Ziming Miao , Jilong Xue , Lingxiao Ma , Fan Yang , Luo Mai

Agent-based simulation is an indispensable paradigm for studying complex systems. These systems can comprise billions of agents, requiring the computing resources of multiple servers to simulate. Unfortunately, the state-of-the-art…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-09-30 Lukas Breitwieser , Ahmad Hesam , Abdullah Giray Yağlıkçı , Mohammad Sadrosadati , Fons Rademakers , Onur Mutlu

Agent-based modeling and network science have been used extensively to advance our understanding of emergent collective behavior in systems that are composed of a large number of simple interacting individuals or agents. With the increasing…

Multiagent Systems · Computer Science 2019-03-14 Marcos Cardinot , Colm O'Riordan , Josephine Griffith , Matjaž Perc

Recent image generation models have shown strong capabilities in generating high-fidelity and photorealistic images. However, they are fundamentally constrained by frozen internal knowledge, thus often failing on real-world scenarios that…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Kaituo Feng , Manyuan Zhang , Shuang Chen , Yunlong Lin , Kaixuan Fan , Yilei Jiang , Hongyu Li , Dian Zheng , Chenyang Wang , Xiangyu Yue

The Cerebras Wafer-Scale Engine (WSE) delivers performance at an unprecedented scale of over 900,000 compute units, all connected via a single-wafer on-chip interconnect. Initially designed for AI, the WSE architecture is also well-suited…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-27 Nicolai Stawinoga , David Katz , Anton Lydike , Justs Zarins , Nick Brown , George Bisbas , Tobias Grosser

Can AI accelerate the development of AI itself? While recent agentic systems have shown strong performance on well-scoped tasks with rapid feedback, it remains unclear whether they can tackle the costly, long-horizon, and weakly supervised…

Artificial Intelligence · Computer Science 2026-04-01 Weixian Xu , Tiantian Mi , Yixiu Liu , Yang Nan , Zhimeng Zhou , Lyumanshan Ye , Lin Zhang , Yu Qiao , Pengfei Liu

Feature selection is an intractable problem, therefore practical algorithms often trade off the solution accuracy against the computation time. In this paper, we propose a novel multi-stage feature selection framework utilizing multiple…

Machine Learning · Computer Science 2021-11-18 Mohammed Ghaith Altarabichi , Sławomir Nowaczyk , Sepideh Pashami , Peyman Sheikholharam Mashhad

As Large Language Models (LLMs) move from curated training sets into open-ended real-world environments, a fundamental limitation emerges: static training cannot keep pace with continual deployment environment change. Scaling training-time…

Artificial Intelligence · Computer Science 2026-03-17 Minhua Lin , Hanqing Lu , Zhan Shi , Bing He , Rui Mao , Zhiwei Zhang , Zongyu Wu , Xianfeng Tang , Hui Liu , Zhenwei Dai , Xiang Zhang , Suhang Wang , Benoit Dumoulin , Jian Pei

As sixth-generation (6G) wireless networks evolve toward increasingly heterogeneous scenarios, tasks, and service requirements, conventional artificial intelligence (AI) models remain limited in task-aware decision-making and autonomous…

Signal Processing · Electrical Eng. & Systems 2026-05-19 Mingyue Li , Li Yu , Yuxiang Zhang , Heng Wang , Jianhua Zhang , Ping Zhang , Guangyi Liu

Recent work explores agentic inference-time techniques to perform structured, multi-step reasoning. However, stateless inference often struggles on multi-step tasks due to the absence of persistent state. Moreover, task-specific fine-tuning…

Machine Learning · Computer Science 2025-10-09 Arshika Lalan , Rajat Ghosh , Aditya Kolsur , Debojyoti Dutta

We present AgentGA, a framework that evolves autonomous code-generation runs by optimizing the agent seed: the task prompt plus optional parent archives that initialize a fresh workspace. The outer loop searches over these reusable starting…

Artificial Intelligence · Computer Science 2026-05-12 David Y. Y. Tan , Kellie Chin , Jingxian Zhang

We present DARLEI, a framework that combines evolutionary algorithms with parallelized reinforcement learning for efficiently training and evolving populations of UNIMAL agents. Our approach utilizes Proximal Policy Optimization (PPO) for…

Artificial Intelligence · Computer Science 2023-12-11 Saeejith Nair , Mohammad Javad Shafiee , Alexander Wong