English
Related papers

Related papers: Guidelines for releasing a variant effect predicto…

200 papers

In ecological and environmental contexts, management actions must sometimes be chosen urgently. Value of information (VoI) analysis provides a quantitative toolkit for projecting the improved management outcomes expected after making…

Variance theories quantify the variance that one or more independent variables cause in a dependent variable. In software engineering (SE), variance theories are used to quantify -- among others -- the impact of tools, techniques, and other…

Software Engineering · Computer Science 2024-12-18 Julian Frattini , Jannik Fischbach , Davide Fucci , Michael Unterkalmsteiner , Daniel Mendez

Variational inference is a popular method for estimating model parameters and conditional distributions in hierarchical and mixed models, which arise frequently in many settings in the health, social, and biological sciences. Variational…

Methodology · Statistics 2019-01-10 Ted Westling , Tyler H. McCormick

Background: DNA, RNA, and protein sequence motifs can be recognition sites for biological functions such as regulation, DNA base modification, and molecular binding in general. The gain and loss of such motifs can carry important…

Genomics · Quantitative Biology 2022-10-19 Afif Elghraoui , Faramarz Valafar

We derive and present explicit algorithms to facilitate streamlined computing for variational inference for models containing higher level random effects. Existing literature, such as Lee and Wand (2016), is such that streamlined…

Computation · Statistics 2020-07-07 Tui H. Nolan , Marianne Menictas , Matt P. Wand

Variable Elimination (VE) is a classical exact inference algorithm for probabilistic graphical models such as Bayesian Networks, computing the marginal distribution of a subset of the random variables in the model. Our goal is to understand…

Logic in Computer Science · Computer Science 2025-01-28 Thomas Ehrhard , Claudia Faggian , Michele Pagani

Probabilistic forecasting in power systems often involves multi-entity datasets like households, feeders, and wind turbines, where generating reliable entity-specific forecasts presents significant challenges. Traditional approaches require…

Machine Learning · Computer Science 2025-06-27 Kutay Bölat , Simon Tindemans

Variational Bayes (VB) has become a widely-used tool for Bayesian inference in statistics and machine learning. Nonetheless, the development of the existing VB algorithms is so far generally restricted to the case where the variational…

Machine Learning · Computer Science 2021-08-04 Minh-Ngoc Tran , Dang H. Nguyen , Duy Nguyen

Vanilla variational inference finds an optimal approximation to the Bayesian posterior distribution, but even the exact Bayesian posterior is often not meaningful under model misspecification. We propose predictive variational inference…

Machine Learning · Statistics 2026-03-31 Jinlin Lai , Antonio Linero , Yuling Yao

Causal models communicate our assumptions about causes and effects in real-world phe- nomena. Often the interest lies in the identification of the effect of an action which means deriving an expression from the observed probability…

Machine Learning · Statistics 2018-06-20 Santtu Tikka , Juha Karvanen

Forecasting transmission of infectious diseases, especially for vector-borne diseases, poses unique challenges for researchers. Behaviors of and interactions between viruses, vectors, hosts, and the environment each play a part in…

Applications · Statistics 2020-06-02 Stephen A Lauer , Alexandria C Brown , Nicholas G Reich

Transformers for language modeling usually rely on deterministic internal computation, with uncertainty expressed mainly at the output layer. We introduce variational neurons into Transformer feed-forward computation so that uncertainty…

Machine Learning · Computer Science 2026-03-31 Yves Ruffenach

Varying coefficient models are useful in applications where the effect of the covariate might depend on some other covariate such as time or location. Various applications of these models often give rise to case-specific prior distributions…

Methodology · Statistics 2019-12-05 Maria Franco-Villoria , Massimo Ventrucci , Håvard Rue

Transformers, currently the state-of-the-art in natural language understanding (NLU) tasks, are prone to generate uncalibrated predictions or extreme probabilities, making the process of taking different decisions based on their output…

Computation and Language · Computer Science 2022-07-18 Patrizio Giovannotti

Machine learning applications require fast and reliable per-sample uncertainty estimation. A common approach is to use predictive distributions from Bayesian or approximation methods and additively decompose uncertainty into aleatoric…

Machine Learning · Computer Science 2026-02-10 H. Martin Gillis , Isaac Xu , Thomas Trappenberg

Variational Bayesian (VB) methods produce posterior inference in a time frame considerably smaller than traditional Markov Chain Monte Carlo approaches. Although the VB posterior is an approximation, it has been shown to produce good…

Computation · Statistics 2019-08-02 Nathaniel Tomasetti , Catherine S. Forbes , Anastasios Panagiotelis

We extend variational autoencoders (VAEs) to collaborative filtering for implicit feedback. This non-linear probabilistic model enables us to go beyond the limited modeling capacity of linear factor models which still largely dominate…

Machine Learning · Statistics 2018-02-19 Dawen Liang , Rahul G. Krishnan , Matthew D. Hoffman , Tony Jebara

As AI technology is increasingly applied to high-impact, high-risk domains, there have been a number of new methods aimed at making AI models more human interpretable. Despite the recent growth of interpretability work, there is a lack of…

Computer Vision and Pattern Recognition · Computer Science 2022-07-22 Sunnie S. Y. Kim , Nicole Meister , Vikram V. Ramaswamy , Ruth Fong , Olga Russakovsky

Predicting protein properties is paramount for biological and medical advancements. Current protein engineering mutates on a typical protein, called the wild-type, to construct a family of homologous proteins and study their properties.…

Machine Learning · Computer Science 2024-06-26 Zhiqiang Zhong , Davide Mottin

Analysis of high-dimensional data is currently a popular field of research, thanks to many applications e.g. in genetics (DNA data in genomewide association studies), spectrometry or web analysis. At the same time, the type of problems that…

Methodology · Statistics 2018-05-25 Jozef Jakubik