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Active learning (AL) seeks to reduce annotation costs by selecting the most informative samples for labeling, making it particularly valuable in resource-constrained settings. However, traditional evaluation methods, which focus solely on…

Machine Learning · Computer Science 2025-07-22 Julia Machnio , Mads Nielsen , Mostafa Mehdipour Ghazi

Pharmacometric models are pivotal across drug discovery and development, playing a decisive role in determining the progression of candidate molecules. However, the derivation of mathematical equations governing the system is a…

Machine Learning · Computer Science 2024-05-02 Imran Nasim , Adam Nasim

Active learning (AL) is a machine learning algorithm that can achieve greater accuracy with fewer labeled training instances, for having the ability to ask oracles to label the most valuable unlabeled data chosen iteratively and…

Machine Learning · Computer Science 2022-09-30 Ruoyu Wang

In the era of data-driven intelligence, the paradox of data abundance and annotation scarcity has emerged as a critical bottleneck in the advancement of machine learning. This paper gives a detailed overview of Active Learning (AL), which…

Machine Learning · Computer Science 2025-11-27 Chiung-Yi Tseng , Junhao Song , Ziqian Bi , Tianyang Wang , Chia Xin Liang , Xinyuan Song , Ming Liu

While deep learning (DL) is data-hungry and usually relies on extensive labeled data to deliver good performance, Active Learning (AL) reduces labeling costs by selecting a small proportion of samples from unlabeled data for labeling and…

Machine Learning · Computer Science 2022-07-20 Xueying Zhan , Qingzhong Wang , Kuan-hao Huang , Haoyi Xiong , Dejing Dou , Antoni B. Chan

Increasingly more research areas rely on machine learning methods to accelerate discovery while saving resources. Machine learning models, however, usually require large datasets of experimental or computational results, which in certain…

Machine Learning · Computer Science 2024-10-24 Elizaveta Surzhikova , Jonny Proppe

The versatility of multimodal deep learning holds tremendous promise for advancing scientific research and practical applications. As this field continues to evolve, the collective power of cross-modal analysis promises to drive…

Machine Learning · Computer Science 2025-05-15 Yifei Wang , Yunrui Li , Lin Liu , Pengyu Hong , Hao Xu

The task here is to predict the toxicological activity of chemical compounds based on the Tox21 dataset, a benchmark in computational toxicology. After a domain-specific overview of chemical toxicity, we discuss current computational…

Machine Learning · Computer Science 2025-10-28 Eduard Popescu , Adrian Groza , Andreea Cernat

The performance of multi-agent reinforcement learning (MARL) in partially observable environments depends on effectively aggregating information from observations, communications, and reward signals. While most existing multi-agent systems…

Multiagent Systems · Computer Science 2025-11-04 Qinwei Huang , Stefan Wang , Simon Khan , Garrett Katz , Qinru Qiu

Instruction tuning has shown promising potential for developing general-purpose AI capabilities by using large-scale pre-trained models and boosts growing research to integrate multimodal information for creative applications. However,…

Computation and Language · Computer Science 2023-12-21 Yihang Zhai , Haixin Wang , Jianlong Chang , Xinlong Yang , Jinan Sun , Shikun Zhang , Qi Tian

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

Machine Learning · Computer Science 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Machine learning (ML) models for predicting gas permeability through polymers have traditionally relied on experimental data. While these models exhibit robustness within familiar chemical domains, reliability wanes when applied to new…

Materials Science · Physics 2024-06-24 Brandon K. Phan , Kuan-Hsuan Shen , Rishi Gurnani , Huan Tran , Ryan Lively , Rampi Ramprasad

Functional peptides have the potential to treat a variety of diseases. Their good therapeutic efficacy and low toxicity make them ideal therapeutic agents. Artificial intelligence-based computational strategies can help quickly identify new…

Quantitative Methods · Quantitative Biology 2023-09-27 Zebin Ma , Yonglin Zou , Xiaobin Huang , Wenjin Yan , Hao Xu , Jiexin Yang , Ying Zhang , Jinqi Huang

The answers to many unsolved problems lie in the intractable chemical space of molecules and materials. Machine learning techniques are rapidly growing in popularity as a way to compress and explore chemical space efficiently. One of the…

Chemical Physics · Physics 2020-01-06 John E. Herr , Kevin Koh , Kun Yao , John Parkhill

Active Learning (AL) is a well-known standard method for efficiently obtaining annotated data by first labeling the samples that contain the most information based on a query strategy. In the past, a large variety of such query strategies…

Machine Learning · Computer Science 2025-03-13 Julius Gonsior , Maik Thiele , Wolfgang Lehner

Physics-informed machine learning (PIML) is a set of methods and tools that systematically integrate machine learning (ML) algorithms with physical constraints and abstract mathematical models developed in scientific and engineering…

This study employed an artificial intelligence-enhanced molecular simulation framework to enable efficient Path Integral Molecular Dynamics (PIMD) simulations. Owing to its modular architecture and high-throughput capabilities, the…

Chemical Physics · Physics 2025-04-01 Cheng Fan , Maodong Li , Sihao Yuan , Zhaoxin Xie , Dechin Chen , Yi Isaac Yang , Yi Qin Gao

We present several key advances to the Physics and Equality Constrained Artificial Neural Networks (PECANN) framework, substantially improving its capacity to solve challenging partial differential equations (PDEs). Our enhancements broaden…

Machine Learning · Computer Science 2025-12-09 Qifeng Hu , Shamsulhaq Basir , Inanc Senocak

Active learning (AL) is a prominent technique for reducing the annotation effort required for training machine learning models. Deep learning offers a solution for several essential obstacles to deploying AL in practice but introduces many…

Computation and Language · Computer Science 2022-05-10 Akim Tsvigun , Artem Shelmanov , Gleb Kuzmin , Leonid Sanochkin , Daniil Larionov , Gleb Gusev , Manvel Avetisian , Leonid Zhukov

Before taking actions in an environment with more than one intelligent agent, an autonomous agent may benefit from reasoning about the other agents and utilizing a notion of a guarantee or confidence about the behavior of the system. In…

Machine Learning · Computer Science 2024-02-12 Nikunj Gupta , Somjit Nath , Samira Ebrahimi Kahou