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Manually annotating nuclei from the gigapixel Hematoxylin and Eosin (H&E)-stained Whole Slide Images (WSIs) is a laborious and costly task, meaning automated algorithms for cell nuclei instance segmentation and classification could…

Computer Vision and Pattern Recognition · Computer Science 2024-07-29 João D. Nunes , Diana Montezuma , Domingos Oliveira , Tania Pereira , Jaime S. Cardoso

Instance segmentation is essential for numerous computer vision applications, including robotics, human-computer interaction, and autonomous driving. Currently, popular models bring impressive performance in instance segmentation by…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Cuong Manh Hoang

Surgical tool segmentation in endoscopic images is an important problem: it is a crucial step towards full instrument pose estimation and it is used for integration of pre- and intra-operative images into the endoscopic view. While many…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Daniil Pakhomov , Wei Shen , Nassir Navab

Weakly supervised nuclei segmentation is a critical problem for pathological image analysis and greatly benefits the community due to the significant reduction of labeling cost. Adopting point annotations, previous methods mostly rely on…

Image and Video Processing · Electrical Eng. & Systems 2022-02-14 Weizhen Liu , Qian He , Xuming He

The degree of malignancy of osteosarcoma and its tendency to metastasize/spread mainly depend on the pathological grade (determined by observing the morphology of the tumor under a microscope). The purpose of this study is to use artificial…

Image and Video Processing · Electrical Eng. & Systems 2022-05-02 Liangrui Pan , Hetian Wang , Lian Wang , Boya Ji , Mingting Liu , Mitchai Chongcheawchamnan , Jin Yuan , Shaoliang Peng

Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-17 Shanshan Wang , Cheng Li , Rongpin Wang , Zaiyi Liu , Meiyun Wang , Hongna Tan , Yaping Wu , Xinfeng Liu , Hui Sun , Rui Yang , Xin Liu , Jie Chen , Huihui Zhou , Ismail Ben Ayed , Hairong Zheng

Automatic segmentation of brain tumors in intra-operative ultrasound (iUS) images could facilitate localization of tumor tissue during resection surgery. The lack of large annotated datasets limits the current models performances. In this…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Mathilde Faanes , Ragnhild Holden Helland , Ole Solheim , Sébastien Muller , Ingerid Reinertsen

Image segmentation is a fundamental problem in biomedical image analysis. Recent advances in deep learning have achieved promising results on many biomedical image segmentation benchmarks. However, due to large variations in biomedical…

Computer Vision and Pattern Recognition · Computer Science 2017-06-16 Lin Yang , Yizhe Zhang , Jianxu Chen , Siyuan Zhang , Danny Z. Chen

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

With the advent of digital pathology and microscopic systems that can scan and save whole slide histological images automatically, there is a growing trend to use computerized methods to analyze acquired images. Among different…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Amirreza Mahbod , Georg Dorffner , Isabella Ellinger , Ramona Woitek , Sepideh Hatamikia

This paper focuses on drawing statistical inference based on a novel variant of maxima or minima nomination sampling (NS) designs. These sampling designs are useful for obtaining more representative sample units from the tails of the…

Methodology · Statistics 2021-06-01 Zeinab Akbari Ghamsari , Ehsan Zamanzade , Majid Asadi

Open-World Instance Segmentation (OWIS) is an emerging research topic that aims to segment class-agnostic object instances from images. The mainstream approaches use a two-stage segmentation framework, which first locates the candidate…

Computer Vision and Pattern Recognition · Computer Science 2022-10-19 Xizhe Xue , Dongdong Yu , Lingqiao Liu , Yu Liu , Satoshi Tsutsui , Ying Li , Zehuan Yuan , Ping Song , Mike Zheng Shou

Annotation variability remains a substantial challenge in medical image segmentation, stemming from ambiguous imaging boundaries and diverse clinical expertise. Traditional deep learning methods producing single deterministic segmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Han Zhang , Xiangde Luo , Yong Chen , Kang Li

Diagnosis based on medical images, such as X-ray images, often involves manual annotation of anatomical keypoints. However, this process involves significant human efforts and can thus be a bottleneck in the diagnostic process. To fully…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Jinhee Kim , Taesung Kim , Taewoo Kim , Jaegul Choo , Dong-Wook Kim , Byungduk Ahn , In-Seok Song , Yoon-Ji Kim

Medical image segmentation annotations exhibit variations among experts due to the ambiguous boundaries of segmented objects and backgrounds in medical images. Although using multiple annotations for each image in the fully-supervised has…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Shuai Wang , Tengjin Weng , Jingyi Wang , Yang Shen , Zhidong Zhao , Yixiu Liu , Pengfei Jiao , Zhiming Cheng , Yaqi Wang

Neural networks promise to bring robust, quantitative analysis to medical fields, but adoption is limited by the technicalities of training these networks. To address this translation gap between medical researchers and neural networks in…

Image and Video Processing · Electrical Eng. & Systems 2019-02-20 Brendon Lutnick , Brandon Ginley , Darshana Govind , Sean D. McGarry , Peter S. LaViolette , Rabi Yacoub , Sanjay Jain , John E. Tomaszewski , Kuang-Yu Jen , Pinaki Sarder

Nuclei instance segmentation in hematoxylin and eosin (H&E)-stained images plays an important role in automated histological image analysis, with various applications in downstream tasks. While several machine learning and deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

In surgical procedures, correct instrument counting is essential. Instance segmentation is a location method that locates not only an object's bounding box but also each pixel's specific details. However, obtaining mask-level annotations is…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Zhen Sun , Huan Xu , Jinlin Wu , Zhen Chen , Zhen Lei , Hongbin Liu

Consistent surgical instrument segmentation is critical for automation in robot-assisted surgery. Yet, existing methods only treat instrument-level instance segmentation (IIS) or part-level semantic segmentation (PSS) separately, without…

Computer Vision and Pattern Recognition · Computer Science 2025-07-29 Meng Wei , Charlie Budd , Oluwatosin Alabi , Miaojing Shi , Tom Vercauteren

In laparoscopic and robotic surgery, precise tool instance segmentation is an essential technology for advanced computer-assisted interventions. Although publicly available procedures of routine surgeries exist, they often lack…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Oluwatosin Alabi , Ko Ko Zayar Toe , Zijian Zhou , Charlie Budd , Nicholas Raison , Miaojing Shi , Tom Vercauteren