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In this paper, we study the problem of reconstructing a 3D point source model from a set of 2D projections at unknown view angles. Our method obviates the need to recover the projection angles by extracting a set of rotation-invariant…

Signal Processing · Electrical Eng. & Systems 2020-03-24 Mona Zehni , Shuai Huang , Ivan Dokmanić , Zhizhen Zhao

In this paper, we study a 2D tomography problem for point source models with random unknown view angles. Rather than recovering the projection angles, we reconstruct the model through a set of rotation-invariant features that are estimated…

Signal Processing · Electrical Eng. & Systems 2018-11-27 Mona Zehni , Shuai Huang , Ivan Dokmanić , Zhizhen Zhao

In parallel beam computed tomography (CT), an object is reconstructed from a series of projections taken at different angles. However, in some industrial and biomedical imaging applications, the projection geometry is unknown, completely or…

Image and Video Processing · Electrical Eng. & Systems 2025-12-23 Shreyas Jayant Grampurohit , Satish Mulleti , Ajit Rajwade

It is well known that a band-limited signal can be reconstructed from its uniformly spaced samples if the sampling rate is sufficiently high. More recently, it has been proved that one can reconstruct a 1D band-limited signal even if the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Sheel Shah , Kaishva Shah , Karthik S. Gurumoorthy , Ajit Rajwade

The goal of 2D tomographic reconstruction is to recover an image given its projections from various views. It is often presumed that projection angles associated with the projections are known in advance. Under certain situations, however,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-16 Mona Zehni , Zhizhen Zhao

In this paper, we present an algorithm for effectively reconstructing an object from a set of its tomographic projections without any knowledge of the viewing directions or any prior structural information, in the presence of pathological…

Image and Video Processing · Electrical Eng. & Systems 2019-06-12 Ritwick Chaudhry , Arunabh Ghosh , Ajit Rajwade

Cryo-Electron Microscopy (Cryo-EM) is a Nobel prize-winning technology for determining the 3D structure of particles at near-atomic resolution. A fundamental step in the recovering of the 3D single-particle structure is to align its 2D…

Image and Video Processing · Electrical Eng. & Systems 2021-01-12 Koby Bibas , Gili Weiss-Dicker , Dana Cohen , Noa Cahan , Hayit Greenspan

A single-particle cryo-electron microscopy (cryo-EM) measurement, called a micrograph, consists of multiple two-dimensional tomographic projections of a three-dimensional (3-D) molecular structure at unknown locations, taken under unknown…

Image and Video Processing · Electrical Eng. & Systems 2026-03-10 Shay Kreymer , Amit Singer , Tamir Bendory

Tomographic reconstruction recovers an unknown image given its projections from different angles. State-of-the-art methods addressing this problem assume the angles associated with the projections are known a-priori. Given this knowledge,…

Computer Vision and Pattern Recognition · Computer Science 2021-02-10 Mona Zehni , Zhizhen Zhao

Scientific imaging techniques such as optical and electron microscopy and computed tomography (CT) scanning are used to study the 3D structure of an object through 2D observations. These observations are related to the original 3D object…

Machine Learning · Computer Science 2019-06-21 Karen Ullrich , Rianne van den Berg , Marcus Brubaker , David Fleet , Max Welling

We formulate and investigate a statistical inverse problem of a random tomographic nature, where a probability density function on $\mathbb{R}^3$ is to be recovered from observation of finitely many of its two-dimensional projections in…

Statistics Theory · Mathematics 2009-09-03 Victor M. Panaretos

This paper concerns the problem of recovering an unknown but structured signal $x \in R^n$ from $m$ quadratic measurements of the form $y_r=|<a_r,x>|^2$ for $r=1,2,...,m$. We focus on the under-determined setting where the number of…

Machine Learning · Computer Science 2017-02-22 Mahdi Soltanolkotabi

Cryo-electron tomography (cryoET) is a technique that captures images of biological samples at different tilts, preserving their native state as much as possible. Along with the partial tilt series and noise, one of the major challenges in…

Signal Processing · Electrical Eng. & Systems 2023-07-26 Vinith Kishore , Valentin Debarnot , Ivan Dokmanić

A major challenge in single-particle cryo-electron microscopy (cryo-EM) is that the orientations adopted by the 3D particles prior to imaging are unknown; yet, this knowledge is essential for high-resolution reconstruction. We present a…

Machine Learning · Computer Science 2021-04-14 Jelena Banjac , Laurène Donati , Michaël Defferrard

Cryogenic electron microscopy (cryo-EM) provides images from different copies of the same biomolecule in arbitrary orientations. Here, we present an end-to-end unsupervised approach that learns individual particle orientations from cryo-EM…

Image and Video Processing · Electrical Eng. & Systems 2021-07-08 Youssef S. G. Nashed , Frederic Poitevin , Harshit Gupta , Geoffrey Woollard , Michael Kagan , Chuck Yoon , Daniel Ratner

Cryogenic electron tomography is a technique for imaging biological samples in 3D. A microscope collects a series of 2D projections of the sample, and the goal is to reconstruct the 3D density of the sample called the tomogram.…

Computer Vision and Pattern Recognition · Computer Science 2024-08-13 Simon Wiedemann , Reinhard Heckel

We propose a framework to jointly determine the deformation parameters and reconstruct the unknown volume in electron cryotomography (CryoET). CryoET aims to reconstruct three-dimensional biological samples from two-dimensional projections.…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Valentin Debarnot , Sidharth Gupta , Konik Kothari , Ivan Dokmanic

In this paper, we present an algorithm for effectively reconstructing an object from a set of its tomographic projections without any knowledge of the viewing directions or any prior structural information, in the presence of pathological…

Image and Video Processing · Electrical Eng. & Systems 2018-11-13 Ritwick Chaudhry , Arunabh Ghosh , Ajit Rajwade

We propose a method to reconstruct the 3-D molecular structure from micrographs collected at just one sample tilt angle in the random conical tilt scheme in cryo-electron microscopy. Our method uses autocorrelation analysis on the…

Data Analysis, Statistics and Probability · Physics 2021-01-12 Ti-Yen Lan , Nicolas Boumal , Amit Singer

In computed tomography, the reconstruction is typically obtained on a voxel grid. In this work, however, we propose a mesh-based reconstruction method. For tomographic problems, 3D meshes have mostly been studied to simulate data…

Image and Video Processing · Electrical Eng. & Systems 2021-03-12 Jakeoung Koo , Anders B. Dahl , J. Andreas Bærentzen , Qiongyang Chen , Sara Bals , Vedrana A. Dahl
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