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With the rapid advances of data acquisition techniques, spatio-temporal data are becoming increasingly abundant in a diverse array of disciplines. Here we develop spatio-temporal regression methodology for analyzing large amounts of…

Methodology · Statistics 2021-12-01 Ting Fung Ma , Fangfang Wang , Jun Zhu , Anthony R. Ives , Katarzyna E. Lewińska

A key challenge in environmental health research is unmeasured spatial confounding, driven by unobserved spatially structured variables that influence both treatment and outcome. A common approach is to fit a spatial regression that models…

Methodology · Statistics 2025-12-23 Sophie M. Woodward , Francesca Dominici , Jose R. Zubizarreta

In this paper, we aim to improve multivariate anomaly detection (AD) by modeling the \textit{time-varying non-linear spatio-temporal correlations} found in multivariate time series data . In multivariate time series data, an anomaly may be…

Machine Learning · Computer Science 2025-09-19 Padmaksha Roy , Almuatazbellah Boker , Lamine Mili

Several algorithms have been proposed for discovering patterns from trajectories of moving objects, but only a few have concentrated on outlier detection. Existing approaches, in general, discover spatial outliers, and do not provide any…

Artificial Intelligence · Computer Science 2013-03-22 Vitor Cunha Fontes , Vania Bogorny

Spatial scan statistics are well-known methods for cluster detection and are widely used in epidemiology and medical studies for detecting and evaluating the statistical significance of disease hotspots. For the sake of simplicity, the…

Methodology · Statistics 2019-11-25 Mohamed-Salem Ahmed , Lionel Cucala , Michael Genin

Surveillance data serving for epidemic alert systems are typically fully aggregated in space. However, epidemics may be spatially heterogeneous, undergoing distinct dynamics in distinct regions of the surveillance area. We unveil this in…

Populations and Evolution · Quantitative Biology 2018-03-30 Pavel Polyakov , Cécile Souty , Pierre-Yves Böelle , Romulus Breban

With the increased availability of large databases of electronic health records (EHRs) comes the chance of enhancing health risks screening. Most post-marketing detections of adverse drug reaction (ADR) rely on physicians' spontaneous…

Applications · Statistics 2018-01-29 Maryan Morel , Emmanuel Bacry , Stéphane Gaïffas , Agathe Guilloux , Fanny Leroy

Approaches to the calculation of the full state vector of a larger epidemiological model for the spread of COVID-19 in Sweden at the initial time instant from available data and with a simplified dynamical model are proposed and evaluated.…

Systems and Control · Electrical Eng. & Systems 2020-07-20 Håkan Runvik , Alexander Medvedev , Robin Eriksson , Stefan Engblom

With the outbreak of the COVID-19 pandemic, various studies have focused on predicting the trajectory and risk factors of the virus and its variants. Building on previous work that addressed this problem using genetic and epidemiological…

Applications · Statistics 2023-12-25 Catherine Li , Daniel Lazarev

This study addresses the challenges of symptom evolution complexity and insufficient temporal dependency modeling in Parkinson's disease progression prediction. It proposes a unified prediction framework that integrates structural…

Machine Learning · Computer Science 2025-08-22 Jiacheng Hu , Bo Zhang , Ting Xu , Haifeng Yang , Min Gao

Causal discovery is the subfield of causal inference concerned with estimating the structure of cause-and-effect relationships in a system of interrelated variables, as opposed to quantifying the strength or describing the form of causal…

Methodology · Statistics 2026-03-26 Rebecca F. Supple , Hannah Worthington , Ben Swallow

Normative modeling enables individualized characterization of structural brain deviations by evaluating subjects against a reference population rather than a group average. Most existing implementations treat brain regions independently and…

Methodology · Statistics 2026-05-19 J. T. Korley

This paper introduces area-level Poisson mixed models with temporal and SAR(1) spatially correlated random effects. Small area predictors of the proportions and counts of a dichotomic variable are derived from the new models and the…

Methodology · Statistics 2020-12-02 M. Boubeta , M. J. Lombardía , F. Marey-Pérez , D. Morales

Dynamic properties of spreading infection through a heterogeneous population are studied numerically and analytically using a dynamic variant of Watts and Strogatz Small World Network-based stochastic Susceptible-Exposed-Infectious-Removed…

Populations and Evolution · Quantitative Biology 2019-06-28 O. Mosbah , N. Zekri , M. Mokhtari , S. Sahraoui

Marginal structural models (MSMs) are widely used in observational studies to estimate the causal effect of time-varying treatments. Despite its popularity, limited attention has been paid to summarizing the treatment history in the outcome…

Methodology · Statistics 2024-09-18 Jiewen Liu , Todd A. Miano , Stephen Griffiths , Michael G. S. Shashaty , Wei Yang

In this paper, we propose a novel approach for outlier detection, called local projections, which is based on concepts of Local Outlier Factor (LOF) (Breunig et al., 2000) and RobPCA (Hubert et al., 2005). By using aspects of both methods,…

We propose a forecasting method for predicting epidemiological health series on a two-week horizon at the regional and interregional resolution. The approach is based on model order reduction of parametric compartmental models, and is…

Methodology · Statistics 2020-12-11 Athmane Bakhta , Thomas Boiveau , Yvon Maday , Olga Mula

Spatial documentation is exponentially increasing given the availability of Big IoT Data, enabled by the devices miniaturization and data storage capacity. Bayesian spatial statistics is a useful statistical tool to determine the dependence…

Methodology · Statistics 2020-10-01 Francisco Louzada , Diego C. Nascimento , Osafu Augustine Egbon

The coronavirus pandemic has rapidly evolved into an unprecedented crisis. The susceptible-infectious-removed (SIR) model and its variants have been used for modeling the pandemic. However, time-independent parameters in the classical…

Populations and Evolution · Quantitative Biology 2020-09-09 Hyokyoung G. Hong , Yi Li

Despite the amount of research on disease mapping in recent years, the use of multivariate models for areal spatial data remains limited due to difficulties in implementation and computational burden. These problems are exacerbated when the…

Methodology · Statistics 2023-07-24 G. Vicente , A. Adin , T. Goicoa , M. D. Ugarte