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The ABC (ATP Binding Cassette) transporter protein superfamily comprises a large number of ubiquitous and functionally versatile proteins conserved from archaea to humans. ABC transporters have a key role in many human diseases and also in…

Molecular Networks · Quantitative Biology 2013-09-18 Tamas Hegedus , Gergely Gyimesi , Merse E. Gaspar , Kristof Z. Szalay , Rajeev Gangal , Peter Csermely

Tactile sensing plays an important role in robotic perception and manipulation. To overcome the real-world limitations of data collection, simulating tactile response in virtual environment comes as a desire direction of robotic research.…

Robotics · Computer Science 2020-11-24 Yikai Wang , Wenbing Huang , Bin Fang , Fuchun Sun

Interaction of electric fields with biological cells is indispensable for many physiological processes. Thermal electrical noise in the cellular environment has long been considered as the minimum threshold for detection of electrical…

Soft Condensed Matter · Physics 2026-02-24 Anand Mathew , Yashashree Kulkarni

The effect of interactions on dynamics of coupled motor proteins is investigated theoretically. A simple stochastic discrete model, that allows to calculate explicitly the dynamic properties of the system, is developed. It is shown that…

Soft Condensed Matter · Physics 2009-11-11 Evgeny B. Stukalin , Anatoly B. Kolomeisky

Understanding how transcription factors (TFs) regulate mammalian gene expression in space and time is a central topic in biology. To activate a gene, a TF has first to diffuse in the available space of the nucleus until it reaches a target…

Subcellular Processes · Quantitative Biology 2018-11-19 Maxime Woringer , Xavier Darzacq

The interface of a cholesteric liquid crystal with an isotropic fluid can display a range of unusual properties, such as a layer of topological defects close to an undulated interface. These properties have been know for a long time and…

Soft Condensed Matter · Physics 2014-07-02 N. R. Bernardino , M. C. F. Pereira , N. M. Silvestre , M. M. Telo da Gama

RNA/protein interactions play crucial roles in controlling gene expression. They are becoming important targets for pharmaceutical applications. Due to RNA flexibility and to the strength of electrostatic interactions, standard docking…

Biomolecules · Quantitative Biology 2013-07-23 Trang N. Do , Paolo Carloni , Gabriele Varani , Giovanni Bussi

We analyze both the static and dynamic fluctuation spectrum of the red-blood cell in a unified manner, using a simple model of the composite membrane. In this model, the two-dimensional spectrin network that forms the cytoskeleton is…

Soft Condensed Matter · Physics 2007-05-23 N. Gov , A. G. Zilman , S. Safran

Tactile sensation is essential for humans to recognize objects. Various devices have been developed in the past for tactile presentation by electrostatic force, which are easy to configure devices, but there is currently no such device that…

Human-Computer Interaction · Computer Science 2024-10-08 Naoto Takayanagi , Naoji Matsuhisa , Yuki Hashimoto , Yuta Sugiura

The collaboration between humans and robots is critical in many robotic applications, especially in those requiring physical human-robot interaction (pHRI). Previous research in pHRI has largely focused on robotic manipulators, employing…

Robotics · Computer Science 2026-05-11 Shuai Li , Ton T. H. Duong , Damiano Zanotto

Non structural protein 3 (NS3) helicase from hepatitis C virus is an enzyme that unwinds and translocates along nucleic acids with an ATP-dependent mechanism and has a key role in the replication of the viral RNA. An inchworm-like mechanism…

Biomolecules · Quantitative Biology 2016-01-06 Andrea Pérez-Villa , Maria Darvas , Giovanni Bussi

We study the onset of dissipation in an atomic Josephson junction between Fermi superfluids in the molecular Bose-Einstein condensation limit of strong attraction. Our simulations identify the critical population imbalance and the maximum…

Semiflexible polymers such as filamentous actin play a vital role in the mechanical behavior of cells, yet the basic properties of cross-linked F-actin networks remain poorly understood. To address this issue, we have performed numerical…

Soft Condensed Matter · Physics 2009-11-10 D. A. Head , A. J. Levine , F. C. MacKintosh

he relationship between photoemission spectra of high-$T_{\textrm{c}}$ cuprates and their thermodynamic and transport properties are discussed. The doping dependence of the expected quasi-particle density at the Fermi level ($E_\mathrm{F}$)…

Cell-penetrating peptides (CPPs) such as HIV's trans-activating transcriptional activator (TAT) and polyarginine rapidly pass through the plasma membranes of mammalian cells by an unknown mechanism called transduction. They may be medically…

Biomolecules · Quantitative Biology 2010-09-21 Kevin Cahill

A model of a finite cylindrical ion channel through a phospholipid membrane of width $L$ separating two electrolyte reservoirs is studied. Analytical solution of the Poisson equation is obtained for an arbitrary distribution of ions inside…

Soft Condensed Matter · Physics 2009-11-11 Yan Levin

Vascular adhesion of circulating tumor cells (CTCs) is a key step in cancer spreading. If inflammation is recognized to favor the formation of vascular metastatic niches, little is known about the contribution of blood rheology to CTC…

Whether live cell membranes show miscibility phase transitions (MPTs), and if so, how they fluctuate near the transitions remain outstanding unresolved issues in physics and biology alike. Motivated by these questions we construct a generic…

Soft Condensed Matter · Physics 2017-12-01 Tirthankar Banerjee , Abhik Basu

Biomembranes are thin capacitors with the unique feature of displaying phase transitions in a physiologically relevant regime. We investigate the voltage and lateral pressure dependence of their capacitance close to their chain melting…

Biological Physics · Physics 2012-09-18 Thomas Heimburg

Biological systems tightly regulate their physiological state using control signals. This includes the actomyosin cytoskeleton, a contractile active gel that consumes chemical free energy to drive many examples of cellular mechanical…

Soft Condensed Matter · Physics 2025-03-03 James Clarke , Francis Cavanna , Aniket Marne , Anthony Davolio , José Alvarado