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ATP-driven proton pumps, which are critical to the operation of a cell, maintain cytosolic and organellar pH levels within a narrow functional range. These pumps employ two very different mechanisms: an elaborate rotary mechanism used by…

Subcellular Processes · Quantitative Biology 2017-11-01 Ramu Anandakrishnan , Daniel M. Zuckerman

Probably the most enticing observation in theoretical physics during the last decade was the discovery of the great amount of consequences obtained from the AdS/CFT conjecture put forward by Maldacena. In this work we review how this…

High Energy Physics - Theory · Physics 2017-08-23 Antonio Dobado , Felipe J. Llanes-Estrada , Juan M. Torres-Rincon

Cell mechanical functions like locomotion, contraction and division are controlled by the cytoskeleton, a dynamic biopolymer network whose mechanical properties remain poorly understood. We perform single-cell uniaxial stretching…

Biological Physics · Physics 2007-05-23 Pablo Fernandez , Pramod A. Pullarkat , Albrecht Ott

Tris(hydroxymethyl)aminomethane (Tris) has been used as the buffer in bioactivity testing for over two decades and has become a standard choice for the scientific community. While it is believed to be non-interacting, the extent of its…

Medical Physics · Physics 2021-03-30 Azade YazdanYar , Léa Buswell , Delphin Pantaloni , Ulrich Aschauer , Paul Bowen

Here we generalize our previous model of molecular motors trafficking subdiffusing cargos in viscoelastic cytosol by (i) including mechanochemical coupling between cyclic conformational fluctuations of the motor protein driven by the…

Biological Physics · Physics 2015-05-01 Igor Goychuk

When interacting two-dimensional electrons are placed in a large perpendicular magnetic field, to minimize their energy, they capture an even number of flux quanta and create new particles called composite fermions (CFs). These complex…

Mesoscale and Nanoscale Physics · Physics 2011-03-28 T. Gokmen , Medini Padmanabhan , M. Shayegan

We explore the transport properties of an interacting Fermi gas in a three-dimensional optical lattice. The center of mass dynamics of the atoms after a sudden displacement of the trap minimum is monitored for different interaction…

Strongly Correlated Electrons · Physics 2007-12-05 Niels Strohmaier , Yosuke Takasu , Kenneth Günter , Robert Jördens , Michael Köhl , Henning Moritz , Tilman Esslinger

The thermodynamic (TD) properties of biological membranes play a central role for living systems. It has been suggested, for instance, that nonlinear pulses such as action potentials (APs) can only exist if the membrane state is in vicinity…

Biological Physics · Physics 2020-07-16 Christian Fillafer , Anne Paeger , Matthias F. Schneider

Biological cells in soft materials can be modeled as anisotropic force contraction dipoles. The corresponding elastic interaction potentials are long-ranged ($\sim 1/r^3$ with distance $r$) and depend sensitively on elastic constants,…

Soft Condensed Matter · Physics 2009-11-07 U. S. Schwarz , S. A. Safran

FoF1-ATP synthases are ubiquitous membrane-bound, rotary motor enzymes that can catalyze ATP synthesis and hydrolysis. Their enzyme kinetics are controlled by internal subunit rotation, by substrate and product concentrations, by mechanical…

Biomolecules · Quantitative Biology 2021-06-29 Thomas Heitkamp , Michael Börsch

Under the most common experimental conditions, the adsorption of proteins to solid surfaces is an spontaneous process that leads to a rather compact layer of randomly oriented molecules. Due to the importance of this process for the…

Soft Condensed Matter · Physics 2022-06-29 Sergio A. Urzúa , Perla Y. Sauceda-Oloño , Carlos D. García , Christopher D. Cooper

We consider the lateral diffusion of a protein interacting with the curvature of the membrane. The interaction energy is minimized if the particle is at a membrane position with a certain curvature that agrees with the spontaneous curvature…

Soft Condensed Matter · Physics 2008-12-10 Stefan M. Leitenberger , Ellen Reister-Gottfried , Udo Seifert

G-protein coupled receptors (GPCRs), a major gatekeeper of extracellular signals on plasma membrane, are unarguably one of the most important therapeutic targets. Given the recent discoveries of allosteric modulations, an allosteric wiring…

Biomolecules · Quantitative Biology 2013-10-16 Yoonji Lee , Sun Choi , Changbong Hyeon

Antagonistic artificial muscles can decouple joint torque and stiffness, but contact transients often degrade this independence. We present a unified real-time framework applicable across pneumatic, electrohydraulic, and dielectric…

Robotics · Computer Science 2026-04-07 Amirhossein Kazemipour , Robert K. Katzschmann

Understanding the molecular mechanisms driving the binding between bio-molecules is a crucial challenge in molecular biology. In this respect, characteristics like the preferentially hydrophobic composition of the binding interfaces, the…

The synthetic actin network arouses great interest as bio-material due to its soft and wet nature that mimics many biological scaffolding structures. Inside the cell, the actin network is regulated by tens of actin-binding proteins (ABP's),…

Soft Condensed Matter · Physics 2019-03-19 Horacio Lopez-Menendez

In this work we study the assisted translocation of a polymer across a membrane nanopore, inside which a molecular motor exerts a force fuelled by the hydrolysis of ATP molecules. In our model the motor switches to its active state for a…

Soft Condensed Matter · Physics 2018-03-26 A. Fiasconaro , J. J. Mazo , F. Falo

Aqueous two-phase systems (ATPSs), that is, phase-separating solutions of water soluble but mutually immiscible molecular species, offer fascinating prospects for selective partitioning, purification, and extraction. Here, we formulate a…

Soft Condensed Matter · Physics 2023-11-29 Alberto Scacchi , Carlo Rigoni , Mikko Haataja , Jaakko V. I. Timonen , Maria Sammalkorpi

We report on the discovery of a quantum tri-critical point (QTP) separating a line of first-order topological quantum phase transitions from a continuous transition regime in a strongly correlated one-dimensional lattice system.…

Strongly Correlated Electrons · Physics 2019-03-06 S. Barbarino , G. Sangiovanni , J. C. Budich

Charge transfer plasmon (CTP) modes arise when metallic nanoparticles are connected by a conductive junction. These ultatunable plasmonic modes can be actively tuned and broadly modulated from visible to IR regimes, implying their…

Optics · Physics 2023-05-23 Alemayehu Nana Koya , Wei Li
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