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Infectious disease surveillance is of great importance for the prevention of major outbreaks. Syndromic surveillance aims at developing algorithms which can detect outbreaks as early as possible by monitoring data sources which allow to…

Machine Learning · Computer Science 2021-02-01 Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

Quantitative Methods · Quantitative Biology 2011-10-24 Alex Skvortsov , Branko Ristic

Early Warning Signals (EWSs) are vital for implementing preventive measures before a disease turns into a pandemic. While new diseases exhibit unique behaviors, they often share fundamental characteristics from a dynamical systems…

Machine Learning · Computer Science 2025-01-15 Reza Miry , Amit K. Chakraborty , Russell Greiner , Mark A. Lewis , Hao Wang , Tianyu Guan , Pouria Ramazi

Early outbreak detection is a key aspect in the containment of infectious diseases, as it enables the identification and isolation of infected individuals before the disease can spread to a larger population. Instead of detecting unexpected…

Machine Learning · Computer Science 2021-10-19 Michael Rapp , Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

Early outbreak data analysis is critical for informing about their potential impact and interventions. However, data obtained early in outbreaks are often sensitive and subject to strict privacy restrictions. Thus, federated analysis, which…

Applications · Statistics 2026-01-27 Simon Busch-Moreno , Moritz U. G. Kraemer

The Bayesian analysis of infectious disease surveillance data from multiple locations typically involves building and fitting a spatio-temporal model of how the disease spreads in the structured population. Here we present new generally…

Methodology · Statistics 2025-03-04 Matthew Adeoye , Xavier Didelot , Simon EF Spencer

Mathematical models in epidemiology are an indispensable tool to determine the dynamics and important characteristics of infectious diseases. Apart from their scientific merit, these models are often used to inform political decisions and…

Infectious diseases occur when pathogens from other individuals or animals infect a person, resulting in harm to both individuals and society as a whole. The outbreak of such diseases can pose a significant threat to human health. However,…

Populations and Evolution · Quantitative Biology 2024-10-24 Ghazaleh Babanejaddehaki , Aijun An , Manos Papagelis

We propose a framework for Bayesian non-parametric estimation of the rate at which new infections occur assuming that the epidemic is partially observed. The developed methodology relies on modelling the rate at which new infections occur…

Methodology · Statistics 2014-12-16 Edward S. Knock , Theodore Kypraios

This chapter surveys univariate and multivariate methods for infectious disease outbreak detection. The setting considered is a prospective one: data arrives sequentially as part of the surveillance systems maintained by public health…

Methodology · Statistics 2017-11-27 Benjamin Allévius , Michael Höhle

Non-pharmaceutical interventions, such as contact tracing and social distancing, are critical for controlling epidemic outbreaks, yet their dynamic interactions remain underexplored. We introduce a probabilistic framework to analyze the…

Physics and Society · Physics 2025-12-11 Jinghui Wang , Yutian Zeng , Cong Xu , Xiyun Zhang , Zhanwei Du , Jiarong Xie , Jiu Zhang , Sen Pei , Zijian Feng , Yanqing Hu

Early estimates of the transmission potential of emerging and re-emerging infections are increasingly used to inform public health authorities on the level of risk posed by outbreaks. Existing methods to estimate the reproduction number…

Quantitative Methods · Quantitative Biology 2016-10-10 Gerardo Chowell , Cécile Viboud , Lone Simonsen , Seyed Moghadas

In the wake of the SARS-CoV-2 pandemic, there has been heightened interest from applied mathematicians in infectious disease modelling. Modelling efforts often focus on predicting whether diseases are likely to be eliminated or, instead,…

Populations and Evolution · Quantitative Biology 2026-01-22 Joshua Looker , Kat S. Rock , Louise Dyson

The timely identification of socio-economic sectors vulnerable to a disease outbreak presents an important challenge to the civic authorities and healthcare workers interested in outbreak mitigation measures. This problem was traditionally…

Machine Learning · Computer Science 2021-10-28 Aboli Marathe , Harsh Sakhrani , Saloni Parekh

Understanding how epidemics spread in a system is a crucial step to prevent and control outbreaks, with broad implications on the system's functioning, health, and associated costs. This can be achieved by identifying the elements at higher…

Physics and Society · Physics 2015-03-16 Eugenio Valdano , Chiara Poletto , Armando Giovannini , Diana Palma , Lara Savini , Vittoria Colizza

Irregular multivariate time series with missing values present significant challenges for predictive modeling in domains such as healthcare. While deep learning approaches often focus on temporal interpolation or complex architectures to…

Machine Learning · Computer Science 2026-03-16 Dingyi Nie , Yixing Wu , C. -C. Jay Kuo

Epidemiologists use a variety of statistical algorithms for the early detection of outbreaks. The practical usefulness of such methods highly depends on the trade-off between the detection rate of outbreaks and the chances of raising a…

Machine Learning · Computer Science 2019-07-18 Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

Out-of-distribution (OOD) detection is essential for determining when a supervised model encounters inputs that differ meaningfully from its training distribution. While widely studied in classification, OOD detection for regression and…

Machine Learning · Statistics 2025-12-16 Min Lu , Hemant Ishwaran

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

Infectious disease outbreaks recapitulate biology: they emerge from the multi-level interaction of hosts, pathogens, and their shared environment. As a result, predicting when, where, and how far diseases will spread requires a complex…

Physics and Society · Physics 2018-10-11 Samuel V. Scarpino , Giovanni Petri
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