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Diagnosing basal cell carcinomas (BCC), one of the most common cutaneous malignancies in humans, is a task regularly performed by pathologists and dermato-pathologists. Improving histological diagnosis by providing diagnosis suggestions,…

The proliferation of early diagnostic technologies, including self-monitoring systems and wearables, coupled with the application of these technologies on large segments of healthy populations may significantly aggravate the problem of…

Machine Learning · Computer Science 2021-07-23 Anna Fedyukova , Douglas Pires , Daniel Capurro

Background: Medical decision-making impacts both individual and public health. Clinical scores are commonly used among a wide variety of decision-making models for determining the degree of disease deterioration at the bedside. AutoScore…

Sepsis is a life-threatening condition which requires rapid diagnosis and treatment. Traditional microbiological methods are time-consuming and expensive. In response to these challenges, deep learning algorithms were developed to identify…

Globally, in 2016, one out of eleven adults suffered from Diabetes Mellitus. Diabetic Foot Ulcers (DFU) are a major complication of this disease, which if not managed properly can lead to amputation. Current clinical approaches to DFU…

Computer Vision and Pattern Recognition · Computer Science 2017-12-12 Manu Goyal , Neil D. Reeves , Adrian K. Davison , Satyan Rajbhandari , Jennifer Spragg , Moi Hoon Yap

Sepsis, a dysregulated immune system response to infection, is among the leading causes of morbidity, mortality, and cost overruns in the Intensive Care Unit (ICU). Early prediction of sepsis can improve situational awareness amongst…

Machine Learning · Computer Science 2019-08-14 Supreeth P. Shashikumar , Christopher Josef , Ashish Sharma , Shamim Nemati

Assessing chronic pain behavior in mice is critical for preclinical studies. However, existing methods mostly rely on manual labeling of behavioral features, and humans lack a clear understanding of which behaviors best represent chronic…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Yu-Hsi Chen , Wei-Hsin Chen , Chien-Yao Wang , Hong-Yuan Mark Liao , James C. Liao , Chien-Chang Chen

Unsupervised video-based surgical instrument segmentation has the potential to accelerate the adoption of robot-assisted procedures by reducing the reliance on manual annotations. However, the generally low quality of optical flow in…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Yang Liu , Peiran Wu , Jiayu Huo , Gongyu Zhang , Zhen Yuan , Christos Bergeles , Rachel Sparks , Prokar Dasgupta , Alejandro Granados , Sebastien Ourselin

Cervical adenocarcinoma in situ (AIS) is a critical premalignant lesion whose accurate histopathological diagnosis is challenging. Early detection is essential to prevent progression to invasive cervical adenocarcinoma. In this study, we…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Gabriela Fernandes

Sepsis is a leading cause of death in the ICU. It is a disease requiring complex interventions in a short period of time, but its optimal treatment strategy remains uncertain. Evidence suggests that the practices of currently used treatment…

Machine Learning · Computer Science 2022-07-15 Zeyu Wang , Huiying Zhao , Peng Ren , Yuxi Zhou , Ming Sheng

The overexpression of human epidermal growth factor receptor 2 (HER2) has been established as a therapeutic target in multiple types of cancers, such as breast and gastric cancers. Immunohistochemistry (IHC) is employed as a basic HER2 test…

Image and Video Processing · Electrical Eng. & Systems 2020-09-16 Jun Zhang , Kuan Tian , Pei Dong , Haocheng Shen , Kezhou Yan , Jianhua Yao , Junzhou Huang , Xiao Han

The use of AI systems in healthcare for the early screening of diseases is of great clinical importance. Deep learning has shown great promise in medical imaging, but the reliability and trustworthiness of AI systems limit their deployment…

Image and Video Processing · Electrical Eng. & Systems 2023-05-17 Ke Zou , Zhihao Chen , Xuedong Yuan , Xiaojing Shen , Meng Wang , Huazhu Fu

Chronic obstructive pulmonary disease (COPD) represents a significant global health burden, where precise severity assessment is particularly critical for effective clinical management in intensive care unit (ICU) settings. This study…

Machine Learning · Computer Science 2025-04-29 Akram Shojaei , Mehdi Delrobaei

Artificial Intelligence (AI) can potentially support histopathologists in the diagnosis of a broad spectrum of cancer types. In colorectal cancer (CRC), AI can alleviate the laborious task of characterization and reporting on resected…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 John-Melle Bokhorst , Iris D. Nagtegaal , Filippo Fraggetta , Simona Vatrano , Wilma Mesker , Michael Vieth , Jeroen van der Laak , Francesco Ciompi

Celiac Disease (CD) is a chronic autoimmune disease that affects the small intestine in genetically predisposed children and adults. Gluten exposure triggers an inflammatory cascade which leads to compromised intestinal barrier function. If…

Image and Video Processing · Electrical Eng. & Systems 2019-10-09 Rasoul Sali , Lubaina Ehsan , Kamran Kowsari , Marium Khan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

Traditional methods for assessing illness severity and predicting in-hospital mortality among critically ill patients require time-consuming, error-prone calculations using static variable thresholds. These methods do not capitalize on the…

Machine Learning · Computer Science 2019-02-14 Benjamin Shickel , Tyler J. Loftus , Lasith Adhikari , Tezcan Ozrazgat-Baslanti , Azra Bihorac , Parisa Rashidi

This study presents an integrated deep learning model for automatic detection and classification of Gastrointestinal bleeding in the frames extracted from Wireless Capsule Endoscopy (WCE) videos. The dataset has been released as part of…

Image and Video Processing · Electrical Eng. & Systems 2024-12-09 Ayushman Singh , Sharad Prakash , Aniket Das , Nidhi Kushwaha

In critical care, intensivists are required to continuously monitor high dimensional vital signs and lab measurements to detect and diagnose acute patient conditions. This has always been a challenging task. In this study, we propose a…

Machine Learning · Computer Science 2019-01-15 Ziyuan Pan , Hao Du , Kee Yuan Ngiam , Fei Wang , Ping Shum , Mengling Feng

Ability to quantify and predict progression of a disease is fundamental for selecting an appropriate treatment. Many clinical metrics cannot be acquired frequently either because of their cost (e.g. MRI, gait analysis) or because they are…

Machine Learning · Statistics 2019-05-28 Guanyang Wang , Yumeng Zhang , Yong Deng , Xuxin Huang , Łukasz Kidziński

In the last two decades Computer Aided Diagnostics (CAD) systems were developed to help radiologists analyze screening mammograms. The benefits of current CAD technologies appear to be contradictory and they should be improved to be…

Computer Vision and Pattern Recognition · Computer Science 2017-11-10 Dezső Ribli , Anna Horváth , Zsuzsa Unger , Péter Pollner , István Csabai