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This study addresses critical gaps in automated lymphoma segmentation from PET/CT images, focusing on issues often overlooked in existing literature. While deep learning has been applied for lymphoma lesion segmentation, few studies…

This study integrates PET metabolic information with CT anatomical structures to establish a 3D multimodal segmentation dataset for lymphoma based on whole-body FDG PET/CT examinations, which bridges the gap of the lack of standardised…

Image and Video Processing · Electrical Eng. & Systems 2025-12-08 Jiajun Ding , Beiyao Zhu , Xiaosheng Liu , Lishen Zhang , Zhao Liu

Sequential whole-body 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) scans are regarded as the imaging modality of choice for the assessment of treatment response in the lymphomas because they detect treatment response when…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Kai-Chieh Liang , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…

Segmentation of lymphoma lesions is challenging due to their varied sizes and locations in whole-body PET scans. This work presents a fully-automated segmentation technique using a multi-center dataset of diffuse large B-cell lymphoma…

Automated slice classification is clinically relevant since it can be incorporated into medical image segmentation workflows as a preprocessing step that would flag slices with a higher probability of containing tumors, thereby directing…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Shadab Ahamed , Yixi Xu , Ingrid Bloise , Joo H. O , Carlos F. Uribe , Rahul Dodhia , Juan L. Ferres , Arman Rahmim

PET and CT are two modalities widely used in medical image analysis. Accurately detecting and segmenting lymphomas from these two imaging modalities are critical tasks for cancer staging and radiotherapy planning. However, this task is…

Image and Video Processing · Electrical Eng. & Systems 2021-04-28 Ling Huang , Su Ruan , Pierre Decazes , Thierry Denoeux

Automatic lymph node (LN) segmentation and detection for cancer staging are critical. In clinical practice, computed tomography (CT) and positron emission tomography (PET) imaging detect abnormal LNs. Despite its low contrast and variety in…

Image and Video Processing · Electrical Eng. & Systems 2022-12-23 Al-Akhir Nayan , Boonserm Kijsirikul , Yuji Iwahori

Lymphoma detection and segmentation from whole-body Positron Emission Tomography/Computed Tomography (PET/CT) volumes are crucial for surgical indication and radiotherapy. Designing automatic segmentation methods capable of effectively…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 Ling Huang , Thierry Denoeux , David Tonnelet , Pierre Decazes , Su Ruan

Purpose: The main purpose of this study was to assess the reliability of shape and heterogeneity features in both Positron Emission Tomography (PET) and low-dose Computed Tomography (CT) components of PET/CT. A secondary objective was to…

Computer Vision and Pattern Recognition · Computer Science 2016-10-06 Marie-Charlotte Desseroit , Florent Tixier , Wolfgang Weber , Barry A Siegel , Catherine Cheze Le Rest , Dimitris Visvikis , Mathieu Hatt

The escalating global cancer burden underscores the critical need for precise diagnostic tools in oncology. This research employs deep learning to enhance lesion segmentation in PET/CT imaging, utilizing a dataset of 900 whole-body…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Jiayi Liu , Qiaoyi Xue , Youdan Feng , Tianming Xu , Kaixin Shen , Chuyun Shen , Yuhang Shi

The objective of this study was to develop a PET tumor-segmentation framework that addresses the challenges of limited spatial resolution, high image noise, and lack of clinical training data with ground-truth tumor boundaries in PET…

Accurate liver and tumor segmentation on abdominal CT images is critical for reliable diagnosis and treatment planning, but remains challenging due to complex anatomical structures, variability in tumor appearance, and limited annotated…

Image and Video Processing · Electrical Eng. & Systems 2026-01-21 Arefin Ittesafun Abian , Ripon Kumar Debnath , Md. Abdur Rahman , Mohaimenul Azam Khan Raiaan , Md Rafiqul Islam , Asif Karim , Reem E. Mohamed , Sami Azam

Fluorodeoxyglucose (FDG) positron emission tomography (PET) combined with computed tomography (CT) is considered the primary solution for detecting some cancers, such as lung cancer and melanoma. Automatic segmentation of tumors in PET/CT…

Image and Video Processing · Electrical Eng. & Systems 2023-09-15 Linghan Cai , Jianhao Huang , Zihang Zhu , Jinpeng Lu , Yongbing Zhang

Accurate detection and segmentation of diffuse large B-cell lymphoma (DLBCL) from PET images has important implications for estimation of total metabolic tumor volume, radiomics analysis, surgical intervention and radiotherapy. Manual…

Image and Video Processing · Electrical Eng. & Systems 2024-03-13 Shadab Ahamed , Natalia Dubljevic , Ingrid Bloise , Claire Gowdy , Patrick Martineau , Don Wilson , Carlos F. Uribe , Arman Rahmim , Fereshteh Yousefirizi

Background: A crucial initial processing step for quantitative PET/CT analysis is the segmentation of tumor lesions enabling accurate feature ex-traction, tumor characterization, oncologic staging, and image-based therapy response…

Image and Video Processing · Electrical Eng. & Systems 2022-10-18 Ludovic Sibille , Xinrui Zhan , Lei Xiang

Uterine leiomyosarcoma (LMS) is a rare but aggressive malignancy. On imaging, it is difficult to differentiate LMS from, for example, degenerated leiomyoma (LM), a prevalent but benign condition. We curated a data set of 115 axial…

An automatic segmentation algorithm for delineation of the gross tumour volume and pathologic lymph nodes of head and neck cancers in PET/CT images is described. The proposed algorithm is based on a convolutional neural network using the…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Yngve Mardal Moe , Aurora Rosvoll Groendahl , Martine Mulstad , Oliver Tomic , Ulf Indahl , Einar Dale , Eirik Malinen , Cecilia Marie Futsaether

Lymph node (LN) metastasis status is one of the most critical prognostic and cancer staging factors for patients with resectable pancreatic ductal adenocarcinoma (PDAC), or in general, for any types of solid malignant tumors. Preoperative…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Zhilin Zheng , Xu Fang , Jiawen Yao , Mengmeng Zhu , Le Lu , Lingyun Huang , Jing Xiao , Yu Shi , Hong Lu , Jianping Lu , Ling Zhang , Chengwei Shao , Yun Bian

Numerous oncology indications have extensively quantified metabolically active tumors using positron emission tomography (PET) and computed tomography (CT). F-fluorodeoxyglucose-positron emission tomography (FDG-PET) is frequently utilized…

Image and Video Processing · Electrical Eng. & Systems 2022-10-17 Sepideh Amiri , Bulat Ibragimov
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