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It is crucial to design Phase II cancer clinical trials that balance the efficiency of treatment selection with clinical practicality. Sargent and Goldberg proposed a frequentist design that allow decision-making even when the primary…

Methodology · Statistics 2025-05-15 Moka Komaki , Satoru Shinoda , Haiyan Zheng , Kouji Yamamoto

The efficient importance sampling (EIS) method is a general principle for the numerical evaluation of high-dimensional integrals that uses the sequential structure of target integrands to build variance minimising importance samplers.…

Computation · Statistics 2013-09-27 Marcel Scharth , Robert Kohn

Scientific claims gain credibility by replicability, especially if replication under different circumstances and varying designs yields equivalent results. Aggregating results over multiple studies is, however, not straightforward, and when…

Methodology · Statistics 2023-12-27 Thom Benjamin Volker , Irene Klugkist

We propose a Bayesian evidence-based inference framework based on relative belief ratios and apply it to discriminating between one and two incoherent optical point sources using spatial-mode demultiplexing (SPADE). Unlike the Helstrom…

Pseudo-Labeling is a simple and effective approach to semi-supervised learning. It requires criteria that guide the selection of pseudo-labeled data. The latter have been shown to crucially affect pseudo-labeling's generalization…

Machine Learning · Computer Science 2023-09-27 Julian Rodemann

A prediction interval covers a future observation from a random process in repeated sampling, and is typically constructed by identifying a pivotal quantity that is also an ancillary statistic. Analogously, a tolerance interval covers a…

Methodology · Statistics 2022-01-19 Geoffrey S Johnson

Probability proportional to size (PPS) sampling schemes with a target sample size aim to produce a sample comprising a specified number $n$ of items while ensuring that each item in the population appears in the sample with a probability…

Methodology · Statistics 2024-11-14 Brian Hentschel , Peter J. Haas , Yuanyuan Tian

Many Bayesian inference problems involve high dimensional models for which only a subset of the model variables are of actual interest. All other variables are just nuisance parameters that one would ideally like to integrate out…

Computation · Statistics 2025-08-13 Fabián González , Víctor Elvira , Joaquín Miguez

Replication studies are increasingly conducted but there is no established statistical criterion for replication success. We propose a novel approach combining reverse-Bayes analysis with Bayesian hypothesis testing: a sceptical prior is…

Methodology · Statistics 2022-12-15 Samuel Pawel , Leonhard Held

In modern data analysis, nonparametric measures of discrepancies between random variables are particularly important. The subject is well-studied in the frequentist literature, while the development in the Bayesian setting is limited where…

Methodology · Statistics 2022-01-25 Qinyi Zhang , Veit Wild , Sarah Filippi , Seth Flaxman , Dino Sejdinovic

Simulation offers a simple and flexible way to estimate the power of a clinical trial when analytic formulae are not available. The computational burden of using simulation has, however, restricted its application to only the simplest of…

We develop scalable methods for producing conformal Bayesian predictive intervals with finite sample calibration guarantees. Bayesian posterior predictive distributions, $p(y \mid x)$, characterize subjective beliefs on outcomes of…

Methodology · Statistics 2021-06-15 Edwin Fong , Chris Holmes

Bayesian inference involves two main computational challenges. First, in estimating the parameters of some model for the data, the posterior distribution may well be highly multi-modal: a regime in which the convergence to stationarity of…

Instrumentation and Methods for Astrophysics · Physics 2019-12-10 F. Feroz , M. P. Hobson , E. Cameron , A. N. Pettitt

We propose a new empirical Bayes approach for inference in the $p \gg n$ normal linear model. The novelty is the use of data in the prior in two ways, for centering and regularization. Under suitable sparsity assumptions, we establish a…

Statistics Theory · Mathematics 2018-12-06 Ryan Martin , Raymond Mess , Stephen G. Walker

The Bayes Error Rate (BER) is the fundamental limit on the achievable generalizable classification accuracy of any machine learning model due to inherent uncertainty within the data. BER estimators offer insight into the difficulty of any…

Machine Learning · Computer Science 2025-09-24 Lesley Wheat , Martin v. Mohrenschildt , Saeid Habibi

In the management of most chronic conditions characterized by the lack of universally effective treatments, adaptive treatment strategies (ATSs) have been growing in popularity as they offer a more individualized approach, and sequential…

Methodology · Statistics 2021-08-03 Armando Turchetta , Erica E. M. Moodie , David A. Stephens , Sylvie D. Lambert

Machine learning (ML) methods are being increasingly used across various domains of medicine research. However, despite advancements in the use of ML in medicine, clear and definitive guidelines for determining sample sizes in medical ML…

Methodology · Statistics 2025-03-11 Wan Nor Arifin , Najib Majdi Yaacob

Bayesian analysis is increasingly popular for use in social science and other application areas where the data are observations from an informative sample. An informative sampling design leads to inclusion probabilities that are correlated…

Statistics Theory · Mathematics 2016-06-07 Terrance D. Savitsky , Daniell Toth

How to sample high quality negative instances from unlabeled data, i.e., negative sampling, is important for training implicit collaborative filtering and contrastive learning models. Although previous studies have proposed some approaches…

Information Retrieval · Computer Science 2022-07-12 Bin Liu , Bang Wang

In the class of normal regression models with a finite number of regressors, and for a wide class of prior distributions, a Bayesian model selection procedure based on the Bayes factor is consistent [Casella and Moreno J. Amer. Statist.…

Statistics Theory · Mathematics 2010-10-20 Elías Moreno , F. Javier Girón , George Casella
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