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Longitudinal analysis in medical imaging is crucial to investigate the progressive changes in anatomical structures or disease progression over time. In recent years, a novel class of algorithms has emerged with the goal of learning disease…

Longitudinal imaging is able to capture both static anatomical structures and dynamic changes in disease progression toward earlier and better patient-specific pathology management. However, conventional approaches rarely take advantage of…

Disease progression modeling aims to characterize and predict how a patient's disease complications worsen over time based on longitudinal electronic health records (EHRs). For diseases such as type 2 diabetes, accurate progression modeling…

Artificial Intelligence · Computer Science 2026-03-31 Tingsong Xiao , Yao An Lee , Zelin Xu , Yupu Zhang , Zibo Liu , Yu Huang , Jiang Bian , Jingchuan Guo , Zhe Jiang

Pre-training strategies based on self-supervised learning (SSL) have proven to be effective pretext tasks for many downstream tasks in computer vision. Due to the significant disparity between medical and natural images, the application of…

Longitudinal imaging is able to capture both static anatomical structures and dynamic changes in disease progression towards earlier and better patient-specific pathology management. However, conventional approaches for detecting diabetic…

Computer Vision and Pattern Recognition · Computer Science 2024-03-26 Rachid Zeghlache , Pierre-Henri Conze , Mostafa El Habib Daho , Ramin Tadayoni , Pascal Massin , Béatrice Cochener , Gwenolé Quellec , Mathieu Lamard

Robust forecasting of the future anatomical changes inflicted by an ongoing disease is an extremely challenging task that is out of grasp even for experienced healthcare professionals. Such a capability, however, is of great importance…

Computer Vision and Pattern Recognition · Computer Science 2022-11-09 Dmitrii Lachinov , Arunava Chakravarty , Christoph Grechenig , Ursula Schmidt-Erfurth , Hrvoje Bogunovic

Neural ordinary differential equations (NODE) have been proposed as a continuous depth generalization to popular deep learning models such as Residual networks (ResNets). They provide parameter efficiency and automate the model selection…

Machine Learning · Computer Science 2021-12-24 Srinivas Anumasa , P. K. Srijith

Alzheimer's Dementia (AD) represents one of the most pressing challenges in the field of neurodegenerative disorders, with its progression analysis being crucial for understanding disease dynamics and developing targeted interventions.…

Computer Vision and Pattern Recognition · Computer Science 2024-07-10 Jacob Thrasher , Alina Devkota , Ahmed Tafti , Binod Bhattarai , Prashnna Gyawali

Neural ordinary differential equations (NODE) have been proposed as a continuous depth generalization to popular deep learning models such as Residual networks (ResNets). They provide parameter efficiency and automate the model selection…

Machine Learning · Computer Science 2021-12-24 Srinivas Anumasa , P. K. Srijith

Longitudinal imaging is capable of capturing the static ana\-to\-mi\-cal structures and the dynamic changes of the morphology resulting from aging or disease progression. Self-supervised learning allows to learn new representation from…

Image and Video Processing · Electrical Eng. & Systems 2019-10-25 Antoine Rivail , Ursula Schmidt-Erfurth , Wolf-Dieter Vogl , Sebastian M. Waldstein , Sophie Riedl , Christoph Grechenig , Zhichao Wu , Hrvoje Bogunović

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Longitudinal neuroimaging is essential for modeling disease progression in Alzheimer's disease (AD), yet irregular sampling and missing visits pose substantial challenges for learning reliable temporal representations. To address this…

Machine Learning · Computer Science 2026-03-24 Ruiying Chen , Yutong Wang , Houliang Zhou , Wei Liang , Yong Chen , Lifang He

The advancement of human healthspan and bioengineering relies heavily on predicting the behavior of complex biological systems. While high-throughput multiomics data is becoming increasingly abundant, converting this data into actionable…

Machine Learning · Computer Science 2025-12-10 Udesh Habaraduwa , Andrei Lixandru

With widespread adoption of electronic health records, there is an increased emphasis for predictive models that can effectively deal with clinical time-series data. Powered by Recurrent Neural Network (RNN) architectures with Long…

Machine Learning · Statistics 2018-07-17 Huan Song , Deepta Rajan , Jayaraman J. Thiagarajan , Andreas Spanias

Generating realistic images to accurately predict changes in the structure of brain MRI is a crucial tool for clinicians. Such applications help assess patients' outcomes and analyze how diseases progress at the individual level. However,…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Mattia Litrico , Francesco Guarnera , Valerio Giuffirda , Daniele Ravì , Sebastiano Battiato

Early diagnosis of disease can lead to improved health outcomes, including higher survival rates and lower treatment costs. With the massive amount of information available in electronic health records (EHRs), there is great potential to…

Machine Learning · Computer Science 2022-08-02 Asem Alaa , Erik Mayer , Mauricio Barahona

Neural Ordinary Differential Equations (NODEs) have proven to be a powerful modeling tool for approximating (interpolation) and forecasting (extrapolation) irregularly sampled time series data. However, their performance degrades…

Machine Learning · Computer Science 2020-04-29 Hammad A. Ayyubi , Yi Yao , Ajay Divakaran

Identifying objective neuroimaging biomarkers to forecast Alzheimer's disease (AD) progression is crucial for timely intervention. However, this task remains challenging due to the complex dysfunctions in the spatio-temporal characteristics…

Diabetes remains a significant health challenge globally, contributing to severe complications like kidney disease, vision loss, and heart issues. The application of machine learning (ML) in healthcare enables efficient and accurate disease…

Machine Learning · Computer Science 2025-05-13 Mahade Hasan , Farhana Yasmin

Self-supervised learning (SSL) has emerged as a powerful technique for improving the efficiency and effectiveness of deep learning models. Contrastive methods are a prominent family of SSL that extract similar representations of two…

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