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The predictive quality of machine learning models is typically measured in terms of their (approximate) expected prediction error or the so-called Area Under the Curve (AUC) for a particular data distribution. However, when the models are…

Machine Learning · Computer Science 2018-02-08 Hiva Ghanbari , Katya Scheinberg

ROC analyses are considered under a variety of assumptions concerning the distributions of a measurement $X$ in two populations. These include the binormal model as well as nonparametric models where little is assumed about the form of…

Applications · Statistics 2021-03-02 Luai Al Labadi , Michael Evans , Qiaoyu Liang

Background: Medical decision-making impacts both individual and public health. Clinical scores are commonly used among a wide variety of decision-making models for determining the degree of disease deterioration at the bedside. AutoScore…

Time-dependent Receiver Operating Characteristics (ROC) analysis is a standard method to evaluate the discriminative performance of biomarkers or risk scores for time-to-event outcomes. Extensions of this useful method to left-truncated…

Methodology · Statistics 2025-09-09 Kendrick Li , Mithun Kumar Acharjee

With growing concerns regarding bias and discrimination in predictive models, the AI community has increasingly focused on assessing AI system trustworthiness. Conventionally, trustworthy AI literature relies on the probabilistic framework…

Machine Learning · Statistics 2024-01-05 Ritwik Vashistha , Arya Farahi

It is well-known that deep learning models are vulnerable to adversarial examples. Existing studies of adversarial training have made great progress against this challenge. As a typical trait, they often assume that the class distribution…

Machine Learning · Computer Science 2022-06-27 Wenzheng Hou , Qianqian Xu , Zhiyong Yang , Shilong Bao , Yuan He , Qingming Huang

In the machine learning culture, an independent test set is required for proper model verification. Failures in model verification, including test set omission and test set leakage, make it impossible to know whether or not a trained model…

Genomics · Quantitative Biology 2021-07-09 Thomas P. Quinn

The Partial Area Under the ROC Curve (PAUC), typically including One-way Partial AUC (OPAUC) and Two-way Partial AUC (TPAUC), measures the average performance of a binary classifier within a specific false positive rate and/or true positive…

Machine Learning · Computer Science 2022-10-12 Huiyang Shao , Qianqian Xu , Zhiyong Yang , Shilong Bao , Qingming Huang

The interpretation of chest radiographs is an essential task for the detection of thoracic diseases and abnormalities. However, it is a challenging problem with high inter-rater variability and inherent ambiguity due to inconclusive…

Computer Vision and Pattern Recognition · Computer Science 2019-06-20 Florin C. Ghesu , Bogdan Georgescu , Eli Gibson , Sebastian Guendel , Mannudeep K. Kalra , Ramandeep Singh , Subba R. Digumarthy , Sasa Grbic , Dorin Comaniciu

The receiver operating characteristic (ROC) curve is a very useful tool for analyzing the diagnostic/classification power of instruments/classification schemes as long as a binary-scale gold standard is available. When the gold standard is…

Methodology · Statistics 2011-05-10 Zhanfeng Wang , Yuan-chin Ivan Chang

Emergence of artificial intelligence techniques in biomedical applications urges the researchers to pay more attention on the uncertainty quantification (UQ) in machine-assisted medical decision making. For classification tasks, prior…

Machine Learning · Computer Science 2019-09-17 Xiaoyang Huang , Jiancheng Yang , Linguo Li , Haoran Deng , Bingbing Ni , Yi Xu

Machine learning models deployed in real-world applications are often evaluated with precision-based metrics such as F1-score or AUC-PR (Area Under the Curve of Precision Recall). Heavily dependent on the class prior, such metrics make it…

Machine Learning · Computer Science 2020-04-29 Wissam Siblini , Jordan Fréry , Liyun He-Guelton , Frédéric Oblé , Yi-Qing Wang

Machine learning (ML) is increasingly employed in real-world applications like medicine or economics, thus, potentially affecting large populations. However, ML models often do not perform homogeneously, leading to underperformance or,…

Machine Learning · Computer Science 2025-08-28 Tom Siegl , Kutalmış Coşkun , Bjarne C. Hiller , Amin Mirzaei , Florian Lemmerich , Martin Becker

Context: There is considerable diversity in the range and design of computational experiments to assess classifiers for software defect prediction. This is particularly so, regarding the choice of classifier performance metrics.…

Software Engineering · Computer Science 2020-03-04 Jingxiu Yao , Martin Shepperd

Data and algorithms are essential and complementary parts of a large-scale decision-making process. However, their injudicious use can lead to unforeseen consequences, as has been observed by researchers and activists alike in the recent…

Machine Learning · Computer Science 2022-03-10 Shubham Singh , Bhuvni Shah , Chris Kanich , Ian A. Kash

In this extended abstract, we will present and discuss opportunities and challenges brought about by a new deep learning method by AUC maximization (aka \underline{\bf D}eep \underline{\bf A}UC \underline{\bf M}aximization or {\bf DAM}) for…

Machine Learning · Computer Science 2021-11-05 Tianbao Yang

We aim to quantitatively measure the practical usability of medical image segmentation models: to what extent, how often, and on which samples a model's predictions can be used/trusted. We first propose a measure, Correctness-Confidence…

Image and Video Processing · Electrical Eng. & Systems 2022-07-04 Yizhe Zhang , Suraj Mishra , Peixian Liang , Hao Zheng , Danny Z. Chen

Several efforts have been done to bring ROC analysis beyond (binary) classification, especially in regression. However, the mapping and possibilities of these proposals do not correspond to what we expect from the analysis of operating…

Statistics Theory · Mathematics 2013-10-17 Jose Hernandez-Orallo

Deployed machine learning models should be updated to take advantage of a larger sample size to improve performance, as more data is gathered over time. Unfortunately, even when model updates improve aggregate metrics such as accuracy, they…

Machine Learning · Computer Science 2023-05-09 George Adam , Benjamin Haibe-Kains , Anna Goldenberg

Along with the increasing availability of health data has come the rise of data-driven models to inform decision-making and policy. These models have the potential to benefit both patients and health care providers but can also exacerbate…

Methodology · Statistics 2023-10-16 Solvejg Wastvedt , Jared Huling , Julian Wolfson