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Current 3D photoacoustic tomography (PAT) systems offer either high image quality or high frame rates but are not able to deliver high spatial and temporal resolution simultaneously, which limits their ability to image dynamic processes in…

Numerical Analysis · Mathematics 2016-12-21 Simon Arridge , Paul Beard , Marta Betcke , Ben Cox , Nam Huynh , Felix Lucka , Olumide Ogunlade , Edward Zhang

Photo-acoustic tomography (PAT) aims to leverage the photo-acoustic coupling between optical absorption of light sources and ultrasound (US) emission to obtain high contrast reconstructions of optical parameters with the high resolution of…

Analysis of PDEs · Mathematics 2016-09-21 Guillaume Bal , Amir Moradifam

Purpose: Photoacoustic tomography (PAT) is a novel imaging technique that can spatially resolve both morphological and functional tissue properties, such as the vessel topology and tissue oxygenation. While this capacity makes PAT a…

Photoacoustic tomography (PAT) is a rapidly-evolving medical imaging modality that combines optical absorption contrast with ultrasound imaging depth. One challenge in PAT is image reconstruction with inadequate acoustic signals due to…

Three-dimensional (3D) photoacoustic computed tomography (PACT) is a powerful noninvasive biomedical imaging modality that provides volumetric data for structural and functional assessment \textit{in vivo}. To maximize angular coverage and…

Medical Physics · Physics 2026-03-26 Wanqing Zhang , Hengyue Zhu , Yide Zhang

Photoacoustic tomography (PAT) combines the advantages of the spectroscopic optical absorption contrast and acoustic resolution with deep penetration, and becomes an important novel biomedical imaging technology for scientific research and…

Instrumentation and Detectors · Physics 2021-12-23 Daohuai Jiang , Yifei Xu , Hengrong Lan , Feng Gao , Fei Gao

The development of fast and accurate image reconstruction algorithms is a central aspect of computed tomography. In this paper, we investigate this issue for the sparse data problem in photoacoustic tomography (PAT). We develop a direct and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Stephan Antholzer , Markus Haltmeier , Johannes Schwab

Photoacoustic tomography (PAT) offers high optical contrast with acoustic imaging depth, making it essential for biomedical applications. While many all-optical systems have been developed to address limitations of ultrasound transducers,…

Optics · Physics 2024-10-11 Taeil Yoon , Hakseok Ko , Jeongmyo Im , Euiheon Chung , Wonshik Choi , Byeong Ha Lee

As an emerging medical diagnostic technology, photoacoustic imaging has been implemented for both preclinical and clinical applications. For clinical convenience, a handheld free scan photoacoustic tomography (PAT) system providing 3D…

Medical Physics · Physics 2022-03-18 Daohuai Jiang , Hongbo Chen , Yuting Shen , Yifan Zhang , Feng Gao , Rui Zheng , Fei Gao

Photoacoustic tomography is a hybrid biomedical technology, which combines the advantages of acoustic and optical imaging. However, for the conventional image reconstruction method, the image quality is affected obviously by artifacts under…

Image and Video Processing · Electrical Eng. & Systems 2024-06-26 Bowei Yao , Yi Zeng , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Yuyao Zhang , Jingyi Yu , Xiran Cai

Photoacoustic tomography (PAT) is a nonionizing imaging modality capable of acquiring high contrast and resolution images of optical absorption at depths greater than traditional optical imaging techniques. Practical considerations with…

Image and Video Processing · Electrical Eng. & Systems 2020-06-30 Steven Guan , Amir A. Khan , Siddhartha Sikdar , Parag V. Chitnis

A crucial limitation of current high-resolution 3D photoacoustic tomography (PAT) devices that employ sequential scanning is their long acquisition time. In previous work, we demonstrated how to use compressed sensing techniques to improve…

Numerical Analysis · Mathematics 2020-09-07 Felix Lucka , Nam Huynh , Marta Betcke , Edward Zhang , Paul Beard , Ben Cox , Simon Arridge

Photoacoustic Microscopy (PAM) images integrating the advantages of optical contrast and acoustic resolution have been widely used in brain studies. However, there exists a trade-off between scanning speed and image resolution. Compared…

Image and Video Processing · Electrical Eng. & Systems 2025-03-06 Kai Pan , Linyang Li , Li Lin , Pujin Cheng , Junyan Lyu , Lei Xi , Xiaoyin Tang

Photoacoustic tomography (PAT) is a newly developed medical imaging modality, which combines the advantages of pure optical imaging and ultrasound imaging, owning both high optical contrast and deep penetration depth. Very recently, PAT is…

Medical Physics · Physics 2021-09-21 Tengbo Lyu , Jiadong Zhang , Zijian Gao , Changchun Yang , Feng Gao , Fei Gao

Photoacoustic tomography (PAT) is an emerging and non-invasive hybrid imaging modality for visualizing light absorbing structures in biological tissue. The recently invented PAT systems using arrays of 64 parallel integrating line detectors…

Numerical Analysis · Mathematics 2018-08-31 Johannes Schwab , Stephan Antholzer , Robert Nuster , Markus Haltmeier

Photoacoustic tomography (PAT) enables non-invasive cross-sectional imaging of biological tissues, but it fails to map the spatial variation of speed-of-sound (SOS) within tissues. While SOS is intimately linked to density and elastic…

Medical Physics · Physics 2024-08-27 Yang Wang , Danni Wang , Liting Zhong , Yi Zhou , Qing Wang , Wufan Chen , Li Qi

Photoacoustic tomography (PAT) is a medical imaging modality that can provide high-resolution tissue images based on the optical absorption. Classical reconstruction methods for quantifying the absorption coefficients rely on sufficient…

Image and Video Processing · Electrical Eng. & Systems 2026-04-24 Anssi Manninen , Janek Gröhl , Felix Lucka , Andreas Hauptmann

Photoacoustic imaging can achieve high-resolution three-dimensional visualization of optical absorbers at penetration depths ~ 1 cm in biological tissues by detecting optically-induced high ultrasound frequencies. Tomographic acquisition…

Optics · Physics 2015-05-15 Jérôme Gateau , Marc Gesnik , Jean-Marie Chassot , Emmanuel Bossy

Photoacoustic tomography (PAT) is a non-invasive imaging modality that requires recovering the initial data of the wave equation from certain measurements of the solution outside the object. In the standard PAT measurement setup, the used…

Analysis of PDEs · Mathematics 2021-12-07 Linh V. Nguyen , Markus Haltmeier , Richard Kowar , Ngoc Do

Imaging the human body's morphological and angiographic information is essential for diagnosing, monitoring, and treating medical conditions. Ultrasonography performs the morphological assessment of the soft tissue based on acoustic…

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