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Large Language Models (LLMs) have demonstrated substantial progress in biomedical and clinical applications, motivating rigorous evaluation of their ability to answer nuanced, evidence-based questions. We curate a multi-source benchmark…

Computation and Language · Computer Science 2025-09-16 Can Wang , Yiqun Chen

In support of open and reproducible research, there has been a rapidly increasing number of datasets made available for research. As the availability of datasets increases, it becomes more important to have quality metadata for discovering…

Computation and Language · Computer Science 2023-10-18 Shiwei Zhang , Mingfang Wu , Xiuzhen Zhang

Large language models (LLMs) can simulate clinical reasoning based on natural language prompts, but their utility in ophthalmology is largely unexplored. This study evaluated GPT-4's ability to interpret structured textual descriptions of…

Computation and Language · Computer Science 2025-07-03 Cindy Lie Tabuse , David Restepo , Carolina Gracitelli , Fernando Korn Malerbi , Caio Regatieri , Luis Filipe Nakayama

The process of matching patients with suitable clinical trials is essential for advancing medical research and providing optimal care. However, current approaches face challenges such as data standardization, ethical considerations, and a…

Computation and Language · Computer Science 2023-08-08 Jiayi Yuan , Ruixiang Tang , Xiaoqian Jiang , Xia Hu

Robots are increasingly common in industry and daily life, such as in nursing homes where they can assist staff. A key challenge is developing intuitive interfaces for easy communication. The use of Large Language Models (LLMs) like GPT-4…

Robotics · Computer Science 2024-08-01 Stanislau Stankevich , Wojciech Dudek

General purpose Large Language Models (LLM) such as the Generative Pretrained Transformer (GPT) and Large Language Model Meta AI (LLaMA) have attracted much attention in recent years. There is strong evidence that these models can perform…

Computation and Language · Computer Science 2024-04-25 Hossein Salami , Brandye Smith-Goettler , Vijay Yadav

Large language models (LLMs) have demonstrated remarkable capabilities in natural language understanding and generation across various domains, including medicine. We present a comprehensive evaluation of GPT-4, a state-of-the-art LLM, on…

Computation and Language · Computer Science 2023-04-13 Harsha Nori , Nicholas King , Scott Mayer McKinney , Dean Carignan , Eric Horvitz

Large language models (LLMs) have made significant progress in various domains, including healthcare. However, the specialized nature of clinical language understanding tasks presents unique challenges and limitations that warrant further…

Computation and Language · Computer Science 2023-08-01 Yuqing Wang , Yun Zhao , Linda Petzold

The exponential growth of unstructured text data presents a fundamental challenge in modern data management and information retrieval. While Large Language Models (LLMs) have shown remarkable capabilities in natural language processing,…

Artificial Intelligence · Computer Science 2025-05-06 William Brach , Kristián Košťál , Michal Ries

Large Language Models (LLMs), typified by OpenAI's GPT, have marked a significant advancement in artificial intelligence. Trained on vast amounts of text data, LLMs are capable of understanding and generating human-like text across a…

Artificial Intelligence · Computer Science 2024-10-29 Haochen Zhang , Yuyang Dong , Chuan Xiao , Masafumi Oyamada

This study investigates the automation of meta-analysis in scientific documents using large language models (LLMs). Meta-analysis is a robust statistical method that synthesizes the findings of multiple studies support articles to provide a…

Computation and Language · Computer Science 2024-11-19 Jawad Ibn Ahad , Rafeed Mohammad Sultan , Abraham Kaikobad , Fuad Rahman , Mohammad Ruhul Amin , Nabeel Mohammed , Shafin Rahman

Artificial intelligence (AI) is widely deployed to solve problems related to marketing attribution and budget optimization. However, AI models can be quite complex, and it can be difficult to understand model workings and insights without…

Computation and Language · Computer Science 2024-04-23 Yilin Gao , Sai Kumar Arava , Yancheng Li , James W. Snyder

This paper describes a rapid feasibility study of using GPT-4, a large language model (LLM), to (semi)automate data extraction in systematic reviews. Despite the recent surge of interest in LLMs there is still a lack of understanding of how…

Computation and Language · Computer Science 2025-02-14 Lena Schmidt , Kaitlyn Hair , Sergio Graziosi , Fiona Campbell , Claudia Kapp , Alireza Khanteymoori , Dawn Craig , Mark Engelbert , James Thomas

Although supervised machine learning is popular for information extraction from clinical notes, creating large annotated datasets requires extensive domain expertise and is time-consuming. Meanwhile, large language models (LLMs) have…

Computation and Language · Computer Science 2024-01-26 Madhumita Sushil , Travis Zack , Divneet Mandair , Zhiwei Zheng , Ahmed Wali , Yan-Ning Yu , Yuwei Quan , Atul J. Butte

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

Scientific metadata often suffer from incompleteness, inconsistency, and formatting errors, which hinder effective discovery and reuse of the associated datasets. We present a method that combines GPT-4 with structured metadata templates…

Information Retrieval · Computer Science 2025-06-10 Sowmya S Sundaram , Rafael S. Gonçalves , Mark A Musen

Large language models (LLMs) are currently being used to answer medical questions across a variety of clinical domains. Recent top-performing commercial LLMs, in particular, are also capable of citing sources to support their responses. In…

Computation and Language · Computer Science 2024-02-06 Kevin Wu , Eric Wu , Ally Cassasola , Angela Zhang , Kevin Wei , Teresa Nguyen , Sith Riantawan , Patricia Shi Riantawan , Daniel E. Ho , James Zou

Data science plays a critical role in biomedical research, but it requires professionals with expertise in coding and medical data analysis. Large language models (LLMs) have shown great potential in supporting medical tasks and performing…

Artificial Intelligence · Computer Science 2025-04-10 Zifeng Wang , Benjamin Danek , Ziwei Yang , Zheng Chen , Jimeng Sun

Large Language Models (LLMs) have made remarkable advancements in the field of natural language processing. However, their increasing size poses challenges in terms of computational cost. On the other hand, Small Language Models (SLMs) are…

Computation and Language · Computer Science 2023-08-03 Zhen Guo , Peiqi Wang , Yanwei Wang , Shangdi Yu

Large Language Models (LLMs) are commonly pretrained on vast corpora of text without utilizing contextual metadata such as source, quality, or topic, leading to a context-free learning paradigm. While recent studies suggest that adding…

Computation and Language · Computer Science 2025-11-25 Dongyang Fan , Vinko Sabolčec , Martin Jaggi
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