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This work is concerned with uncertainty quantification problems for image reconstructions in quantitative photoacoustic imaging (PAT), a recent hybrid imaging modality that utilizes the photoacoustic effect to achieve high-resolution…
Photoacoustic tomography is a hybrid imaging technique that combines high optical tissue contrast with high ultrasound resolution. Direct reconstruction methods such as filtered backprojection, time reversal and least squares suffer from…
In high-performance computing (HPC) environments, particularly in synchrotron radiation facilities, vast amounts of X-ray images are generated. Processing large-scale X-ray Computed Tomography (X-CT) datasets presents significant…
The reduction of metal artifacts in computed tomography (CT) images, specifically for strong artifacts generated from multiple metal objects, is a challenging issue in medical imaging research. Although there have been some studies on…
X-ray luminescence is produced when contrast agents absorb energy from X-ray photons and release a portion of that energy by emitting photons in the visible and near-infrared range. X-ray luminescence computed tomography (XLCT) was…
Dark-field radiography is a novel X-ray imaging modality that enables complementary diagnostic information by visualizing the microstructural properties of lung tissue. Implemented via a Talbot-Lau interferometer integrated into a…
Intraocular foreign body removal demands millimeter-level precision in confined intraocular spaces, yet existing robotic systems predominantly rely on manual teleoperation with steep learning curves. To address the challenges of autonomous…
Ultrasound 3D compounding is important for volumetric reconstruction, but as of yet there is no consensus on best practices for compounding. Ultrasound images depend on probe direction and the path sound waves pass through, so when multiple…
Optical coherence tomography (OCT) is a noninvasive technology that enables real-time imaging of tissue microanatomies. The axial resolution of OCT is intrinsically constrained by the spectral bandwidth of the employed light source while…
The diagnosis and treatment of various diseases had been expedited with the help of medical imaging. Different medical imaging modalities, including X-ray, Computed Tomography (CT), Magnetic Resonance Imaging (MRI), Nuclear Imaging,…
Diffusion-weighted MRI is nowadays performed routinely due to its prognostic ability, yet the quality of the scans are often unsatisfactory which can subsequently hamper the clinical utility. To overcome the limitations, here we propose a…
During X-ray computed tomography (CT) scanning, metallic implants carrying with patients often lead to adverse artifacts in the captured CT images and then impair the clinical treatment. Against this metal artifact reduction (MAR) task, the…
The invention of X-ray interferometers has led to advanced phase-sensing devices that are invaluable in various applications. These include the precise measurement of universal constants, e.g. the Avogadro number, of lattice parameters of…
This paper considers the non-linear inverse problem of reconstructing an electric conductivity distribution from the interior power density in a bounded domain. Applications include the novel tomographic method known as acousto-electric…
A new method for reducing metal artifacts in X-ray computed tomography (CT) images is presented. It bases on the solution of a convex optimization problem with inequality constraints on the sinogram, and total variation regularization for…
We present a method we developed for the correction of the beam divergence in finite distance sources imaging through coded mask instruments. We discuss the defocusing artifacts induced by the finite distance showing two different…
Ultrasound computed tomography techniques have the potential to provide clinicians with 3D, quantitative and high-resolution information of both soft and hard tissues such as the breast or the adult human brain. Their practical application…
Noninvasive transcranial photoacoustic computed tomography (PACT) of the human brain, despite its clinical potential as a complementary technology to functional MRI, remains impeded by the acoustic distortion induced by the human skull. The…
X-ray dark-field imaging creates a representation of the sample where contrast is generated by subresolution features within the volume under inspection. These are detected by a local measurement of the radiation field's angular…
In nuclear arms control and disarmament processes, it is crucial to determine whether an object is a nuclear weapon or not without revealing sensitive information about it. At the MIT: Laboratory for Nuclear Security and Policy, such a…