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Dementia is a complex syndrome impacting cognitive and emotional functions, with Alzheimer's disease being the most common form. This study focuses on enhancing dementia prediction using machine learning (ML) techniques on patient health…

Artificial Intelligence · Computer Science 2026-01-13 Shafiul Ajam Opee , Nafiz Fahad , Anik Sen , Rasel Ahmed , Fariha Jahan , Md. Kishor Morol , Md Rashedul Islam

Alzheimer's disease is a degenerative brain disease. Being the primary cause of Dementia in adults and progressively destroys brain memory. Though Alzheimer's disease does not have a cure currently, diagnosing it at an earlier stage will…

Machine Learning · Computer Science 2023-02-17 Shrish Pellakur , Nelly Elsayed , Zag ElSayed , Murat Ozer

Risk prediction models using genetic data have seen increasing traction in genomics. However, most of the polygenic risk models were developed using data from participants with similar (mostly European) ancestry. This can lead to biases in…

Machine Learning · Computer Science 2022-05-11 Prashnna K Gyawali , Yann Le Guen , Xiaoxia Liu , Hua Tang , James Zou , Zihuai He

Ensembling a neural network is a widely recognized approach to enhance model performance, estimate uncertainty, and improve robustness in deep supervised learning. However, deep ensembles often come with high computational costs and memory…

Multi-modal learning is a fast growing area in artificial intelligence. It tries to help machines understand complex things by combining information from different sources, like images, text, and audio. By using the strengths of each…

Machine Learning · Computer Science 2025-12-22 Qihang Jin , Enze Ge , Yuhang Xie , Hongying Luo , Junhao Song , Ziqian Bi , Chia Xin Liang , Jibin Guan , Joe Yeong , Xinyuan Song , Junfeng Hao

Brain aging is a regional phenomenon, a facet that remains relatively under-explored within the realm of brain age prediction research using machine learning methods. Voxel-level predictions can provide localized brain age estimates that…

Computer Vision and Pattern Recognition · Computer Science 2024-04-26 Neha Gianchandani , Mahsa Dibaji , Johanna Ospel , Fernando Vega , Mariana Bento , M. Ethan MacDonald , Roberto Souza

Large-scale medical studies such as the UK Biobank examine thousands of volunteer participants with medical imaging techniques. Combined with the vast amount of collected metadata, anatomical information from these images has the potential…

Image and Video Processing · Electrical Eng. & Systems 2021-05-18 Taro Langner , Robin Strand , Håkan Ahlström , Joel Kullberg

Multivariate functional data present theoretical and practical complications which are not found in univariate functional data. One of these is a situation where the component functions of multivariate functional data are positive and are…

Methodology · Statistics 2023-03-09 Cody Carroll , Hans-Georg Müller

Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that…

Machine Learning · Statistics 2019-04-15 Takashi Matsubara , Tetsuo Tashiro , Kuniaki Uehara

A plethora of machine learning methods have been applied to imaging data, enabling the construction of clinically relevant imaging signatures of neurological and neuropsychiatric diseases. Oftentimes, such methods don't explicitly model the…

Machine Learning · Computer Science 2022-05-11 Zhijian Yang , Junhao Wen , Christos Davatzikos

Recent advancements in medicine have confirmed that brain disorders often comprise multiple subtypes of mechanisms, developmental trajectories, or severity levels. Such heterogeneity is often associated with demographic aspects (e.g., sex)…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Magdalini Paschali , Yu Hang Jiang , Spencer Siegel , Camila Gonzalez , Kilian M. Pohl , Akshay Chaudhari , Qingyu Zhao

Deep neural networks (DNNs) have made a revolution in numerous fields during the last decade. However, in tasks with high safety requirements, such as medical or autonomous driving applications, providing an assessment of the models…

Machine Learning · Computer Science 2020-11-20 Omer Achrack , Raizy Kellerman , Ouriel Barzilay

Learned representations in deep reinforcement learning (DRL) have to extract task-relevant information from complex observations, balancing between robustness to distraction and informativeness to the policy. Such stable and rich…

Machine Learning · Computer Science 2021-10-28 Mete Kemertas , Tristan Aumentado-Armstrong

Deep learning methods have recently made notable advances in the tasks of classification and representation learning. These tasks are important for brain imaging and neuroscience discovery, making the methods attractive for porting to a…

Neural and Evolutionary Computing · Computer Science 2014-02-20 Sergey M. Plis , Devon R. Hjelm , Ruslan Salakhutdinov , Vince D. Calhoun

Data on functional disability are of widespread policy interest in the United States, especially with respect to planning for Medicare and Social Security for a growing population of elderly adults. We consider an extract of functional…

Applications · Statistics 2009-09-29 Elena A. Erosheva , Stephen E. Fienberg , Cyrille Joutard

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

For mental disorders, patients' underlying mental states are non-observed latent constructs which have to be inferred from observed multi-domain measurements such as diagnostic symptoms and patient functioning scores. Additionally,…

Machine Learning · Computer Science 2020-11-03 Yuan Chen , Donglin Zeng , Tianchen Xu , Yuanjia Wang

Accurate diagnosis and prognosis of Alzheimer's disease are crucial to develop new therapies and reduce the associated costs. Recently, with the advances of convolutional neural networks, methods have been proposed to automate these two…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Deep learning models are rapidly gaining interest for real-world applications in behavioral health. An important gap in current literature is how well such models generalize over different populations. We study Natural Language Processing…

Computation and Language · Computer Science 2024-12-30 Tomek Rutowski , Elizabeth Shriberg , Amir Harati , Yang Lu , Ricardo Oliveira , Piotr Chlebek

Deep neural networks are increasingly being used for the analysis of medical images. However, most works neglect the uncertainty in the model's prediction. We propose an uncertainty-aware deep kernel learning model which permits the…

Machine Learning · Computer Science 2021-06-11 Zhiliang Wu , Yinchong Yang , Jindong Gu , Volker Tresp