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Intensive concerns about the biosafety of nanomaterials demand the systematic study of the mechanisms about their biological effects. Many biological effects can be attributed to the interaction of nanomaterials with protein and their…

Biological Physics · Physics 2016-01-20 Deyi An , Jiguo Su , Chunhua Li , Jingyuan Li

We implemented a nanoelectronic interface between graphene field effect transistors (FETs) and soluble proteins. This enables production of bioelectronic devices that combine functionalities of the biomolecular and inorganic components. The…

Mesoscale and Nanoscale Physics · Physics 2015-06-03 Ye Lu , Mitchell B. Lerner , Zhengqing John Qi , Joseph J. Mitala , Jong Hsien Lim , Bohdana M. Discher , A. T. Charlie Johnson

We have developed a novel, all-electronic biosensor for opioids that consists of an engineered mu opioid receptor protein, with high binding affinity for opioids, chemically bonded to a graphene field-effect transistor to read out ligand…

Infrared spectroscopy is the technique of choice for chemical identification of biomolecules through their vibrational fingerprints. However, infrared light interacts poorly with nanometric size molecules. Here, we exploit the unique…

This review provides a critical overview of current developments on nanoelectronic biochemical sensors based on graphene. Composed of a single layer of conjugated carbon atoms, graphene has outstanding high carrier mobility and low…

Materials Science · Physics 2020-12-14 Xiaoyan Zhang , Qiushi Jing , Shen Ao , Grégory F. Schneider , Dmitry Kireev , Zhengjun Zhang , Wangyang Fu

We present a method where a bioactive functional layer on an electrically conductive thin film with high sheet resistance can be effectively used for complementary electrochemical impedance spectroscopy biosensing. The functional layer's…

Materials Science · Physics 2025-04-04 Munis Khan , Ivan Mijakovic , Santosh Pandit , August Yurgens

The exceptional conducting nature of graphene makes it a viable candidate for enhancing the effectiveness of photocatalytic and biomedical nanomaterials. Herein, the immobilization of monodispersed silicon dioxide (SiO2) nanoparticles on…

Applied Physics · Physics 2017-08-23 Aqsa Arshad , Javed Iqbal , Qaisar Mansoor , Ishaq Ahmad

This work presents an innovative magnetoelastic (ME) biosensor using graphene functionalized with the SARS-CoV-2 N protein for antibody detection via magnetoelastic resonance. Graphene was chosen for its biocompatibility and high surface…

Biomedical and environmental testing currently require access to highly specialized facilities or extensive training. Current biochemical tests require complex reagents to achieve a simple human readable result such as a color change. This…

Interfacing artificial functional materials and living neuronal tissues is at the forefront of bio-nano-technology. Attempts have been so far based onto microscale processing of metals and inorganic semiconductors as electrodes or…

The difficulty in determining the mass of a sample increases as its size diminishes. At the nanoscale, there are no direct methods for resolving the mass of single molecules or nanoparticles and so more sophisticated approaches based on…

Materials Science · Physics 2015-06-03 Stas M. Avdoshenko , Claudia Gomes da Rocha , Gianaurelio Cuniberti

Graphene is of increasing interest for optoelectronic applications exploiting light detection, light emission and light modulation. Intrinsically light matter interaction in graphene is of a broadband type. However by integrating graphene…

Understanding the role of microscopic attributes in nanocomposites allows for a controlled and, therefore, acceleration in experimental system designs. In this work, we extracted the relevant parameters controlling the graphene oxide…

The scientific community has witnessed an exponential increase in the applications of graphene and graphene-based materials in a wide range of fields. For what concerns neuroscience, the interest raised by these materials is two-fold. On…

Using molecular dynamics simulations, we investigated an integrated bio-nano interface consisting of a \b{eta}-sheet protein stacked onto graphene. We found that the stacking assembly of the model protein on graphene could be controlled by…

Biological Physics · Physics 2014-12-17 Wenping Lv , Guiju Xu , Hongyan Zhang , Xin Li , Shengju Liu , Huan Niu , Dongsheng Xu , Renan Wu

The biofunctionalization of nanoelectromechanical structures is critical for the development of new classes of biosensors displaying improved performances and higher-level of integration. We propose a modified microcontact printing method…

Mesoscale and Nanoscale Physics · Physics 2015-06-04 Sven Salomon , Thierry Leichle , Denis Dezest , Florent Seichepine , Samuel Guillon , Christophe Thibault , Christophe Vieu , Liviu Nicu

Recent surveys have shown that the number of nanoparticle-based formulations actually used at the clinical level is significantly lower than expected a decade ago. One reason for this is that the nanoparticle physicochemical properties fall…

Nanoparticles coated with hydrophilic polymers often show a reduction in unspecific interactions with the biological environment, which improves their biocompatibility. The molecular determinants of this reduction are not very well…

Soft Condensed Matter · Physics 2018-10-30 Giovanni Settanni , Timo Schäfer , Christian Muhl , Matthias Barz , Friederike Schmid

Determining potential abilities of nanostructures to induce toxicity to biological molecules is still a convoluted challenge in the realm of nanomedicine. Based on the unprecedented achievements of twodimensional nanomaterials in nearly all…

Biological Physics · Physics 2021-06-09 Ashkan Shekaari , Mahmoud Jafari

In this paper, we study the morphologic interaction between graphene and Si nanowires on a SiO2 substrate, using molecular mechanics simulations. Two cases are considered: 1) a graphene nanoribbon intercalated by a single Si nanowire on a…

Materials Science · Physics 2011-11-21 Zhao Zhang , Teng Li
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