Related papers: Linguistic Changes in Spontaneous Speech for Detec…
Parkinson's Disease (PD) is characterized by disorders in motor function such as freezing of gait, rest tremor, rigidity, and slowed and hyposcaled movements. Medication with dopaminergic medication may alleviate those motor symptoms,…
Alzheimer's disease (AD) has become one of the most significant health challenges in an aging society. The use of spoken language-based AD detection methods has gained prevalence due to their scalability due to their scalability. Based on…
Dementia is a growing problem as our society ages, and detection methods are often invasive and expensive. Recent deep-learning techniques can offer a faster diagnosis and have shown promising results. However, they require large amounts of…
Background and objectives: Parkinson's disease is a neurological disorder that affects the motor system producing lack of coordination, resting tremor, and rigidity. Impairments in handwriting are among the main symptoms of the disease.…
Parkinsons disease (PD) is considered one of the most frequent neurological diseases in the world. There is a need to study the early and efficient biomarkers of Parkinsons, such as changes in structural disorders like DNA and chromatin,…
Alzheimer's disease (AD) stands as the predominant cause of dementia, characterized by a gradual decline in speech and language capabilities. Recent deep-learning advancements have facilitated automated AD detection through spontaneous…
Dementia is a group of irreversible, chronic, and progressive neurodegenerative disorders resulting in impaired memory, communication, and thought processes. In recent years, clinical research advances in brain aging have focused on the…
Hypernasality is a common characteristic symptom across many motor-speech disorders. For voiced sounds, hypernasality introduces an additional resonance in the lower frequencies and, for unvoiced sounds, there is reduced articulatory…
Alzheimer's dementia (AD) is a neurodegenerative disorder with cognitive decline that commonly impacts language ability. This work extends the paired perplexity approach to detecting AD by using a recent large language model (LLM), the…
In recent years, deep learning methods have achieved great success in various fields due to their strong performance in practical applications. In this paper, we present a light-weight neural network for Parkinson's disease diagnostics, in…
Parkinson's Disease (PD) is the second most common neurodegenerative disorder. The existing assessment method for PD is usually the Movement Disorder Society - Unified Parkinson's Disease Rating Scale (MDS-UPDRS) to assess the severity of…
Background: Subtle changes in spontaneous language production are among the earliest indicators of cognitive decline. Identifying linguistically interpretable markers of dementia can support transparent and clinically grounded screening…
Objective: this study has a twofold goal. First, it aims to improve the understanding of the impact of Dementia of type Alzheimer's Disease (AD) on different aspects of the lexicon. Second, it aims to demonstrate that such aspects of the…
Diagnosis and therapeutic effect assessment of Parkinson disease based on voice data are very important,but its few-shot learning problem is challenging.Although deep learning is good at automatic feature extraction, it suffers from…
Cognitive and neurological impairments are very common, but only a small proportion of affected individuals are diagnosed and treated, partly because of the high costs associated with frequent screening. Detecting pre-illness stages and…
Background: Alzheimer's disease and related dementias (ADRD) are progressive neurodegenerative conditions where early detection is vital for timely intervention and care. Spontaneous speech contains rich acoustic and linguistic markers that…
We investigate the potential association between leucine-rich repeat kinase 2 (LRRK2) mutations and voice. Sustained phonations ('aaah' sounds) were recorded from 7 individuals with LRRK2-associated Parkinson's disease (PD), 17 participants…
Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…
Speech impairments are prevalent biomarkers for Parkinson's Disease (PD), motivating the development of diagnostic techniques using speech data for clinical applications. Although deep acoustic features have shown promise for PD…
This research tests the role of Large Language Models (LLMs) as formal second opinion tools in professional decision-making, particularly focusing on complex medical cases where even experienced physicians seek peer consultation. The work…