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Dementia is associated with language disorders which impede communication. Here, we automatically learn linguistic disorder patterns by making use of a moderately-sized pre-trained language model and forcing it to focus on reformulated…

Computation and Language · Computer Science 2023-10-17 Dimitris Gkoumas , Matthew Purver , Maria Liakata

Alzheimer's disease (AD) is a progressive neurodegenerative disease most often associated with memory deficits and cognitive decline. With the aging population, there has been much interest in automated methods for cognitive impairment…

Audio and Speech Processing · Electrical Eng. & Systems 2023-03-07 Bastiaan Tamm , Rik Vandenberghe , Hugo Van hamme

The USA Food and Drug Administration has accorded increasing importance to patient-reported problems in clinical and research settings. In this paper, we explore one of the largest online datasets comprising 170,141 open-ended self-reported…

Computation and Language · Computer Science 2023-05-09 Lakshmi Arbatti , Abhishek Hosamath , Vikram Ramanarayanan , Ira Shoulson

Hypomimia is a condition in the early stages of the progression of Parkinsons disease that limits the movement of facial muscles, restricting the accurate depiction of facial expressions. Also known as facial masking, this condition is an…

Medical Physics · Physics 2021-11-25 Simoni Mishra

Speech is a rich biomarker that encodes substantial information about the health of a speaker, and thus it has been proposed for the detection of numerous diseases, achieving promising results. However, questions remain about what the…

Audio and Speech Processing · Electrical Eng. & Systems 2024-09-17 Catarina Botelho , Alberto Abad , Tanja Schultz , Isabel Trancoso

Alzheimer's Disease (AD) is nowadays the most common form of dementia, and its automatic detection can help to identify symptoms at early stages, so that preventive actions can be carried out. Moreover, non-intrusive techniques based on…

Computation and Language · Computer Science 2020-11-21 Mireia Farrús , Joan Codina-Filbà

Parkinsons Disease (PD) is a neurodegenerative disorder resulting in motor deficits due to advancing degeneration of dopaminergic neurons. PD patients report experiencing tremor, rigidity, visual impairment, bradykinesia, and several…

Computer Vision and Pattern Recognition · Computer Science 2023-04-05 Krish Desai

Parkinson's disease (PD) is a common neurological disorder characterized by gait impairment. PD has no cure, and an impediment to developing a treatment is the lack of any accepted method to predict disease progression rate. The primary aim…

Signal Processing · Electrical Eng. & Systems 2019-11-26 Vyom Raval , Kevin P. Nguyen , Ashley Gerald , Richard B. Dewey , Albert Montillo

In this paper, we envision a web-based framework that can help anyone, anywhere around the world record a short speech task, and analyze the recorded data to screen for Parkinson's disease (PD). We collected data from 726 unique…

Parkinson's disease (PD) belongs to the class of neurodegenerative disorders that affect the central nervous system. It is usually defined as the gradual loss of dopaminergic neurons in the substantia nigra pars compacta, which causes both…

Neurons and Cognition · Quantitative Biology 2024-11-01 Hina Shaheen , Roderick Melnik

Automatic pathological speech detection approaches yield promising results in identifying various pathologies. These approaches are typically designed and evaluated for phonetically-controlled speech scenarios, where speakers are prompted…

Machine Learning · Computer Science 2024-06-17 Shakeel A. Sheikh , Ina Kodrasi

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and memory loss. Early detection of AD is crucial for effective intervention and treatment. In this paper, we propose a novel approach…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-29 Yu Pu , Wei-Qiang Zhang

Parkinson's disease (PD), a severe and progressive neurological illness, affects millions of individuals worldwide. For effective treatment and management of PD, an accurate and early diagnosis is crucial. This study presents a deep…

Signal Processing · Electrical Eng. & Systems 2023-08-16 Niloufar Delfan , Mohammadreza Shahsavari , Sadiq Hussain , Robertas Damaševičius , U. Rajendra Acharya

One major challenge in the medication of Parkinson's disease is that the severity of the disease, reflected in the patients' motor state, cannot be measured using accessible biomarkers. Therefore, we develop and examine a variety of…

Machine Learning · Computer Science 2019-04-26 Jann Goschenhofer , Franz MJ Pfister , Kamer Ali Yuksel , Bernd Bischl , Urban Fietzek , Janek Thomas

The assessment of Parkinson's disease (PD) poses a significant challenge as it is influenced by various factors which lead to a complex and fluctuating symptom manifestation. Thus, a frequent and objective PD assessment is highly valuable…

Depression commonly co-occurs with neurodegenerative disorders like Multiple Sclerosis (MS), yet the potential of speech-based Artificial Intelligence for detecting depression in such contexts remains unexplored. This study examines the…

Computation and Language · Computer Science 2025-08-26 Monica Gonzalez-Machorro , Uwe Reichel , Pascal Hecker , Helly Hammer , Hesam Sagha , Florian Eyben , Robert Hoepner , Björn W. Schuller

Parkinson's disease (PD) is a debilitating neurological disorder that necessitates precise and early diagnosis for effective patient care. This study aims to develop a diagnostic model capable of achieving both high accuracy and minimizing…

Machine Learning · Computer Science 2024-01-30 Seyedeh Zahra Seyedi Hosseininian , Ahmadreza Tajari , Mohsen Ghalehnoie , Alireza Alfi

Multiscale modelling presents a multifaceted perspective into understanding the mechanisms of the brain and how neurodegenerative disorders like Parkinson's disease (PD) manifest and evolve over time. In this study, we propose a novel…

Neurons and Cognition · Quantitative Biology 2025-09-18 Aaron Herrera , Hina Shaheen

Background and Objective: Parkinson's disease (PD) is the second most common progressive neurological condition after Alzheimer's, characterized by motor and non-motor symptoms. Developing a method to diagnose the condition in its beginning…

Machine Learning · Computer Science 2022-10-05 Paria Ghaheri , Hamid Nasiri , Ahmadreza Shateri , Arman Homafar

This paper enhances dysarthric and dysphonic speech recognition by fine-tuning pretrained automatic speech recognition (ASR) models on the 2023-10-05 data package of the Speech Accessibility Project (SAP), which contains the speech of 253…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-01 Xiuwen Zheng , Bornali Phukon , Mark Hasegawa-Johnson
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