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Medical image analysis faces two critical challenges: scarcity of labeled data and lack of model interpretability, both hindering clinical AI deployment. Few-shot learning (FSL) addresses data limitations but lacks transparency in…

Image and Video Processing · Electrical Eng. & Systems 2026-01-07 Longwei Wang , Ifrat Ikhtear Uddin , KC Santosh

Deep learning (DL) has been used in the automatic diagnosis of Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD) with brain imaging data. However, previous methods have not fully exploited the relation between brain image and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Luoyao Kang , Haifan Gong , Xiang Wan , Haofeng Li

Constructing datasets representative of the target domain is essential for training effective machine learning models. Active learning (AL) is a promising method that iteratively extends training data to enhance model performance while…

Deep learning has the potential to automate many clinically useful tasks in medical imaging. However translation of deep learning into clinical practice has been hindered by issues such as lack of the transparency and interpretability in…

Image and Video Processing · Electrical Eng. & Systems 2022-05-04 Charles Lu , Andreanne Lemay , Ken Chang , Katharina Hoebel , Jayashree Kalpathy-Cramer

Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…

Clinical decision making from magnetic resonance imaging (MRI) combines complementary information from multiple MRI sequences (defined as 'modalities'). MRI image registration aims to geometrically 'pair' diagnoses from different…

Image and Video Processing · Electrical Eng. & Systems 2023-08-07 Chengjia Wang , Giorgos Papanastasiou

How do the neural networks distinguish two images? It is of critical importance to understand the matching mechanism of deep models for developing reliable intelligent systems for many risky visual applications such as surveillance and…

Computer Vision and Pattern Recognition · Computer Science 2021-08-13 Wenliang Zhao , Yongming Rao , Ziyi Wang , Jiwen Lu , Jie Zhou

Deep learning (DL) for predicting Alzheimer's disease (AD) has provided timely intervention in disease progression yet still demands attentive interpretability to explain how their DL models make definitive decisions. Recently,…

Artificial Intelligence · Computer Science 2023-10-06 Kwanseok Oh , Da-Woon Heo , Ahmad Wisnu Mulyadi , Wonsik Jung , Eunsong Kang , Kun Ho Lee , Heung-Il Suk

When we deploy machine learning models in high-stakes medical settings, we must ensure these models make accurate predictions that are consistent with known medical science. Inherently interpretable networks address this need by explaining…

Computer Vision and Pattern Recognition · Computer Science 2021-10-06 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

Deep neural networks for medical image diagnosis often achieve high predictive accuracy while relying on spurious or clinically irrelevant visual cues, limiting their trustworthiness in practice. Post-hoc explanation methods are widely used…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Zubair Faruqui , Rahul Dubey

\textbf{Objective:} Alzheimer's disease (AD) is the most prevalent form of dementia worldwide, encompassing a prodromal stage known as Mild Cognitive Impairment (MCI), where patients may either progress to AD or remain stable. The objective…

Annotating bounding boxes is costly and limits the scalability of object detection. This challenge is compounded by the need to preserve high accuracy while minimizing manual effort in real-world applications. Prior active learning methods…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Rashi Sharma , Justin Timothy C. Bersamin , Karthikk Subramanian

Machine learning methods have shown large potential for the automatic early diagnosis of Alzheimer's Disease (AD). However, some machine learning methods based on imaging data have poor interpretability because it is usually unclear how…

Tabular anomaly detection, which aims at identifying deviant samples, has been crucial in a variety of real-world applications, such as medical disease identification, financial fraud detection, intrusion monitoring, etc. Although recent…

Machine Learning · Computer Science 2025-06-04 Ruiying Lu , Jinhan Liu , Chuan Du , Dandan Guo

Generalized additive models (GAMs) have long been a powerful white-box tool for the intelligible analysis of tabular data, revealing the influence of each feature on the model predictions. Despite the success of neural networks (NNs) in…

Machine Learning · Computer Science 2024-10-08 Guangzhi Xiong , Sanchit Sinha , Aidong Zhang

While interpretable prototype networks offer compelling case-based reasoning for clinical diagnostics, their raw continuous outputs lack the semantic structure required for medical documentation. Bridging this gap via standard…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Alvaro Lopez Pellicer , Plamen Angelov , Marwan Bukhari , Yi Li , Eduardo Soares , Jemma Kerns

Deep learning has achieved widespread success in medical image analysis, leading to an increasing demand for large-scale expert-annotated medical image datasets. Yet, the high cost of annotating medical images severely hampers the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Haoran Wang , Qiuye Jin , Shiman Li , Siyu Liu , Manning Wang , Zhijian Song

The use of machine learning (ML) techniques in the biomedical field has become increasingly important, particularly with the large amounts of data generated by the aftermath of the COVID-19 pandemic. However, due to the complex nature of…

Machine Learning · Computer Science 2023-03-17 Anthony Onoja , Francesco Raimondi

Melanoma is a prevalent lethal type of cancer that is treatable if diagnosed at early stages of development. Skin lesions are a typical indicator for diagnosing melanoma but they often led to delayed diagnosis due to high similarities of…

Machine Learning · Computer Science 2023-03-28 Ruitong Sun , Mohammad Rostami

In this study, we propose a tailored DL framework for patient-specific performance that leverages the behavior of a model intentionally overfitted to a patient-specific training dataset augmented from the prior information available in an…

Machine Learning · Computer Science 2022-04-06 Jaehee Chun , Justin C. Park , Sven Olberg , You Zhang , Dan Nguyen , Jing Wang , Jin Sung Kim , Steve Jiang
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