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Related papers: Hypothesis Generation with Large Language Models

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Hypothesis generation is a fundamental step in scientific discovery, yet it is increasingly challenged by information overload and disciplinary fragmentation. Recent advances in Large Language Models (LLMs) have sparked growing interest in…

Large language models (LLMs) increasingly help people solve problems, from debugging code to repairing machinery. This process requires generating plausible hypotheses from partial descriptions, then updating them as more information…

Machine Learning · Computer Science 2026-05-08 Hua-Dong Xiong

The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

Large Language Models (LLMs) are transforming scientific hypothesis generation and validation by enabling information synthesis, latent relationship discovery, and reasoning augmentation. This survey provides a structured overview of…

Significant scientific discoveries have driven the progress of human civilisation. The explosion of scientific literature and data has created information barriers across disciplines that have slowed the pace of scientific discovery. Large…

Computation and Language · Computer Science 2023-11-13 Biqing Qi , Kaiyan Zhang , Haoxiang Li , Kai Tian , Sihang Zeng , Zhang-Ren Chen , Bowen Zhou

Large language models (LLMs) are becoming a one-fits-many solution, but they sometimes hallucinate or produce unreliable output. In this paper, we investigate how hypothesis ensembling can improve the quality of the generated text for the…

Computation and Language · Computer Science 2023-10-18 António Farinhas , José G. C. de Souza , André F. T. Martins

Materials discovery and design are essential for advancing technology across various industries by enabling the development of application-specific materials. Recent research has leveraged Large Language Models (LLMs) to accelerate this…

Computation and Language · Computer Science 2025-02-11 Shrinidhi Kumbhar , Venkatesh Mishra , Kevin Coutinho , Divij Handa , Ashif Iquebal , Chitta Baral

Since the advent of Large Language Models (LLMs), efforts have largely focused on improving their instruction-following and deductive reasoning abilities, leaving open the question of whether these models can truly discover new knowledge.…

Computation and Language · Computer Science 2025-10-31 Kaiyu He , Zhiyu Chen

Large pre-trained language models (LMs) have been shown to perform surprisingly well when fine-tuned on tasks that require commonsense and world knowledge. However, in end-to-end architectures, it is difficult to explain what is the…

Computation and Language · Computer Science 2020-04-14 Veronica Latcinnik , Jonathan Berant

Large Language models have demonstrated promising performance in research ideation across scientific domains. Hypothesis development, the process of generating a highly specific declarative statement connecting a research idea with…

Artificial Intelligence · Computer Science 2025-08-25 Rosni Vasu , Chandrayee Basu , Bhavana Dalvi Mishra , Cristina Sarasua , Peter Clark , Abraham Bernstein

AI holds promise for transforming scientific processes, including hypothesis generation. Prior work on hypothesis generation can be broadly categorized into theory-driven and data-driven approaches. While both have proven effective in…

Artificial Intelligence · Computer Science 2025-01-10 Haokun Liu , Yangqiaoyu Zhou , Mingxuan Li , Chenfei Yuan , Chenhao Tan

Large Language Models (LLMs) show impressive inductive reasoning capabilities, enabling them to generate hypotheses that could generalize effectively to new instances when guided by in-context demonstrations. However, in real-world…

Artificial Intelligence · Computer Science 2024-12-19 Zhuo Liu , Ding Yu , Hangfeng He

There is growing interest in hypothesis generation with large language models (LLMs). However, fundamental questions remain: what makes a good hypothesis, and how can we systematically evaluate methods for hypothesis generation? To address…

Artificial Intelligence · Computer Science 2026-02-12 Haokun Liu , Sicong Huang , Jingyu Hu , Yangqiaoyu Zhou , Chenhao Tan

Hypothesis formulation and testing are central to empirical research. A strong hypothesis is a best guess based on existing evidence and informed by a comprehensive view of relevant literature. However, with exponential increase in the…

Computation and Language · Computer Science 2024-03-27 Sai Koneru , Jian Wu , Sarah Rajtmajer

Inductive Logic Programming (ILP) is a principled approach for generalizing regularities from data and constructing hypotheses as interpretable logic programs. However, a key limitation is its reliance on expert-crafted language bias - the…

Artificial Intelligence · Computer Science 2026-01-21 Yang Yang , Jiemin Wu , Yutao Yue

Large Language Models (LLMs) have in recent years demonstrated impressive prowess in natural language generation. A common practice to improve generation diversity is to sample multiple outputs from the model. However, there lacks a simple…

Computation and Language · Computer Science 2022-09-23 Xingdi Yuan , Tong Wang , Yen-Hsiang Wang , Emery Fine , Rania Abdelghani , Pauline Lucas , Hélène Sauzéon , Pierre-Yves Oudeyer

Hypothetical induction is recognized as the main reasoning type when scientists make observations about the world and try to propose hypotheses to explain those observations. Past research on hypothetical induction is under a constrained…

Computation and Language · Computer Science 2024-06-13 Zonglin Yang , Xinya Du , Junxian Li , Jie Zheng , Soujanya Poria , Erik Cambria

Large language models (LLMs) have shown significant potential in scientific disciplines such as biomedicine, particularly in hypothesis generation, where they can analyze vast literature, identify patterns, and suggest research directions.…

Computation and Language · Computer Science 2025-06-10 Guangzhi Xiong , Eric Xie , Corey Williams , Myles Kim , Amir Hassan Shariatmadari , Sikun Guo , Stefan Bekiranov , Aidong Zhang

To enhance the quality of generated stories, recent story generation models have been investigating the utilization of higher-level attributes like plots or commonsense knowledge. The application of prompt-based learning with large language…

Computation and Language · Computer Science 2023-07-25 Zhuohan Xie , Trevor Cohn , Jey Han Lau

This paper delves into the capabilities of large language models (LLMs), specifically focusing on advancing the theoretical comprehension of chain-of-thought prompting. We investigate how LLMs can be effectively induced to generate a…

Computation and Language · Computer Science 2024-06-07 Rasul Tutunov , Antoine Grosnit , Juliusz Ziomek , Jun Wang , Haitham Bou-Ammar
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