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Cognitive systems generally require a human to translate a problem definition into some specification that the cognitive system can use to attempt to solve the problem or perform the task. In this paper, we illustrate that large language…
Developing artificial intelligence (AI) for clinical research requires a comprehensive data foundation that supports model training and rigorous evaluation. Here, we introduce TrialPanorama, a large-scale structured resource that aggregates…
Training mental health clinicians to conduct standardized clinical assessments is challenging due to a lack of scalable, realistic practice opportunities, which can impact data quality in clinical trials. To address this gap, we introduce a…
We propose DISC-MedLLM, a comprehensive solution that leverages Large Language Models (LLMs) to provide accurate and truthful medical response in end-to-end conversational healthcare services. To construct high-quality Supervised…
Large language models (LLMs) can capture rich representations of concepts that are useful for real-world tasks. However, language alone is limited. While existing LLMs excel at text-based inferences, health applications require that models…
Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…
Clinical reasoning in medicine is a hypothesis-driven process where physicians refine diagnoses from limited information through targeted history, physical examination, and diagnostic investigations. In contrast, current medical benchmarks…
This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…
Artificial intelligence systems, particularly large language models (LLMs), are increasingly being employed in high-stakes decisions that impact both individuals and society at large, often without adequate safeguards to ensure safety,…
The intricate relationship between genetic variation and human diseases has been a focal point of medical research, evidenced by the identification of risk genes regarding specific diseases. The advent of advanced genome sequencing…
This study investigates the efficacy of Large Language Models (LLMs) in interactive language therapy for high-functioning autistic adolescents. With the rapid advancement of artificial intelligence, particularly in natural language…
Traditionally, AI research in medical diagnosis has largely centered on image analysis. While this has led to notable advancements, the absence of patient-reported symptoms continues to hinder diagnostic accuracy. To address this, we…
Full-process clinical diagnosis in the real world encompasses the entire diagnostic workflow that begins with only an ambiguous chief complaint. While artificial intelligence (AI), particularly large language models (LLMs), is transforming…
Digital twin technology is a transformative innovation driving the digital transformation and intelligent optimization of manufacturing systems. By integrating real-time data with computational models, digital twins enable continuous…
Understanding the dynamics of counseling conversations is an important task, yet it is a challenging NLP problem regardless of the recent advance of Transformer-based pre-trained language models. This paper proposes a systematic approach to…
LLM-based agents have emerged as transformative tools capable of executing complex tasks through iterative planning and action, achieving significant advancements in understanding and addressing user needs. Yet, their effectiveness remains…
This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…
Psychological consultation is essential for improving mental health and well-being, yet challenges such as the shortage of qualified professionals and scalability issues limit its accessibility. To address these challenges, we explore the…
The exponential growth of text-based data in domains such as healthcare, education, and social sciences has outpaced the capacity of traditional qualitative analysis methods, which are time-intensive and prone to subjectivity. Large…
Large language models (LLMs) have shown remarkable capabilities in various natural language tasks and are increasingly being applied in healthcare domains. This work demonstrates a new LLM-powered disease risk assessment approach via…