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Development of new medications is a very lengthy and costly process. Finding novel indications for existing drugs, or drug repositioning, can serve as a useful strategy to shorten the development cycle. In this study, we present an approach…

Genomics · Quantitative Biology 2017-12-13 Kai Zhao , Hon-Cheong So

Disorganized thinking is a key diagnostic indicator of schizophrenia-spectrum disorders. Recently, clinical estimates of the severity of disorganized thinking have been shown to correlate with measures of how difficult speech transcripts…

Computation and Language · Computer Science 2025-03-27 Changye Li , Weizhe Xu , Serguei Pakhomov , Ellen Bradley , Dror Ben-Zeev , Trevor Cohen

Depression is one of the most prevalent and debilitating mental health conditions worldwide, frequently underdiagnosed and undertreated. The proliferation of social media platforms provides a rich source of naturalistic linguistic signals…

Computation and Language · Computer Science 2026-04-23 Giorgia Gulino , Manuel Petrucci

The early identification and intervention of latent depression are of significant societal importance for mental health governance. While current automated detection methods based on social media have shown progress, their decision-making…

Quantitative Methods · Quantitative Biology 2025-12-17 Junwei Kuang , Jiaheng Xie , Zhijun Yan

Mental disorders pose a global challenge, aggravated by the shortage of qualified mental health professionals. Mental disorder prediction from social media posts by current LLMs is challenging due to the complexities of sequential text data…

Computation and Language · Computer Science 2024-10-08 Raja Kumar , Kishan Maharaj , Ashita Saxena , Pushpak Bhattacharyya

Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

Using Instagram data from 166 individuals, we applied machine learning tools to successfully identify markers of depression. Statistical features were computationally extracted from 43,950 participant Instagram photos, using color analysis,…

Social and Information Networks · Computer Science 2016-08-16 Andrew G. Reece , Christopher M. Danforth

Large-scale collaborative analysis of brain imaging data, in psychiatry and neu-rology, offers a new source of statistical power to discover features that boost ac-curacy in disease classification, differential diagnosis, and outcome…

The detection of depression through non-verbal cues has gained significant attention. Previous research predominantly centred on identifying depression within the confines of controlled laboratory environments, often with the supervision of…

Computation and Language · Computer Science 2024-06-18 Palash Moon , Pushpak Bhattacharyya

Mental disorders such as depression and suicidal ideation are hazardous, affecting more than 300 million people over the world. However, on social media, mental disorder symptoms can be observed, and automated approaches are increasingly…

Information Retrieval · Computer Science 2023-01-26 Ramin Safa , S. A. Edalatpanah , Ali Sorourkhah

Schizophrenia is a severe yet treatable mental disorder, it is diagnosed using a multitude of primary and secondary symptoms. Diagnosis and treatment for each individual depends on the severity of the symptoms, therefore there is a need for…

Human-Computer Interaction · Computer Science 2023-10-26 Niki Maria Foteinopoulou , Ioannis Patras

Lung cancer is a major issue in worldwide public health, requiring early diagnosis using stable techniques. This work begins a thorough investigation of the use of machine learning (ML) methods for precise classification of lung cancer…

Computer Vision and Pattern Recognition · Computer Science 2025-01-31 Shayli Farshchiha , Salman Asoudeh , Maryam Shavali Kuhshuri , Mehrshad Eisaeid , Mohamadreza Azadie , Saba Hesaraki

College students are increasingly affected by stress, anxiety, and depression, yet face barriers to traditional mental health care. This study evaluated the efficacy of a mobile health (mHealth) intervention, Mental Health Evaluation and…

Human-Computer Interaction · Computer Science 2025-05-28 Alan Ta , Nilsu Salgin , Mustafa Demir , Kala Phillips Reindel , Ranjana K. Mehta , Anthony McDonald , Carly McCord , Farzan Sasangohar

Millions of people openly share mental health struggles on social media, providing rich data for early detection of conditions such as depression, bipolar disorder, etc. However, most prior Natural Language Processing (NLP) research has…

Computation and Language · Computer Science 2025-09-23 Khalid Hasan , Jamil Saquer , Yifan Zhang

The most common mental disorders experienced by a person in daily life are depression and anxiety. Social stigma makes people with depression and anxiety neglected by their surroundings. Therefore, they turn to social media like Twitter for…

Computation and Language · Computer Science 2023-01-12 Kuncahyo Setyo Nugroho , Ismail Akbar , Affi Nizar Suksmawati , Istiadi

Depression is a common mental disorder. Automatic depression detection tools using speech, enabled by machine learning, help early screening of depression. This paper addresses two limitations that may hinder the clinical implementations of…

Computation and Language · Computer Science 2023-10-09 Qingkun Deng , Saturnino Luz , Sofia de la Fuente Garcia

Massive social media data can reflect people's authentic thoughts, emotions, communication, etc., and therefore can be analyzed for early detection of mental health problems such as depression. Existing works about early depression…

Social and Information Networks · Computer Science 2025-03-04 Chen Chen , Mingwei Li , Fenghuan Li , Haopeng Chen , Yuankun Lin

Deep learning (DL) models have achieved paradigm-changing performance in many fields with high dimensional data, such as images, audio, and text. However, the black-box nature of deep neural networks is a barrier not just to adoption in…

Machine Learning · Computer Science 2020-02-25 Parmita Mehta , Stephen Portillo , Magdalena Balazinska , Andrew Connolly

Understanding how individuals with Parkinson's disease (PD) describe cognitive experiences in their daily lives can offer valuable insights into disease-related cognitive and emotional changes. However, extracting such information from…

Computation and Language · Computer Science 2025-11-13 Varada Khanna , Nilay Bhatt , Ikgyu Shin , Sule Tinaz , Yang Ren , Hua Xu , Vipina K. Keloth

The primary aim of this paper is to comprehend, assess, and analyze the role, relevance, and efficiency of machine learning models in predicting heart disease risks using clinical data. While the importance of heart disease risk prediction…

Machine Learning · Computer Science 2024-10-22 Balaji Shesharao Ingole , Vishnu Ramineni , Nikhil Bangad , Koushik Kumar Ganeeb , Priyankkumar Patel