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Advances in microscopy imaging enable researchers to visualize structures at the nanoscale level thereby unraveling intricate details of biological organization. However, challenges such as image noise, photobleaching of fluorophores, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-19 Pamela Osuna-Vargas , Maren H. Wehrheim , Lucas Zinz , Johanna Rahm , Ashwin Balakrishnan , Alexandra Kaminer , Mike Heilemann , Matthias Kaschube

Recently, text-to-image diffusion models become a new paradigm in image processing fields, including content generation, image restoration and image-to-image translation. Given a target prompt, Denoising Diffusion Probabilistic Models…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Yupei Lin , Xiaoyu Xian , Yukai Shi , Liang Lin

Segmentation masks of pathological areas are useful in many medical applications, such as brain tumour and stroke management. Moreover, healthy counterfactuals of diseased images can be used to enhance radiologists' training files and to…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Alessandro Fontanella , Grant Mair , Joanna Wardlaw , Emanuele Trucco , Amos Storkey

Learning diffusion bridge models is easy; making them fast and practical is an art. Diffusion bridge models (DBMs) are a promising extension of diffusion models for applications in image-to-image translation. However, like many modern…

Machine Learning · Computer Science 2025-08-19 Nikita Gushchin , David Li , Daniil Selikhanovych , Evgeny Burnaev , Dmitry Baranchuk , Alexander Korotin

Diffusion models (DMs) have recently achieved significant success in wireless communications systems due to their denoising capabilities. The broadcast nature of wireless signals makes them susceptible not only to Gaussian noise, but also…

Information Theory · Computer Science 2025-05-27 Tong Wu , Zhiyong Chen , Dazhi He , Feng Yang , Meixia Tao , Xiaodong Xu , Wenjun Zhang , Ping Zhang

Diffusion models have recently demonstrated an impressive ability to address inverse problems in an unsupervised manner. While existing methods primarily focus on modifying the posterior sampling process, the potential of the forward…

Computer Vision and Pattern Recognition · Computer Science 2024-05-03 Gongye Liu , Haoze Sun , Jiayi Li , Fei Yin , Yujiu Yang

Imputation of missing images via source-to-target modality translation can improve diversity in medical imaging protocols. A pervasive approach for synthesizing target images involves one-shot mapping through generative adversarial networks…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Muzaffer Özbey , Onat Dalmaz , Salman UH Dar , Hasan A Bedel , Şaban Özturk , Alper Güngör , Tolga Çukur

Multimodal remote sensing image registration aligns images from different sensors for data fusion and analysis. However, existing methods often struggle to extract modality-invariant features when faced with large nonlinear radiometric…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Xiaochen Wei , Weiwei Guo , Wenxian Yu , Feiming Wei , Dongying Li

We consider a class of inverse problems characterized by forward operators that are partially specified, non-smooth, and non-differentiable. Although generative inverse solvers have made significant progress, we find that these forward…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Sattwik Basu , Chaitanya Amballa , Zhongweiyang Xu , Jorge Vančo Sampedro , Srihari Nelakuditi , Romit Roy Choudhury

Four-dimensional computed tomography (4DCT) is essential for medical imaging applications like radiotherapy, which demand precise respiratory motion representation. Traditional methods for reconstructing 4DCT data suffer from artifacts and…

Medical Physics · Physics 2025-07-21 Antoine De Paepe , Alexandre Bousse , Clémentine Phung-Ngoc , Dimitris Visvikis

Diffusion models, which iteratively denoise data samples to synthesize high-quality outputs, have achieved empirical success across domains. However, optimizing these models for downstream tasks often involves nested bilevel structures,…

Machine Learning · Computer Science 2025-08-06 Quan Xiao , Hui Yuan , A F M Saif , Gaowen Liu , Ramana Kompella , Mengdi Wang , Tianyi Chen

Multi-modality image fusion aims to combine different modalities to produce fused images that retain the complementary features of each modality, such as functional highlights and texture details. To leverage strong generative priors and…

Computer Vision and Pattern Recognition · Computer Science 2023-08-24 Zixiang Zhao , Haowen Bai , Yuanzhi Zhu , Jiangshe Zhang , Shuang Xu , Yulun Zhang , Kai Zhang , Deyu Meng , Radu Timofte , Luc Van Gool

Inverting real images into the noise space is essential for editing tasks using diffusion models, yet existing methods produce non-Gaussian noise with poor editability due to the inaccuracy in early noising steps. We identify the root…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Chen Min , Enze Jiang , Jishen Peng , Zheng Ma

Anomaly detection in medical imaging plays a crucial role in identifying pathological regions across various imaging modalities, such as brain MRI, liver CT, and carotid ultrasound (US). However, training fully supervised segmentation…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yuan Bi , Lucie Huang , Ricarda Clarenbach , Reza Ghotbi , Angelos Karlas , Nassir Navab , Zhongliang Jiang

Recent advances in generative modeling with diffusion processes (DPs) enabled breakthroughs in image synthesis. Despite impressive image quality, these models have various prompt compliance problems, including low recall in generating…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Deepak Sridhar , Abhishek Peri , Rohith Rachala , Nuno Vasconcelos

Inverse problems are key issues in several scientific areas, including signal processing and medical imaging. Data-driven approaches for inverse problems aim for learning model and regularization parameters from observed data samples, and…

Optimization and Control · Mathematics 2024-11-28 Mathias Staudigl , Simon Weissmann , Tristan van Leeuwen

This paper proposes a data-driven model for solving the inverse problem of electrocardiography, the mathematical problem that forms the basis of electrocardiographic imaging (ECGI). We present a conditional diffusion framework that learns a…

Machine Learning · Computer Science 2026-01-27 Ramiro Valdes Jara , Adam Meyers

Our goal is to extend the denoising diffusion implicit model (DDIM) to general diffusion models~(DMs) besides isotropic diffusions. Instead of constructing a non-Markov noising process as in the original DDIM, we examine the mechanism of…

Machine Learning · Computer Science 2023-03-24 Qinsheng Zhang , Molei Tao , Yongxin Chen

Solving partial differential equations (PDEs) on fine spatio-temporal scales for high-fidelity solutions is critical for numerous scientific breakthroughs. Yet, this process can be prohibitively expensive, owing to the inherent complexities…

Numerical Analysis · Mathematics 2024-04-09 Yulong Lu , Wuzhe Xu

Detecting out-of-distribution (OOD) inputs is pivotal for deploying safe vision systems in open-world environments. We revisit diffusion models, not as generators, but as universal perceptual templates for OOD detection. This research…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Lemar Abdi , Amaan Valiuddin , Francisco Caetano , Christiaan Viviers , Fons van der Sommen
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