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We consider the problem of controlling an invasive mechanical ventilator for pressure-controlled ventilation: a controller must let air in and out of a sedated patient's lungs according to a trajectory of airway pressures specified by a…

The COVID-19 pandemic has highlighted the importance of supply chains and the role of digital management to react to dynamic changes in the environment. In this work, we focus on developing dynamic inventory ordering policies for a…

Machine Learning · Computer Science 2023-03-23 Julien Siems , Maximilian Schambach , Sebastian Schulze , Johannes S. Otterbach

Reinforcement learning (RL) is a powerful machine learning technique that enables an intelligent agent to learn an optimal policy that maximizes the cumulative rewards in sequential decision making. Most of methods in the existing…

Machine Learning · Statistics 2023-01-06 Chengchun Shi , Zhengling Qi , Jianing Wang , Fan Zhou

Reinforcement Learning (RL) bears the promise of being a game-changer in many applications. However, since most of the literature in the field is currently focused on opaque models, the use of RL in high-stakes scenarios, where…

Machine Learning · Computer Science 2025-01-22 Leonardo Lucio Custode , Giovanni Iacca

Imagine a patient in critical condition. What and when should be measured to forecast detrimental events, especially under the budget constraints? We answer this question by deep reinforcement learning (RL) that jointly minimizes the…

Machine Learning · Computer Science 2019-06-11 Chun-Hao Chang , Mingjie Mai , Anna Goldenberg

When using a tool, the grasps used for picking it up, reposing, and holding it in a suitable pose for the desired task could be distinct. Therefore, a key challenge for autonomous in-hand tool manipulation is finding a sequence of grasps…

Robotics · Computer Science 2023-04-06 Ethan K. Gordon , Rana Soltani Zarrin

Reinforcement learning (RL) has emerged as a powerful approach for tackling complex medical decision-making problems such as treatment planning, personalized medicine, and optimizing the scheduling of surgeries and appointments. It has…

Computation and Language · Computer Science 2023-10-31 Ying Liu , Haozhu Wang , Huixue Zhou , Mingchen Li , Yu Hou , Sicheng Zhou , Fang Wang , Rama Hoetzlein , Rui Zhang

As critically ill patients frequently develop anemia or coagulopathy, transfusion of blood products is a frequent intervention in the Intensive Care Units (ICU). However, inappropriate transfusion decisions made by physicians are often…

Machine Learning · Computer Science 2022-06-30 Yuqing Wang , Yun Zhao , Linda Petzold

Demand-side flexibility is gaining importance as a crucial element in the energy transition process. Accounting for about 25% of final energy consumption globally, the residential sector is an important (potential) source of energy…

Systems and Control · Electrical Eng. & Systems 2024-03-19 Gargya Gokhale , Seyed Soroush Karimi Madahi , Bert Claessens , Chris Develder

This paper presents a trustworthy reinforcement learning approach for the control of industrial compressed air systems. We develop a framework that enables safe and energy-efficient operation under realistic boundary conditions and…

Machine Learning · Computer Science 2025-12-23 Vincent Bezold , Patrick Wagner , Jakob Hofmann , Marco Huber , Alexander Sauer

Multi-objective reinforcement learning (MORL) aims at optimising several, often conflicting goals to improve the flexibility and reliability of RL in practical tasks. This is typically achieved by finding a set of diverse, non-dominated…

Artificial Intelligence · Computer Science 2026-02-06 Qiyue Xia , Tianwei Wang , J. Michael Herrmann

There has been considerable interest in leveraging RL and stochastic control methods to learn optimal treatment strategies for critically ill patients, directly from observational data. However, there is significant ambiguity on the control…

Machine Learning · Computer Science 2022-07-21 Thesath Nanayakkara

In the field of high-performance computing (HPC), there has been recent exploration into the use of deep reinforcement learning for cluster scheduling (DRL scheduling), which has demonstrated promising outcomes. However, a significant…

Machine Learning · Computer Science 2024-03-26 Boyang Li , Zhiling Lan , Michael E. Papka

A key impediment to reinforcement learning (RL) in real applications with limited, batch data is defining a reward function that reflects what we implicitly know about reasonable behaviour for a task and allows for robust off-policy…

Machine Learning · Computer Science 2019-05-31 Niranjani Prasad , Barbara E Engelhardt , Finale Doshi-Velez

Many organisms and cell types, from bacteria to cancer cells, exhibit a remarkable ability to adapt to fluctuating environments. Additionally, cells can leverage a memory of past environments to better survive previously-encountered…

Machine Learning · Computer Science 2025-01-29 Josiah C. Kratz , Jacob Adamczyk

In aims to uncover insights into medical decision-making embedded within observational data from clinical settings, we present a novel application of Inverse Reinforcement Learning (IRL) that identifies suboptimal clinician actions based on…

Interactive adaptive systems powered by Reinforcement Learning (RL) have many potential applications, such as intelligent tutoring systems. In such systems there is typically an external human system designer that is creating, monitoring…

Artificial Intelligence · Computer Science 2020-04-06 Ramtin Keramati , Emma Brunskill

We introduce a reinforcement learning (RL) based adaptive optimization algorithm for aerodynamic shape optimization focused on dimensionality reduction. The form in which RL is applied here is that of a surrogate-based, actor-critic policy…

Sampling-based model predictive control (MPC) has found significant success in optimal control problems with non-smooth system dynamics and cost function. Many machine learning-based works proposed to improve MPC by a) learning or…

Machine Learning · Computer Science 2024-01-08 Sungwook Yang , Chaoying Pei , Ran Dai , Chuangchuang Sun

Reinforcement learning (RL) is concerned with how intelligence agents take actions in a given environment to maximize the cumulative reward they receive. In healthcare, applying RL algorithms could assist patients in improving their health…

Machine Learning · Statistics 2025-04-21 Chengchun Shi