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In the mammalian brain newly acquired memories depend on the hippocampus for maintenance and recall, but over time these functions are taken over by the neocortex through a process called systems consolidation. However, reactivation of a…

Neurons and Cognition · Quantitative Biology 2019-03-29 Peter Helfer , Thomas R. Shultz

In the mammalian brain, newly acquired memories depend on the hippocampus for maintenance and recall, but over time the neocortex takes over these functions, rendering memories hippocampus-independent. The process responsible for this…

Neurons and Cognition · Quantitative Biology 2021-07-02 Peter Helfer , Thomas R. Shultz

The standard model of memory consolidation foresees that memories are initially recorded in the hippocampus, while features that capture higher-level generalisations of data are created in the cortex, where they are stored for a possibly…

Neurons and Cognition · Quantitative Biology 2017-06-20 Alessandro Fontana

Standard few-shot experiments involve learning to efficiently match previously unseen samples by class. We claim that few-shot learning should be long term, assimilating knowledge for the future, without forgetting previous concepts. In the…

Machine Learning · Computer Science 2021-05-12 Gideon Kowadlo , Abdelrahman Ahmed , David Rawlinson

The primate heteromodal cortex presents an evident functional modularity at a mesoscopic level, with physiological and anatomical evidence pointing to it as likely substrate of long-term memory. In order to investigate some of its…

Neurons and Cognition · Quantitative Biology 2021-12-09 Carlo Fulvi Mari

Complementary Learning Systems theory holds that intelligent agents need two learning systems. Semantic memory is encoded in the neocortex with dense, overlapping representations and acquires structured knowledge. Episodic memory is encoded…

Machine Learning · Computer Science 2025-09-03 Lucie Fontaine , Frédéric Alexandre

Standard accounts of memory consolidation emphasise the stabilisation of stored representations, but struggle to explain representational drift, semanticisation, or the necessity of offline replay. Here we propose that high-capacity…

Neurons and Cognition · Quantitative Biology 2026-03-06 Zafeirios Fountas , Adnan Oomerjee , Haitham Bou-Ammar , Jun Wang , Neil Burgess

We show that a model of the hippocampus introduced recently by Scarpetta, Zhaoping & Hertz ([2002] Neural Computation 14(10):2371-96), explains the theta phase precession phenomena. In our model, the theta phase precession comes out as a…

Neurons and Cognition · Quantitative Biology 2007-05-23 Silvia Scarpetta , Maria Marinaro

Associative memories in the brain receive and store patterns of activity registered by the sensory neurons, and are able to retrieve them when necessary. Due to their importance in human intelligence, computational models of associative…

Machine Learning · Computer Science 2021-09-17 Tommaso Salvatori , Yuhang Song , Yujian Hong , Simon Frieder , Lei Sha , Zhenghua Xu , Rafal Bogacz , Thomas Lukasiewicz

Hippocampal CA3 is crucial for the formation of long-term associative memory. It has a heavily recurrent connectivity, and memories are thought to be stored as memory engrams in the CA3. However, despite its importance for memory storage…

Neurons and Cognition · Quantitative Biology 2017-04-26 Yansong Chua , Cheston Tan

The spiking activity of principal cells in mammalian hippocampus encodes an internalized neuronal representation of the ambient space---a cognitive map. Once learned, such a map enables the animal to navigate a given environment for a long…

Neurons and Cognition · Quantitative Biology 2017-10-10 Andrey Babichev , Dmitriy Morozov , Yuri Dabaghian

Continual learning (CL) in the brain is facilitated by a complex set of mechanisms. This includes the interplay of multiple memory systems for consolidating information as posited by the complementary learning systems (CLS) theory and…

Neural and Evolutionary Computing · Computer Science 2022-06-09 Fahad Sarfraz , Elahe Arani , Bahram Zonooz

Cortical networks can maintain memories for decades despite the short lifetime of synaptic strength. Can a neural network store long-lasting memories in unstable synapses? Here, we study the effects of random noise on the stability of…

Neurons and Cognition · Quantitative Biology 2012-06-01 Yi Wei , Alexei A. Koulakov

Codifying memories is one of the fundamental problems of modern Neuroscience. The functional mechanisms behind this phenomenon remain largely unknown. Experimental evidence suggests that some of the memory functions are performed by…

Neurons and Cognition · Quantitative Biology 2022-05-17 Ivan Y. Tyukin , Alexander N. Gorban , Carlos Calvo , Julia Makarova , Valeri A. Makarov

Dense Associative Memories or Modern Hopfield Networks have many appealing properties of associative memory. They can do pattern completion, store a large number of memories, and can be described using a recurrent neural network with a…

Neural and Evolutionary Computing · Computer Science 2021-07-29 Dmitry Krotov

Continual acquisition of novel experience without interfering previously learned knowledge, i.e. continual learning, is critical for artificial neural networks, but limited by catastrophic forgetting. A neural network adjusts its parameters…

Machine Learning · Computer Science 2022-02-15 Liyuan Wang , Bo Lei , Qian Li , Hang Su , Jun Zhu , Yi Zhong

What is the physiological basis of long-term memory? The prevailing view in neuroscience attributes changes in synaptic efficacy to memory acquisition. This view implies that stable memories correspond to stable connectivity patterns.…

Neurons and Cognition · Quantitative Biology 2019-10-09 Lee Susman , Naama Brenner , Omri Barak

The nervous system, more specifically, the brain, is capable of solving complex problems simply and efficiently, far surpassing modern computers. In this regard, neuromorphic engineering is a research field that focuses on mimicking the…

Neural and Evolutionary Computing · Computer Science 2022-06-13 Daniel Casanueva-Morato , Alvaro Ayuso-Martinez , Juan P. Dominguez-Morales , Angel Jimenez-Fernandez , Gabriel Jimenez-Moreno

Sequence memory is an essential attribute of natural and artificial intelligence that enables agents to encode, store, and retrieve complex sequences of stimuli and actions. Computational models of sequence memory have been proposed where…

Neural and Evolutionary Computing · Computer Science 2023-11-06 Hamza Tahir Chaudhry , Jacob A. Zavatone-Veth , Dmitry Krotov , Cengiz Pehlevan

Memories in neural system are shaped through the interplay of neural and learning dynamics under external inputs. By introducing a simple local learning rule to a neural network, we found that the memory capacity is drastically increased by…

Adaptation and Self-Organizing Systems · Physics 2020-07-01 Tomoki Kurikawa , Omri Barak , Kunihiko Kaneko
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