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Tree-based regression models are widely used in supervised learning, with the Classification and Regression Tree (CART) algorithm serving as a standard reference. CART construction involves solving a sequence of split-selection optimization…

Computation · Statistics 2026-05-08 Iro René Kouarfate , Maxime Dion , Anne MacKay , Mathieu Pigeon

Multi-period stock-keeping unit (SKU) allocation in supply chains is a combinatorial optimization problem that is both NP-hard and operationally critical, requiring simultaneous attention to profitability, feasibility, and diversity.…

Quadratic unconstrained binary optimization (QUBO) is a field of operations research that is attracting growing interest due to the recent availability of quantum hardware targeted at solving QUBO problems. However, practical adoption is…

Software Engineering · Computer Science 2026-01-22 Lodovica Marchesi , Amal Nasharti , Michele Marchesi

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

Over the last decade, concepts such as industry 4.0 and the Internet of Things (IoT) have contributed to the increase in the availability and affordability of sensing technology. In this context, Structural Health Monitoring (SHM) arises as…

Systems and Control · Electrical Eng. & Systems 2024-01-10 Gabriel San Martin Silva , Enrique Lopez Droguett

With the advances in customized hardware for quantum annealing and digital/CMOS Annealing, Quadratic Unconstrained Binary Optimization (QUBO) models have received growing attention in the optimization literature. Motivated by an existing…

Quantum Physics · Physics 2024-04-05 Oksana Pichugina , Yingcong Tan , Christopher Beck

Quantum Approximate Optimization Algorithm (QAOA) is one of the most short-term promising quantum-classical algorithm to solve unconstrained combinatorial optimization problems. It alternates between the execution of a parametrized quantum…

Optimization and Control · Mathematics 2024-11-18 Camille Grange , Marion Lavignac , Valentina Pozzoli , Eric Bourreau

Quadratic Unconstrained Binary Optimization (QUBO) is a combinatorial optimization to find an optimal binary solution vector that minimizes the energy value defined by a quadratic formula of binary variables in the vector. As many NP-hard…

Performance · Computer Science 2023-10-19 Koji Nakano , Daisuke Takafuji , Yasuaki Ito , Takashi Yazane , Junko Yano , Shiro Ozaki , Ryota Katsuki , Rie Mori

This paper presents key enhancements to our previous work~\cite{naghmouchi2024mixed} on a hybrid Benders decomposition (HBD) framework for solving mixed integer linear programs (MILPs). In our approach, the master problem is reformulated as…

Quantum Physics · Physics 2026-01-23 Anna Joliot , M. Yassine Naghmouchi , Wesley Coelho

Quantum computing is poised to transform the financial industry, yet its advantages over traditional methods have not been evidenced. As this technology rapidly evolves, benchmarking is essential to fairly evaluate and compare different…

Optimization and Control · Mathematics 2025-02-11 Ying Chen , Thorsten Koch , Hanqiu Peng , Hongrui Zhang

We use exact enumeration to characterize the solutions of quadratic unconstrained binary optimization problems of less than 21 variables in terms of their distributions of Hamming distances to close-by solutions. We also perform experiments…

Quantum Physics · Physics 2025-11-04 Vrinda Mehta , Fengping Jin , Kristel Michielsen , Hans De Raedt

Quadratic Unconstrained Binary Optimization (QUBO) is recognized as a unifying framework for modeling a wide range of problems. Problems can be solved with commercial solvers customized for solving QUBO and since QUBO have degree two, it is…

Optimization and Control · Mathematics 2021-07-27 Amit Verma , Mark Lewis , Gary Kochenberger

Charged particle reconstruction or track reconstruction is one of the most crucial components of pattern recognition in high-energy collider physics. It is known to entail enormous consumption of computing resources, especially when the…

Quantum Physics · Physics 2024-09-02 Hideki Okawa , Qing-Guo Zeng , Xian-Zhe Tao , Man-Hong Yung

The Steiner Tree Problem (STP) is a well-known NP-hard combinatorial optimization problem, which has wide applications in network design, integrated circuit layout, bioinformatics, and other fields. However, traditional algorithms often…

Quantum Physics · Physics 2026-03-05 Dan Li , Xiang-Hui Wu , Ji-Rong Liu

The Quadratic Unconstrained Binary Optimization (QUBO) problems are NP hard; thus, so far, there are no algorithms to solve them efficiently. There are exact methods like the Branch-and-Bound algorithm for smaller problems, and for larger…

Quantum Physics · Physics 2021-06-08 Máté Tibor Veszeli , Gábor Vattay

Variational Quantum Algorithms (VQAs) are promising methods for solving combinatorial optimization problems on noisy intermediate-scale quantum (NISQ) devices. However, benchmarking VQAs is difficult due to their stochastic behavior and the…

This paper explores the application of Quadratic Unconstrained Binary Optimization (QUBO) models in solving the Travelling Salesman Problem (TSP) through Quantum Annealing algorithms and Graph Neural Networks. Quantum Annealing (QA), a…

Quantum Physics · Physics 2024-10-01 Haoqi He

Quadratic unconstrained binary optimization (QUBO) tasks are very important in chemistry, finance, job scheduling, and so on, which can be represented using graph structures, with the variables as nodes and the interaction between them as…

Quantum Physics · Physics 2024-04-10 Yuhan Huang , Ferris Prima Nugraha , Siyuan Jin , Yichi Zhang , Bei Zeng , Qiming Shao

Machine learning and quantum computing are two technologies each with the potential for altering how computation is performed to address previously untenable problems. Kernel methods for machine learning are ubiquitous for pattern…

Graph partitioning is one of an important set of well-known compute-intense (NP-hard) graph problems that devolve to discrete constrained optimization. We sampled solutions to the problem via two different quantum-ready methods to…

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