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The success of deep learning methods relies on the availability of a large number of datasets with annotations; however, curating such datasets is burdensome, especially for medical images. To relieve such a burden for a landmark detection…

Computer Vision and Pattern Recognition · Computer Science 2021-03-09 Qingsong Yao , Quan Quan , Li Xiao , S. Kevin Zhou

Importance: Non-contrast head CT scan is the current standard for initial imaging of patients with head trauma or stroke symptoms. Objective: To develop and validate a set of deep learning algorithms for automated detection of following key…

Computer Vision and Pattern Recognition · Computer Science 2018-04-13 Sasank Chilamkurthy , Rohit Ghosh , Swetha Tanamala , Mustafa Biviji , Norbert G. Campeau , Vasantha Kumar Venugopal , Vidur Mahajan , Pooja Rao , Prashant Warier

Despite the large amount of brain CT data generated in clinical practice, the availability of CT datasets for deep learning (DL) research is currently limited. Furthermore, the data can be insufficiently or improperly prepared for machine…

Image and Video Processing · Electrical Eng. & Systems 2023-09-27 Alessandro Fontanella , Wenwen Li , Grant Mair , Antreas Antoniou , Eleanor Platt , Chloe Martin , Paul Armitage , Emanuele Trucco , Joanna Wardlaw , Amos Storkey

Accurate segmentation of coronary arteries is a pivotal process in assessing cardiovascular diseases. However, the intricate structure of the cardiovascular system presents significant challenges for automatic segmentation, especially when…

Image and Video Processing · Electrical Eng. & Systems 2023-11-20 Jonghoe Ku , Yong-Hee Lee , Junsup Shin , In Kyu Lee , Hyun-Woo Kim

The absence of pre-hospital physiological data in standard clinical datasets fundamentally constrains the early prediction of stroke, as patients typically present only after stroke has occurred, leaving the predictive value of continuous…

Machine Learning · Computer Science 2026-02-11 Jiaming Liu , Cheng Ding , Daoqiang Zhang

Segmenting stroke lesions in MRI is challenging due to diverse acquisition protocols that limit model generalisability. In this work, we introduce two physics-constrained approaches to generate synthetic quantitative MRI (qMRI) images that…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Liam Chalcroft , Jenny Crinion , Cathy J. Price , John Ashburner

Current deep learning-based approaches to lesion segmentation in neuroimaging often depend on high-resolution images and extensive annotated data, limiting clinical applicability. This paper introduces a novel synthetic data framework…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Liam Chalcroft , Ioannis Pappas , Cathy J. Price , John Ashburner

Infarcted brain tissue resulting from acute stroke readily shows up as hyperintense regions within diffusion-weighted magnetic resonance imaging (DWI). It has also been proposed that computed tomography perfusion (CTP) could alternatively…

Image and Video Processing · Electrical Eng. & Systems 2019-05-01 Jonathan Rubin , S. Mazdak Abulnaga

Coronary CT angiography (CCTA) has established its role as a non-invasive modality for the diagnosis of coronary artery disease (CAD). The CAD-Reporting and Data System (CAD-RADS) has been developed to standardize communication and aid in…

Stroke is among the top three causes of death worldwide, and accurate identification of stroke lesion boundaries is critical for diagnosis and treatment. Supervised deep learning methods have emerged as the leading solution for stroke…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Tianyi Ren , Juampablo E. Heras Rivera , Hitender Oswal , Yutong Pan , William Henry , Sophie Walters , Mehmet Kurt

Objective: Ultrasound (US) examination has unique advantages in diagnosing carpal tunnel syndrome (CTS) while identifying the median nerve (MN) and diagnosing CTS depends heavily on the expertise of examiners. To alleviate this problem, we…

Image and Video Processing · Electrical Eng. & Systems 2024-02-09 Jiayu Peng , Jiajun Zeng , Manlin Lai , Ruobing Huang , Dong Ni , Zhenzhou Li

Wearable electrocardiograph (ECG) recording and processing systems have been developed to detect cardiac arrhythmia to help prevent heart attacks. Conventional wearable systems, however, suffer from high energy consumption at both circuit…

Signal Processing · Electrical Eng. & Systems 2022-05-27 Jinbo Chen , Fengshi Tian , Jie Yang , Mohamad Sawan

Health sensing for chronic disease management creates immense benefits for social welfare. Existing health sensing studies primarily focus on the prediction of physical chronic diseases. Depression, a widespread complication of chronic…

Artificial Intelligence · Computer Science 2025-04-17 Jiaheng Xie , Xiaohang Zhao , Xiang Liu , Xiao Fang

The development of deep segmentation models for computational pathology (CPath) can help foster the investigation of interpretable morphological biomarkers. Yet, there is a major bottleneck in the success of such approaches because…

Background: Intracranial bleeding (IB) is a life-threatening condition caused by traumatic brain injuries, including epidural, subdural, subarachnoid, and intraparenchymal hemorrhages. Rapid and accurate detection is crucial to prevent…

Many clinical deep learning algorithms are population-based and difficult to interpret. Such properties limit their clinical utility as population-based findings may not generalize to individual patients and physicians are reluctant to…

Signal Processing · Electrical Eng. & Systems 2020-12-01 Dani Kiyasseh , Tingting Zhu , David A. Clifton

Cardiac segmentation of atriums, ventricles, and myocardium in computed tomography (CT) images is an important first-line task for presymptomatic cardiovascular disease diagnosis. In several recent studies, deep learning models have shown…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Sanguk Park , Minyoung Chung

Coronary artery calcification (CAC) is a strong predictor of cardiovascular risk but remains underutilized in clinical routine thoracic imaging due to the need for dedicated imaging protocols and manual annotation. We present DeepCAC2, a…

Image and Video Processing · Electrical Eng. & Systems 2026-03-27 Leonard Nürnberg , Simon Bernatz , Borek Foldyna , Michael T. Lu , Andrey Fedorov , Hugo JWL Aerts

Coronary microvascular dysfunction (CMD), characterized by impaired regulation of blood flow in the coronary microcirculation, plays a key role in the pathogenesis of ischemic heart disease and is increasingly recognized as a contributor to…

Computational Engineering, Finance, and Science · Computer Science 2025-12-25 Haizhou Yang , Jiyang Zhang , Brahmajee K. Nallamothu , Krishna Garikipati , C. Alberto Figueroa

Electrocardiogram (ECG) plays a foundational role in modern cardiovascular care, enabling non-invasive diagnosis of arrhythmias, myocardial ischemia, and conduction disorders. While machine learning has achieved expert-level performance in…

Signal Processing · Electrical Eng. & Systems 2025-07-22 Deyun Zhang , Xiang Lan , Shijia Geng , Qinghao Zhao , Sumei Fan , Mengling Feng , Shenda Hong